Epidermal Dendritic Cells in Immunodeficient Mice

1991 ◽  
pp. 59-76
Author(s):  
Eli Sprecher ◽  
Leonard D. Shultz ◽  
Yechiel Becker
Keyword(s):  
Dendritic Cells ◽  
Immunodeficient Mice ◽  
Epidermal Dendritic Cells

scholarly journals Molecular Mechanisms Involved in the Migration of Epidermal Dendritic Cells in the Skin

1999 ◽  
Vol 4 (2) ◽  
pp. 169-172 ◽  
Author(s):  
Koichiro Nakamura ◽  
Kunihiko Tamaki ◽  
Atsushi Saitoh ◽  
Nami Yasaka ◽  
Masutaka Furue
Keyword(s):  
Dendritic Cells ◽  
Molecular Mechanisms ◽  
Epidermal Dendritic Cells

scholarly journals HIV-1 Selection by Epidermal Dendritic Cells during Transmission across Human Skin

1998 ◽  
Vol 187 (10) ◽  
pp. 1623-1631 ◽  
Author(s):  
Jeanette C. Reece ◽  
Amanda J. Handley ◽  
E. John Anstee ◽  
Wayne A. Morrison ◽  
Suzanne M. Crowe ◽  
...  
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Human Skin ◽  
Cell Sorting ◽  
Virus Entry ◽  
Skin Explants ◽  
Skin Uptake ◽  
Virus Exposure ◽  
Epidermal Dendritic Cells ◽  
Hiv 1

Macrophage tropic HIV-1 is predominant during the initial viremia after person to person transmission of HIV-1 (Zhu, T., H. Mo, N. Wang, D.S. Nam, Y. Cao, R.A. Koup, and D.D. Ho. 1993. Science. 261:1179–1181.), and this selection may occur during virus entry and carriage to the lymphoid tissue. Human skin explants were used to model HIV-1 selection that may occur at the skin or mucosal surface. Macrophage tropic, but not T cell line tropic strains of HIV-1 applied to the abraded epidermis were recovered from the cells emigrating from the skin explants. Dermis and epidermis were separated by dispase digestion after virus exposure to determine the site of viral selection within the skin. Uptake and transmission to T cells of all HIV-1 isolates was found with the dermal emigrant cells, but only macrophage tropic virus was transferred by emigrants from the epidermis exposed to HIV-1, indicating selection only within the epidermis. CD3+, CD4+ T cells were found in both the dermal and epidermal emigrant cells. After cell sorting to exclude contaminating T cells, macrophage tropic HIV-1 was found in both the dermal emigrant dendritic cells and in dendritic cells sorted from the epidermal emigrants. These observations suggest that selective infection of the immature epidermal dendritic cells represents the cellular mechanism that limits the initial viremia to HIV-1 that can use the CCR5 coreceptor.

scholarly journals Pseudomelanoma diagnostic through confocal microscopy: the challenge of the epidermal dendritic cells

2015 ◽  
Vol 7 (3) ◽  
Author(s):  
Fernanda Berti Rocha Mendes ◽  
Raquel de Paula Ramos Castro ◽  
Mariana Petaccia de Macedo ◽  
Clovis Antonio Lopes Pinto ◽  
João Pedreira Duprat Neto ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Confocal Microscopy ◽  
Epidermal Dendritic Cells

scholarly journals Identification of HIV transmitting CD11c+ human epidermal dendritic cells

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Kirstie M. Bertram ◽  
Rachel A. Botting ◽  
Heeva Baharlou ◽  
Jake W. Rhodes ◽  
Hafsa Rana ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Epidermal Dendritic Cells

scholarly journals Quantitation of Epidermal Dendritic Cells

1984 ◽  
Vol 83 (1) ◽  
pp. 78 ◽  
Author(s):  
Marek Haftek ◽  
Jean Thivolet
Keyword(s):  
Dendritic Cells ◽  
Epidermal Dendritic Cells

Phenotyping of epidermal dendritic cells allows the differentiation between extrinsic and intrinsic forms of atopic dermatitis

2000 ◽  
Vol 143 (6) ◽  
pp. 1193-1198 ◽  
Author(s):  
T. Oppel ◽  
E. Schuller ◽  
S. Günther ◽  
M. Moderer ◽  
J. Haberstok ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Atopic Dermatitis ◽  
Epidermal Dendritic Cells

Decreased density of epidermal dendritic cells in melanocytic naevi

1999 ◽  
Vol 9 (5) ◽  
pp. 521-527 ◽  
Author(s):  
E. Azizi ◽  
A. Schwaaf ◽  
A. Lazarov ◽  
O. Shifer ◽  
A. Lublin ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Melanocytic Naevi ◽  
Epidermal Dendritic Cells
Sign in / Sign up

Export Citation Format

Share Document