Cytoreductive approach to treatment of multiple liver metastases

1994 ◽  
pp. 13-20
Author(s):  
Paul H. Sugarbaker ◽  
Mark A. Steves
Keyword(s):  
Liver Metastases ◽  
Multiple Liver Metastases

scholarly journals Complete remission of multiple liver metastases with only partial response of the primary rectal cancer after neoadjuvant chemotherapy

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Satomi Miura ◽  
Kyoji Ito ◽  
Nobuyuki Takemura ◽  
Fuminori Mihara ◽  
Tomomichi Kiyomatsu ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Complete Remission ◽  
Partial Response ◽  
Liver Metastases ◽  
Primary Rectal Cancer ◽  
Multiple Liver Metastases

scholarly journals Efficacy of Combined Regional Inductive Moderate Hyperthermia and Chemotherapy in Patients With Multiple Liver Metastases From Breast Cancer

2018 ◽  
Vol 17 ◽  
pp. 153303381880600 ◽  
Author(s):  
Mykhailo Yu Klimanov ◽  
Liubov A. Syvak ◽  
Valerii E. Orel ◽  
G. V. Lavryk ◽  
Tetiana Ye Tarasenko ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Liver Metastases ◽  
Multiple Liver Metastases

scholarly journals Is time to recosinder upfront surgery in case of multiple liver metastases? A weighted comparison in the era of parenchyma-sparing surgery

HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S802
Author(s):  
F. Milana ◽  
S. Famularo ◽  
M. Cimino ◽  
P. Corleone ◽  
B. Branciforte ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Parenchyma Sparing ◽  
Multiple Liver Metastases

scholarly journals STUDY OF THE POSSIBILITIES OF PREOPERATIVE CHEMOTHERAPY IN MULTIPLE METASTASIS OF COLORECTAL CANCER IN THE LIVER

2020 ◽  
Vol 1 (8(77)) ◽  
pp. 8-11
Author(s):  
Kh.D. Islamov ◽  
Sh.Kh. Niyozova
Keyword(s):  
Colorectal Cancer ◽  
Side Effects ◽  
Liver Metastases ◽  
Preoperative Chemotherapy ◽  
High Frequency ◽  
Partial Regression ◽  
Multiple Metastasis ◽  
Preoperative Ct ◽  
Multiple Liver Metastases ◽  
Surgical Operations

Preoperative chemotherapy (CT) in 35 patients with colorectal cancer (CRC) with liver metastases demonstrated a high frequency of objective effects - in 22 (62.9%) patients, stabilization was noted in 10 (28.6%) cases. With bilobar liver metastases and the use of oxaliplatin-containing regimens, partial regression was 62.9%. Side effects in most cases were clinically insignificant, no deaths were observed. The results obtained demonstrate the possibility of performing extended surgical operations in the majority of CRC patients with multiple liver metastases after preoperative CT.

scholarly journals A Case of AFP Producing Gastric Cancer with Multiple Liver Metastases Successfully Treated with Low Dose FAP Via Hepatic Artery

2002 ◽  
Vol 27 (6) ◽  
pp. 902-907
Author(s):  
Toshio TAKAYAMA ◽  
Masahiko SUGANO ◽  
Toshiki KAMANO ◽  
Masahiko TURUMARU ◽  
Yasuo HAYASHIDA ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Liver Metastases ◽  
Hepatic Artery ◽  
Low Dose ◽  
Multiple Liver Metastases

scholarly journals A Case of Multiple Liver Metastases after Surgery in Elderly HER2-Positive Breast Cancer in Which Anastrozole + Trastuzumab Was Ineffective but T-DM1 Was Effective

2021 ◽  
pp. 1632-1637
Author(s):  
Tomohiro Shidahara ◽  
Shozo Ohsumi ◽  
Yuichiro Miyoshi ◽  
Mina Takahashi ◽  
Seiki Takashima ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Liver Metastases ◽  
Growth Factor Receptor ◽  
Complete Response ◽  
Lymph Node Biopsy ◽  
Her2 Positive ◽  
Her2 Positive Breast Cancer ◽  
Pathological Result ◽  
Multiple Liver Metastases ◽  
Positive Breast Cancer

Chemotherapy is often difficult to treat human epidermal growth factor receptor 2 (HER2)-positive metastatic recurrent breast cancer in the elderly, and no standard treatment has been established at this point. We experienced a case in which trastuzumab (Tmab) + anastrozole (ANA) was ineffective (progressive disease; PD) in elderly HER2-positive breast cancer with postoperative multiple liver metastases, but T-DM1 was significantly effective (complete response; CR), and treatment could be continued safely. An 82-year-old woman was referred to our department with a right breast mass. A close examination revealed right breast cancer cT1bN0M0 cStage I, and total mastectomy and sentinel lymph node biopsy were performed. The postoperative pathological result was pT1bN0M0 pStage I (luminal HER2 type). The patient was elderly and had no adjuvant treatment after the operation. Approximately 2 years after the operation, multiple liver metastases were observed, and treatment with ANA and Tmab was started. Four months later, MRI showed that the number of multiple liver metastases increased. The patient was diagnosed with PD, and the anti-HER2 drug was changed from trastuzumab to trastuzumab emtansine (T-DM1). The dose was reduced due to vomiting (grade 3). Two months later, MRI showed that the multiple liver metastases shrank and became obscure after 5 months. After that, T-DM1 was continued, and the disease did not worsen. In elderly people with difficulty in administering chemotherapy, T-DM1 may have a safe and sufficient therapeutic effect by adjusting the dose and managing side effects appropriately.

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