Pulmonary Surgery for Malignant Disease in the Elderly

Author(s):  
Sarah E. Billmeier ◽  
Michael T. Jaklitsch
Author(s):  
Sam Fox ◽  
Carlos Bravo-Iñiguez ◽  
Luis De Leon ◽  
Jeff Tarascio ◽  
Michael Jaklitsch

2010 ◽  
Vol 25 (6) ◽  
pp. 747-750 ◽  
Author(s):  
Fergal Donnellan ◽  
Garret Cullen ◽  
Daniel Cagney ◽  
Phil O’Halloran ◽  
Gavin C. Harewood ◽  
...  

2016 ◽  
Vol 27 (2) ◽  
pp. 81-85
Author(s):  
Homayra Tahseen Hossain ◽  
Quazi Tarikul Islam ◽  
Munshi MB Md Shoaib Adnan ◽  
Muntasir Ibne Mobin ◽  
HAM Nazmul Ahasan ◽  
...  

Tuberculosis is very common in our country. It can involve many organs and have broad spectrum of image presentation. It may resemble malignant diseases, especially in the elderly and thus confuse the judgement of the clinician. We report a case of a 58 year old gentleman presenting with chronic cough, low grade fever, weight loss for 16 months; features of progressive marrow failure for 8 months and severe low back pain without any neurological features for 2 months. The CT scan of spine revealed lytic lesions of vertebrae sparing the intervertebral discs, thus resembling metastatic lesions of bone. We approached this case as malignant disease initially, but found it to be a disseminated tuberculosis infection involving lungs, bone marrow and spine after a series of investigations. Though disseminated TB is not uncommon in our country, the purpose of presenting this case is to give emphasis that, clinicians should consider Pott’s disease (spinal tuberculosis) in the differential diagnosis of patients with back pain and destructive vertebral lesions. Proper diagnosis and anti-tuberculous treatment with or without surgery will result in cure of the patientBangladesh J Medicine Jul 2016; 27(2) : 81-85


2020 ◽  
Vol 21 (21) ◽  
pp. 7937
Author(s):  
Jan Brábek ◽  
Milan Jakubek ◽  
Fréderic Vellieux ◽  
Jiří Novotný ◽  
Michal Kolář ◽  
...  

Interleukin-6 (IL-6) is a cytokine with multifaceted effects playing a remarkable role in the initiation of the immune response. The increased level of this cytokine in the elderly seems to be associated with the chronic inflammatory setting of the microenvironment in aged individuals. IL-6 also represents one of the main signals in communication between cancer cells and their non-malignant neighbours within the tumour niche. IL-6 also participates in the development of a premetastatic niche and in the adjustment of the metabolism in terminal-stage patients suffering from a malignant disease. IL-6 is a fundamental factor of the cytokine storm in patients with severe COVID-19, where it is responsible for the fatal outcome of the disease. A better understanding of the role of IL-6 under physiological as well as pathological conditions and the preparation of new strategies for the therapeutic control of the IL-6 axis may help to manage the problems associated with the elderly, cancer, and serious viral infections.


Author(s):  
Sam Fox ◽  
Carlos Bravo-Iñiguez ◽  
Luis De Leon ◽  
Jeff Tarascio ◽  
Michael Jaklitsch

2009 ◽  
Vol 18 (1) ◽  
Author(s):  
Geirmund Myklebust ◽  
Jan Tore Gran

<p>Polymyalgia rheumatica (PMR) er en sykdom som rammer personer over 50 år og som forekommer hyppigst i de Skandinaviske land. Insidensen i Norge er beregnet til omkring 112 per 100.000 personer over 50 år. Mortaliteten er ikke signifikant økt, og det er ingen sikker økt risiko for utvikling av kreftsykdom. Ikke sjelden blir diagnostikk og behandling ivaretatt av allmennpraktiserende leger slik at kunnskap fremkommet ved analyser av sykehusinnlagte pasienter ikke umiddelbart vil gjelde hele pasientpopulasjonen. Vår kunnskap om sykdommen er fortsatt fragmentert og mangelfull. I Norge burde det være gode forutsetninger for å kunne gjennomføre god epidemiologisk og klinisk forskning basert på et samarbeid mellom første- og annenlinjetjenesten.</p><p>Polymyalgia rheumatica (PMR) is a common disease in the elderly. The highest incidence is found in Scandinavia. There is no increased risk of concomitant malignant disease, and mortality equals that of the general population aged 50 years or more. In most cases, diagnosis and therapy are made by general practitioners. The knowlegde about this condition is still incomplete. In Norway, scientific research should be organised through collaboration between referral centers and general practitioners</p>


Sign in / Sign up

Export Citation Format

Share Document