Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into Practice

2011 ◽  
pp. 297-304
Author(s):  
Jia-Perng Jennifer Wei ◽  
Wayne W. Grody
Keyword(s):  
Molecular Pathology ◽  
Laboratory Medicine ◽  
Evidence Based

Laboratory Medicine: Reference Values and Evidence-Based Medicine

Neonatology ◽  
2018 ◽  
pp. 2429-2432
Author(s):  
Mariangela Longini ◽  
Fabrizio Proietti ◽  
Francesco Bazzini ◽  
Elisa Belvisi
Keyword(s):  
Reference Values ◽  
Evidence Based Medicine ◽  
Laboratory Medicine ◽  
Evidence Based ◽  
Based Medicine

New laboratory markers for the management of rheumatoid arthritis patients

2014 ◽  
Vol 0 (0) ◽  
Author(s):  
Daniela P. Foti ◽  
Marta Greco ◽  
Eleonora Palella ◽  
Elio Gulletta
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Diagnosis ◽  
Health Problem ◽  
Laboratory Medicine ◽  
Social Health ◽  
Evidence Based ◽  
Pathogenetic Mechanism ◽  
Autoimmune Rheumatic Diseases ◽  
Laboratory Markers ◽  
Laboratory Biomarkers

AbstractRheumatoid arthritis, the most prominent of systemic autoimmune rheumatic diseases, represents an important social health problem. Recent insights into the immunopathogenic mechanism of this complex and multiform illness might open new perspectives for a more appropriate laboratory approach. In this review we focus on the most relevant pathogenetic mechanism; indicating the laboratory biomarkers specifically linked to early diagnosis, prognosis, evolutive aspects of the disease, and therapeutic efficacy. Evidence based on laboratory medicine could provide the best outcome for patients.

scholarly journals Evidence-Based Laboratory Medicine: How Well Do Laboratories Follow Recommendations and Guidelines? The Cardiac Marker Guideline Uptake in Europe (CARMAGUE) Study

2012 ◽  
Vol 58 (1) ◽  
pp. 305-306 ◽  
Author(s):  
Paul O Collinson ◽  
Marja P van Dieijen-Visser ◽  
Kari Pulkki ◽  
Angelika Hammerer-Lercher ◽  
Janne Suvisaari ◽  
...  
Keyword(s):  
Laboratory Medicine ◽  
Evidence Based ◽  
Cardiac Marker

scholarly journals The role of evidence-based laboratory medicine in health service

2002 ◽  
Vol 21 (3) ◽  
pp. 245-254 ◽  
Author(s):  
Nada Majkic-Singh
Keyword(s):  
Health Care ◽  
Clinical Experience ◽  
Evidence Based Medicine ◽  
Laboratory Tests ◽  
Laboratory Medicine ◽  
Systematic Research ◽  
Evidence Based ◽  
External Evidence ◽  
Based Medicine ◽  
The Impact

Evidence-based laboratory medicine (EBLM) is the use of the current best evidence of the utility of laboratory tests in making decisions about the care of individual patients. This practice means integrating laboratory and clinical experience with the last available external evidence from systematic research. It means that the definition of EBLM focuses on two key elements: experience and evidence from systematic research. Although the term evidence-based medicine (EBM) was created in Canada at Mc Master University by a group lad by Dr Gard Guyatt, there are various claims as to the origin of its practice. Regardless of its origins, many factors have come together over the past 30 years to drive the movement to EBM. One factor is those individual physicians, faced with numerous medical informations; the second factor is the global phenomenon of increasing health care costs and third is that patients who have generally more education, want the best in diagnostics and therapies. It means that evidence-based medicine has been driven by the need to cape with information overload, by costcontrol, and by public impatient for the best in diagnostics and treatment. Clinical guidelines care maps, and outcome measures are quality improvement tools for the appropriateness, efficiency and effectiveness of health services. Laboratory professionals must direct more effort to demonstrating the impact of laboratory tests on a greater variety of clinical outcomes. Evidence-based laboratory medicine aims to advise clinical diagnosis and management of disease through systematic researching and disseminating generalisible new knowledge that meets the standard of critical review on clinically effective practice of laboratory investigations. In laboratory medicine, the use of tests increases; new tests are constantly introduced, but "old" tests are seldom removed from the repertoire. This, together with limited public funds for the health care should underline the challenge for laboratory professionals to provide evidence for the utility of different tests. This practice means integrating laboratory and clinical experience with the best available external evidence from systematic research therefore, it is important that advice given by laboratory medicine professionals are sound and based on evidence in the pre-analytical, analytical, and post-analytical phases of the diagnostic process. This paper provides an insight into the rationale, methodology and the phases of the EBLM.

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