The Role of Growth Hormone Releasing Hormone (GHRH) and Growth Hormone (GH) in the Onset of Puberty and During Glucocorticoid-Altered Growth

1996 ◽  
pp. 185-209 ◽  
Author(s):  
Lisa K. Conley ◽  
Michel L. Aubert ◽  
Andrea Giustina ◽  
William B. Wehrenberg
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone

Role of Aging on Growth Hormone and Prolactin Release after Growth Hormone-Releasing Hormone and Domperidone in Man

1987 ◽  
Vol 27 (3) ◽  
pp. 134-140 ◽  
Author(s):  
M. Giusti ◽  
A. Lomeo ◽  
G. Marini ◽  
R. Attanasio ◽  
A. Barreca ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Releasing Hormone ◽  
Prolactin Release ◽  
Releasing Hormone

The role of cholinergic tone in modulating the growth hormone response to growth hormone-releasing hormone in normal man

Metabolism ◽  
1991 ◽  
Vol 40 (5) ◽  
pp. 519-523 ◽  
Author(s):  
Andrea Giustina ◽  
Simonetta Bossoni ◽  
Corrado Bodini ◽  
Mauro Doga ◽  
Angela Girelli ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Response ◽  
Growth Hormone Releasing Hormone ◽  
Hormone Response ◽  
Releasing Hormone ◽  
Cholinergic Tone ◽  
Normal Man

Role of growth hormone-releasing hormone on pentagastrin-induced growth hormone release in normal subjects

1991 ◽  
Vol 14 (3) ◽  
pp. 241-244 ◽  
Author(s):  
J. F. Garcia-Rojas ◽  
A. Mangas ◽  
A. Barba ◽  
J. Millan ◽  
C. Dieguez ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Normal Subjects ◽  
Hormone Release ◽  
Growth Hormone Release ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone

scholarly journals The role of pit-1 in the regulation of the rat growth hormone-releasing hormone receptor gene transcription by glucocorticoids

2005 ◽  
Vol 35 (3) ◽  
pp. 477-488 ◽  
Author(s):  
Haruo Nogami ◽  
Yoshiki Hiraoka ◽  
Kiyomoto Ogasawara ◽  
Sadakazu Aiso ◽  
Setsuji Hisano
Keyword(s):  
Growth Hormone ◽  
Gene Transcription ◽  
Receptor Gene ◽  
Inhibitory Effect ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Proper Distance ◽  
Ghrh Receptor ◽  
Rat Growth

Glucocorticoids are involved in the regulation of the rat growth hormone-releasing hormone (GHRH) receptor gene expression, but they act only in the presence of the pituitary specific transcription factor, pit-1. In this study, the role of pit-1 in the glucocorticoid stimulation of the GHRH-receptor gene transcription was examined. The results suggest the presence of a silencer element in the promoter and it is postulated that pit-1 permits glucocorticoid action through suppressing the inhibitory effect of an as yet unknown factor that binds to this element. The present results also suggest that the synergistic activation of the rat GHRH-receptor gene transcription depends on the proper distance between the proximal glucocorticoid response element and the pit-1 binding site.

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