Diversity of fatty acid-binding protein structure and function: studies with fluorescent ligands

1993 ◽  
pp. 45-53
Author(s):  
Judith Storch
Keyword(s):  
Fatty Acid ◽  
Protein Structure ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Structure And Function ◽  
Protein Structure And Function ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Fluorescent Ligands ◽  
And Function

Fatty acid binding protein isoforms: structure and function

1998 ◽  
Vol 92 (1) ◽  
pp. 1-25 ◽  
Author(s):  
Friedhelm Schroeder ◽  
Christopher A Jolly ◽  
Tae-Hyeon Cho ◽  
Andrey Frolov
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Structure And Function ◽  
Protein Isoforms ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
And Function

Molecular Cloning and Tissue-Specific Expression of the Heart-Type Fatty Acid-Binding Protein (H-FABP)

2011 ◽  
Vol 343-344 ◽  
pp. 438-447
Author(s):  
Cheng Li Zheng ◽  
Gang Yi Xu ◽  
Dai Hua Wang
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Structure And Function ◽  
Longissimus Muscle ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Leg Muscle ◽  
And Function ◽  
Fabp Gene

In order to understand the structure and function of H-FABP gene, reveal the effect on the heart-type fatty acid-binding protein in goat, the cDNA of H-FABP gene was cloned and sequenced from heart of Tianfu goat （an emerging breed） by T-A clone techniques. The structure and function of H-FABP were analyzed by bioinformatics, and the gene expression profile in different tissues was examined by real-time PCR. The results showed that the full sequence of H-FABP cDNA is 650 bp, containing 402 bp coding region (CDS) encoding 133 amino acids. The isoelectric point (pI) of the protein is 6.11, and the molecular weight is 14.7 kDa. There were eight phosphorylational sites in this protein. The secondary structure of the protein was mainly α-helix, random coil and extended strand structure. The deduced amino acid sequence of H-FABP shared significant identity with the H-FABP from other mammals. The phylogenic tree based on H-FABP protein sequence was detected the closest relationship to cattle. A predicted 3D model was constructed by homology modeling. H-FABP mRNA is a broad-spectrum expression gene, which was detected in heart, liver, spleen, lung, kidney, longissimus muscle and leg muscle. In particular, high expression levels of H-FABP mRNA were detected in heart, longissimus muscle and leg muscle, but low expressions were observed in liver tissue.

Expression and function of fatty acid–binding protein 4 during mouse decidualization

2011 ◽  
Vol 95 (8) ◽  
pp. 2749-2752.e5 ◽  
Author(s):  
Zhen Tian ◽  
Zhen-Ao Zhao ◽  
Xiao-Huan Liang ◽  
Xiu-Hong Zhang ◽  
Ai-Guo Sha ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
And Function
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