Case Studies: Processes & Problems on the Early Stage of Localization

Author(s):  
Guo Yi
Keyword(s):  
Author(s):  
Penny Farfan

This introduction sets forth the book’s central argument and establishes the historical, theoretical, and critical context for its case studies. In the late nineteenth and early twentieth centuries, modern sexual identities emerged into view while at the same time being rendered invisible, as in Oscar Wilde’s 1895 trial on charges of gross indecency and the 1928 obscenity trial of Radclyffe Hall’s The Well of Loneliness. Early stage representations of homosexuality were typically coded or censored, yet the majority of the works considered in this book were highly visible in their subversions of conventional gender and sexual norms. Queer readings of these plays and performances establish connections across high and popular cultural domains, demonstrating that some of traditional modernism’s perceived failures, rejects, and outliers were modernist through their sexual dissidence. These insights in turn contribute to a more precise understanding of how modernity was mediated and how such mediations enacted change.


2021 ◽  
Author(s):  
Alex Mariakakis ◽  
Ravi Karkar ◽  
Shwetak N Patel ◽  
Julie A Kientz ◽  
James Fogarty ◽  
...  

BACKGROUND Developers, designers, and researchers use rapid prototyping methods to project the adoption and acceptability of their health intervention technology (HIT) before the technology becomes mature enough to be deployed. Although these methods are useful for gathering feedback that advances the development of HITs, they rarely provide usable evidence that can contribute to our broader understanding of HITs. OBJECTIVE In this research, we aim to develop and demonstrate a variation of vignette testing that supports developers and designers in evaluating early-stage HIT designs while generating usable evidence for the broader research community. METHODS We proposed a method called <i>health concept surveying</i> for untangling the causal relationships that people develop around conceptual HITs. In health concept surveying, investigators gather reactions to design concepts through a scenario-based survey instrument. As the investigator manipulates characteristics related to their HIT, the survey instrument also measures proximal cognitive factors according to a health behavior change model to project how HIT design decisions may affect the adoption and acceptability of an HIT. Responses to the survey instrument were analyzed using path analysis to untangle the causal effects of these factors on the outcome variables. RESULTS We demonstrated health concept surveying in 3 case studies of sensor-based health-screening apps. Our first study (N=54) showed that a wait time incentive could influence more people to go see a dermatologist after a positive test for skin cancer. Our second study (N=54), evaluating a similar application design, showed that although visual explanations of algorithmic decisions could increase participant trust in negative test results, the trust would not have been enough to affect people’s decision-making. Our third study (N=263) showed that people might prioritize test specificity or sensitivity depending on the nature of the medical condition. CONCLUSIONS Beyond the findings from our 3 case studies, our research uses the framing of the Health Belief Model to elicit and understand the intrinsic and extrinsic factors that may affect the adoption and acceptability of an HIT without having to build a working prototype. We have made our survey instrument publicly available so that others can leverage it for their own investigations.


2019 ◽  
pp. 296-317
Author(s):  
Kostas Kardamis

The Ionian Islands were at an early stage cut off from the Eastern Roman Empire, experienced the changes that came with the Renaissance, actively participated in the Enlightenment and were in contact with the multifarious ideologies of the 19th century. These factors transformed their art music, which followed the ‘western’ trends. In this context, ‘orientalism’ appeared as an additional creative element in certain indigenous composers’ works. Its use ranged from the stereotypical ‘western’ approach regarding the Orient to the employment of ‘oriental’ elements as media of political (especially during the struggles for the Islands’ annexation to the Greek Kingdom), national (as a conventional ‘Greek characteristic’) and social statements, and as a way for the works’ entrepreneurial promotion to a larger audience. The chapter discusses these changing—and often concurrent and diverging—attitudes through case studies; it stresses that ‘orientalism’ never became a compositional fixation for Ionian Islands composers.


2019 ◽  
Vol 39 (7) ◽  
pp. 857-866 ◽  
Author(s):  
Lucy Abel ◽  
Bethany Shinkins ◽  
Alison Smith ◽  
Andrew J. Sutton ◽  
Gurdeep S. Sagoo ◽  
...  

