n-3 Polyunsaturated Fatty Acids in the Treatment of Pancreatic Cancer Cachexia

1999 ◽  
pp. 311-324
Author(s):  
M. D. Barber ◽  
J. A. Ross ◽  
K. C. H. Fearon
Keyword(s):  
Pancreatic Cancer ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Cancer Cachexia

S2021 Pronounced Effects of N-3 and N-6 Polyunsaturated Fatty Acids in Pancreatic Cancer Cells Using Three-Dimensional Growth Assays

2009 ◽  
Vol 136 (5) ◽  
pp. A-315
Author(s):  
Aihua Li ◽  
Jenny L. Park ◽  
Sharon Kang ◽  
Howard A. Reber ◽  
Oscar J. Hines ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Cancer Cells ◽  
Three Dimensional ◽  
Pancreatic Cancer Cells ◽  
Dimensional Growth

The Complexity of Omega-3 Fatty Acid Modulation of Signaling Pathways Related to Pancreatic Cancer

2018 ◽  
Vol 25 (22) ◽  
pp. 2608-2623 ◽  
Author(s):  
Carolina Torres ◽  
Andrew M. Diaz ◽  
Daniel R. Principe ◽  
Paul J. Grippo
Keyword(s):  
Pancreatic Cancer ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Signaling Pathways ◽  
Intracellular Signaling ◽  
Biological Activities ◽  
The United States ◽  
Major Public Health Problem ◽  
Wide Range ◽  
Membrane Structure And Function

Cancer is a major public health problem worldwide and is the second leading cause of death in the United States. Although cancer death rate has dropped by 23% since 1991, there are certain types of cancer for which death rates are still increasing, such as pancreatic cancer. There is an urgent need to find new therapies that could help improve this dreadful outcome. In this regard, the role of nutrition in health and disease has attracted much attention. Several dietary components are involved in metabolic, physiologic and cell signaling affecting tumor growth and progression. Although lipids, and more specifically polyunsaturated fatty acids, have been traditionally studied due to their health effects in cardiovascular disease, it is now clear that they can impact an extensive array of cellular processes that influence a wide range of diseases such as type II diabetes, inflammatory disorders and cancer. These biological activities may be grouped as regulation of: (1) membrane structure and function, (2) intracellular signaling pathways, (3) transcription factor activity, (4) gene expression, and (5) production of bioactive lipid mediators. The aim of this review is to assimilate the current state of knowledge about these potential mechanism(s) of action and signaling pathways modulated by polyunsaturated fatty acids in pancreatic cancer.

Cancer Cachexia and Tumor Growth Reduction in Walker 256 Tumor-Bearing Rats Supplemented With N-3 Polyunsaturated Fatty Acids for One Generation

2003 ◽  
Vol 46 (1) ◽  
pp. 52-58 ◽  
Author(s):  
Valeria Togni ◽  
Claudia C. C. Ota ◽  
Alessandra Folador ◽  
O. Tchaikovski Junior ◽  
Julia Aikawa ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Tumor Growth ◽  
Cancer Cachexia ◽  
Growth Reduction ◽  
Tumor Bearing ◽  
Walker 256 ◽  
Walker 256 Tumor
Sign in / Sign up

Export Citation Format

Share Document