Potential Role of Mast Cell Proteases in Asthma

1992 ◽  
pp. 51-61
Author(s):  
Jay A. Nadel
Keyword(s):  
Mast Cell ◽  
Potential Role

scholarly journals 28 Potential Role of Scavenger Receptors in Human Mast Cell Cytokine Response to Oxidized ldl

2012 ◽  
Vol 5 ◽  
pp. S10
Author(s):  
Rita Faigerc ◽  
Jani Lappalainenc ◽  
Wolfgang J. Schneider ◽  
Petri Kovanen ◽  
Francesca Levi-Schaffer
Keyword(s):  
Mast Cell ◽  
Potential Role ◽  
Oxidized Ldl ◽  
Cytokine Response ◽  
Human Mast Cell ◽  
Scavenger Receptors

scholarly journals The emerging role of mast cells in liver disease

2017 ◽  
Vol 313 (2) ◽  
pp. G89-G101 ◽  
Author(s):  
Veronica Jarido ◽  
Lindsey Kennedy ◽  
Laura Hargrove ◽  
Jennifer Demieville ◽  
Joanne Thomson ◽  
...  
Keyword(s):  
Mast Cell ◽  
Liver Disease ◽  
Mast Cells ◽  
Autoimmune Disease ◽  
Liver Cancer ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Liver Diseases ◽  
Potential Role

The depth of our knowledge regarding mast cells has widened exponentially in the last 20 years. Once thought to be only important for allergy-mediated events, mast cells are now recognized to be important regulators of a number of pathological processes. The revelation that mast cells can influence organs, tissues, and cells has increased interest in mast cell research during liver disease. The purpose of this review is to refresh the reader’s knowledge of the development, type, and location of mast cells and to review recent work that demonstrates the role of hepatic mast cells during diseased states. This review focuses primarily on liver diseases and mast cells during autoimmune disease, hepatitis, fatty liver disease, liver cancer, and aging in the liver. Overall, these studies demonstrate the potential role of mast cells in disease progression.

scholarly journals Potential role of mast cell chymase in chronic proliferative inflammation of the skin

1998 ◽  
Vol 76 ◽  
pp. 161
Author(s):  
Eiichi Kakizoe ◽  
Yoriko Nishikori ◽  
Yuta Kobayashi ◽  
Satoshi Dekio ◽  
Hideki Okunishi
Keyword(s):  
Mast Cell ◽  
Potential Role ◽  
Mast Cell Chymase

POPDC proteins and cardiac function

2019 ◽  
Vol 47 (5) ◽  
pp. 1393-1404 ◽  
Author(s):  
Thomas Brand
Keyword(s):  
Potential Role ◽  
Striated Muscle ◽  
Short Review ◽  
Effector Proteins ◽  
Muscle Disease ◽  
Disease Genes ◽  
Protein Protein Interaction ◽  
Interaction Partners ◽  
And Function

Abstract The Popeye domain-containing gene family encodes a novel class of cAMP effector proteins in striated muscle tissue. In this short review, we first introduce the protein family and discuss their structure and function with an emphasis on their role in cyclic AMP signalling. Another focus of this review is the recently discovered role of POPDC genes as striated muscle disease genes, which have been associated with cardiac arrhythmia and muscular dystrophy. The pathological phenotypes observed in patients will be compared with phenotypes present in null and knockin mutations in zebrafish and mouse. A number of protein–protein interaction partners have been discovered and the potential role of POPDC proteins to control the subcellular localization and function of these interacting proteins will be discussed. Finally, we outline several areas, where research is urgently needed.

The Effect of Path Length and Display Size on Memory for Spatial Information

2012 ◽  
Vol 59 (3) ◽  
pp. 147-152 ◽  
Author(s):  
Katherine Guérard ◽  
Sébastien Tremblay
Keyword(s):  
Path Length ◽  
Potential Role ◽  
Spatial Information ◽  
Recall Performance ◽  
Minor Role ◽  
Length Effect ◽  
Serial Memory ◽  
Fixed Reference ◽  
A Minor

In serial memory for spatial information, some studies showed that recall performance suffers when the distance between successive locations increases relatively to the size of the display in which they are presented (the path length effect; e.g., Parmentier et al., 2005) but not when distance is increased by enlarging the size of the display (e.g., Smyth & Scholey, 1994). In the present study, we examined the effect of varying the absolute and relative distance between to-be-remembered items on memory for spatial information. We manipulated path length using small (15″) and large (64″) screens within the same design. In two experiments, we showed that distance was disruptive mainly when it is varied relatively to a fixed reference frame, though increasing the size of the display also had a small deleterious effect on recall. The insertion of a retention interval did not influence these effects, suggesting that rehearsal plays a minor role in mediating the effects of distance on serial spatial memory. We discuss the potential role of perceptual organization in light of the pattern of results.

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