Diagnostic tests are expensive and time-consuming to develop. Early economic evaluation using decision modeling can reduce commercial risk by providing early evidence on cost-effectiveness. The National Institute for Health Research Diagnostic Evidence Co-operatives (DECs) was established to catalyze evidence generation for diagnostic tests by collaborating with commercial developers; DEC researchers have consequently made extensive use of early modeling. The aim of this article is to summarize the experiences of the DECs using early modeling for diagnostics. We draw on 8 case studies to illustrate the methods, highlight methodological strengths and weaknesses particular to diagnostics, and provide advice. The case studies covered diagnosis, screening, and treatment stratification. Treatment effectiveness was a crucial determinant of cost-effectiveness in all cases, but robust evidence to inform this parameter was sparse. This risked limiting the usability of the results, although characterization of this uncertainty in turn highlighted the value of further evidence generation. Researchers evaluating early models must be aware of the importance of treatment effect evidence when reviewing the cost-effectiveness of diagnostics. Researchers planning to develop an early model of a test should also 1) consult widely with clinicians to ensure the model reflects real-world patient care; 2) develop comprehensive models that can be updated as the technology develops, rather than taking a “quick and dirty” approach that may risk producing misleading results; and 3) use flexible methods of reviewing evidence and evaluating model results, to fit the needs of multiple decision makers. Decision models can provide vital information for developers at an early stage, although limited evidence mean researchers should proceed with caution.


10.2196/30474 ◽  
2022 ◽  
Vol 9 (1) ◽  
pp. e30474
Author(s):  
Alex Mariakakis ◽  
Ravi Karkar ◽  
Shwetak N Patel ◽  
Julie A Kientz ◽  
James Fogarty ◽  
...  

Background Developers, designers, and researchers use rapid prototyping methods to project the adoption and acceptability of their health intervention technology (HIT) before the technology becomes mature enough to be deployed. Although these methods are useful for gathering feedback that advances the development of HITs, they rarely provide usable evidence that can contribute to our broader understanding of HITs. Objective In this research, we aim to develop and demonstrate a variation of vignette testing that supports developers and designers in evaluating early-stage HIT designs while generating usable evidence for the broader research community. Methods We proposed a method called health concept surveying for untangling the causal relationships that people develop around conceptual HITs. In health concept surveying, investigators gather reactions to design concepts through a scenario-based survey instrument. As the investigator manipulates characteristics related to their HIT, the survey instrument also measures proximal cognitive factors according to a health behavior change model to project how HIT design decisions may affect the adoption and acceptability of an HIT. Responses to the survey instrument were analyzed using path analysis to untangle the causal effects of these factors on the outcome variables. Results We demonstrated health concept surveying in 3 case studies of sensor-based health-screening apps. Our first study (N=54) showed that a wait time incentive could influence more people to go see a dermatologist after a positive test for skin cancer. Our second study (N=54), evaluating a similar application design, showed that although visual explanations of algorithmic decisions could increase participant trust in negative test results, the trust would not have been enough to affect people’s decision-making. Our third study (N=263) showed that people might prioritize test specificity or sensitivity depending on the nature of the medical condition. Conclusions Beyond the findings from our 3 case studies, our research uses the framing of the Health Belief Model to elicit and understand the intrinsic and extrinsic factors that may affect the adoption and acceptability of an HIT without having to build a working prototype. We have made our survey instrument publicly available so that others can leverage it for their own investigations.


