Regulation of Secretion in Human Basophils

1999 ◽  
pp. 372-389
Author(s):  
Donald MacGlashan
Keyword(s):  
Regulation Of Secretion ◽  
Human Basophils

Perspectives on the Regulation of Secretion from Human Basophils and Mast Cells

2000 ◽  
pp. 195-207 ◽  
Author(s):  
Macglashan JR Donald ◽  
Sandra Lavens-Phillips ◽  
Katsushi Miura
Keyword(s):  
Mast Cells ◽  
Regulation Of Secretion ◽  
Human Basophils

Ultrastructural Aspects of Golgi Complex Function in Parathyroid Cells of Winter Frogs

1973 ◽  
Vol 31 ◽  
pp. 680-681
Author(s):  
William J. Dougherty
Keyword(s):  
Golgi Complex ◽  
Secretory Granules ◽  
Complex Function ◽  
Secretory Activity ◽  
Secretory Proteins ◽  
Perivascular Spaces ◽  
Pituitary Cells ◽  
Electron Microscopic ◽  
Ca Ions ◽  
Regulation Of Secretion

The regulation of secretion in exocrine and endocrine cells has long been of interest. Electron microscopic and other studies have demonstrated that secretory proteins synthesized on ribosomes are transported by the rough ER to the Golgi complex where they are concentrated into secretory granules. During active secretion, secretory granules fuse with the cell membrane, liberating and discharging their contents into the perivascular spaces. When secretory activity is suppressed in anterior pituitary cells, undischarged secretory granules may be degraded by lysosomes. In the parathyroid gland, evidence indicates that the level of blood Ca ions regulates both the production and release of parathormone. Thus, when serum Ca is low, synthesis and release of parathormone are both stimulated; when serum Ca is elevated, these processes are inhibited.

scholarly journals Bimodal regulation of secretion by cytoplasmic Ca2+as demonstrated by the parathyroid

FEBS Letters ◽  
1987 ◽  
Vol 213 (1) ◽  
pp. 195-198 ◽  
Author(s):  
Peter Nygren ◽  
Rolf Larsson ◽  
Erik Lindh ◽  
Sverker Ljunghal ◽  
Jonas Rastad ◽  
...  
Keyword(s):  
Regulation Of Secretion

A novel tool for the detection of allergic sensitization combining protein microarrays with human basophils

2007 ◽  
Vol 37 (12) ◽  
pp. 1854-1862 ◽  
Author(s):  
J. Lin ◽  
N. Renault ◽  
H. Haas ◽  
G. Schramm ◽  
S. Vieths ◽  
...  
Keyword(s):  
Allergic Sensitization ◽  
Protein Microarrays ◽  
Human Basophils
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