In recent decades, increasing attention attracts practitioners role of pathology of different organs and systems of the human body associated with connective tissue dysplasia (DST). The significance of this problem is due to a large prevalence of GOST, system damage, high probability of the formation of different kinds of diseases. Dysplasia of connective tissue (display breach) a violation of the structure of the connective tissue in the embryonic and postnatal periods due to genetically modified extracellular matrix, leading to frustration on tissue homeostasis and organ levels with a progressive course. There have been clinical and neurological examination of 120 patients with neurological manifestations of the syndrome vertebrogenic lumbar spine. Analysis of the results of the clinical study demonstrated that in patients with vertebral syndrome, lumbosacral spine against the background displays GOST significantly (p <0.05) more common protrusion m / s disk changes are more pronounced yellow ties as its thickening. And also more common syndrome joints and vascular dystonia. Significantly (p <0.05) displays GOST (scoliosis, kyphosis, kyphoscoliosis, joints, tendency to dislocation, stretching the ligaments of the joints) - increases the duration of treatment and the severity of pain. The data screening and monitoring of patients in the dynamics of the treatment showed that patients with symptoms GOST significantly (p <0.05) more often aggravation vertebrogenic syndrome lumbosacral spine.
Downregulation of MicroRNA-19b Contributes to Angiotensin II-Induced Overexpression of Connective Tissue Growth Factor in Cardiomyocytes