2021 ◽  
Vol 26 (2) ◽  
Author(s):  
Yuanxin Rong

This paper addresses the topic of building platform-based companies in biopharma.  We provide a short literature review on the topic, followed by a discussion of financing growth of platform companies.  This is followed by case studies on four pioneering biopharma companies that cover the era of the mid-1990s until today.  These companies are all well recognized pioneers and have gone thru their life cycles from founding, to building portfolios of products, to acquisition. Our mini-case studies include Millennium Pharmaceuticals (now a unit of Takeda), Alnylam, Moderna, and Kymera.) These also cover different technology bases for their respective platforms that have emerged during the last two decades since the emergence of the genomics revolution.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Richard Hanage ◽  
Pekka Stenholm ◽  
Jonathan M. Scott ◽  
Mark A.P. Davies

PurposeThe purpose of this paper is to respond to the call by McMullen and Dimov (2013) for a clearer understanding of entrepreneurial journeys by investigating the entrepreneurial capitals and micro-processes of seven young early stage entrepreneurs who all exited their businesses within 3 years of start-up.Design/methodology/approachThe authors analysed empirical data from concurrent in-depth interviews which generated rich longitudinal case studies. Theory-building then led to a proposed “Longitudinal Dynamic Process Framework” of entrepreneurial goals, processes and capitals.FindingsThe framework builds on prior studies by integrating entrepreneurial processes and decisions into two feedback loops based on continuous review and learning. It thereby enhances understanding of the dynamics of new business development and unfolds the early stage ventures entrepreneurs' business exits.Research limitations/implicationsThe findings are based on a small purposive sample. However, the main implication for research and theory is showing how the entrepreneurial capitals are dynamic and influenced by entrepreneurs' environment, and also separating entrepreneurs' personal issues from their business issues.Practical implicationsThe findings challenge some assumptions of policymakers and offer new insights for practitioners and early stage entrepreneurs. These include having more realistic case-studies of the entrepreneurial journey, recognizing the need to be agile and tenacious to cope with challenges, understanding how capitals can interact in complementary ways and that entrepreneurial processes can be used to leverage them at appropriate stages of the start-ups.Originality/valueThe concurrent longitudinal analysis and theory-building complements extant cross-sectional studies by identifying and analysing the detailed processes of actual business start-ups and exits. The proposed framework thereby adds coherence to earlier studies and helps to explain early stage entrepreneurial development, transformation of capitals and business exit.


2019 ◽  
Vol 25 (3) ◽  
pp. 456-475 ◽  
Author(s):  
Marlon Meier ◽  
Kim Hua Tan ◽  
Ming K. Lim ◽  
Leanne Chung

Purpose Fast-changing customer demands and rising requirements in product performance constantly challenge sports equipment manufacturers to come up with new and improved products to stay competitive. Additive manufacturing (AM), also referred to as 3D printing, can enhance the development of new products by providing an efficient approach of rapid prototyping. The purpose of this paper is to analyse the current adoption of AM technologies in the innovation process of the sports industry, i.e. level of awareness; how it is implemented; and it impact on the innovation process. Design/methodology/approach This work followed a qualitative research approach. After conducting a research of the current literature, this paper presents findings that include case studies from different companies, as well as a semi-structured interview with an outdoor sports equipment manufacturer. Companies from all over the world and of different sizes from under 100 employees to over 70,000 employees were considered in this research. Findings Literature research shows that AM brings many possibilities to enhance the innovation process, and case studies indicated several obstacles that hinder the technology from fully unfolding. AM is still at the early stage of entering the sports equipment industry and its potential benefits have not been fully exploited yet. The findings generated from the research of real-life practices show that AM provides several benefits when it comes to the innovation process, such as a faster development process, an optimised output, as well as the possibility to create new designs. However, companies are not yet able to enhance the innovation process in a way that leads to new products and new markets with AM. Limitations, including a small range of process able material and an inefficient mass production, still restrain the technology and lead to unused capability. Nevertheless, future prospects indicate the growing importance of AM in the innovation process and show that its advancement paves the way to new and innovative products. Research limitations/implications Limitations exist in the qualitative approach of this study, which does not include the quantitative verification of the results. Originality/value Very few studies have been conducted to investigate how firms can harvest AM to increase their innovation capabilities. How firms can use AM to shorten product development time is an emerging topic in business and operations but has not been studied widely. This paper aims to address this gap.


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