Lecture of the cycle of specialization in reflexology "Practical application of the theory of U-Sin in traditional Chinese medicine"

The theory of the five elements is widely used in traditional Chinese medicine, and the division of natural phenomena according to the properties of the five elements and the nature of the relationship between them, is practical in clinical acupuncture: to characterize the structural, physiological and pathological features of the patient, diagnosis and treatment. With the development of diseases there is a pathological relationship between Zhang-Fu organs and tissues that they are subordinated to. The human body is an organic whole, in which there are numerous interconnections in the development of the pathological process due to the existing modified interconnections. It is established that the theory of five elements is a simple theory with certain limitations. The laws of the relationship between the elements of the U-Syin cycle are not a reflection of all possible interconnections between the Zhang-Fu organs and the related tissues. In clinical practice, these laws show objective physiological and pathological communications between the internal organs and can be used in the process of acupuncture diagnosis and treatment. The theory of the five elements lies at the heart of the methodology of traditional acupuncture diagnostics, used during its implementation and data analysis, it determines the pathological states in accordance with the characteristics and laws of the relationship of the five elements and formulates the syndromic diagnosis of traditional Chinese Medicine (TCM).

Науково-практична конференція з міжнародною участю «Неврологічні читання (V) пам’яті Панченка Д.І.»

Програма конференції була складена відповідно до тематики НДР кафедри неврології і рефлексотерапії НМАПО імені П.Л. Шупика «Профілактика, діагностика, комплексне лікування та реабілітація захворювань нервової системи з використанням методів рефлексотерапії»: в ній були широко представлені доповіді а також стендові доповіді стосовно питань діагностики та лікування, а також реабілітації найактуальніших неврологічних захворювань, в тому числі таких, що супроводжуються больовим синдромом, а також кардіологічної патології, психічних розладів, захворювань щитовидної залози, ЛОР- органів.

Features of neuroimaging data in patients with chronic cerebral ischemia on the background of angina pectoris

In the article the features of bioelectric activity and magnetic resonance imaging of the brain in patients with chronic cerebral ischemia (CCI) are exposed on the background of stable angina of the voltage ІІ and ІІІ ФК. 90 subjects (61 men and 29 women) (mean age 60.6 ± 7.8 years) were examined in the main group and 30 persons (10 men and 20 women) (mean age 55.2.6 ± 5.5 years) control group aged 45 to 74 years. The analysis of data of the conducted complex neuroimaging examination of patients with ССI on the background of stable angina was collected and provided. Based on the data obtained using neuroimaging techniques, it has been established that in patients with CCI, against the background of stable angina, the course of the disease is associated with the risk of development of the acute cerebrovascular accident.

Comorbidity in cardioneurology

The problem of comorbidity in cardioneurology is one of the urgent problems of modern health care system. When comorbidity main cause of death in the vast majority of patients is cardiovascular and cerebrovascular pathology. The most severe form of disease is stroke. Heart failure - a new epidemic of cardiovascular disease, which manifests itself as one of the major risk factors for stroke.

Metabolic Therapy in hypertensive encephalopathy: emphasis on comorbidity of pathology

The development of primary and repeated disorders of cerebral circulation, vascular dementia, transient ischemic attacks, which are a consequence of the development of acute pathology in patients with hypertensive encephalopathy, lead to a state of persistent disability and disability. Today, the emphasis of treatment is placed on the important role of oxygen deficiency, which leads to the restriction of aerobic energy production due to disturbances in the energy-synthesizing function of the mitochondrial respiratory chain, depletion of endogenous antioxidant stores and activation of lipid peroxidation of cell membranes, leading to death of brain cells. By 2018, a large evidence base for the effectiveness of the use of metabolic therapy in neurology, which takes into account an important factor of the impact of comorbidity of the pathology. The effectiveness of antioxidant therapy in acute and chronic cerebrovascular diseases is confirmed by the fact that the antioxidant improves energy metabolism in the cell, and as a metabolite of the tricarboxylic acid cycle (succinate, which provides pronounced antioxidant and antihypoxic properties) has a positive effect on the main links of pathogenesis of diseases associated with processes freely Radical oxidation. It is proved that the preparation of Mexicor reduces the manifestation of oxidative stress, inhibits free radical peroxide oxidation of lipids, improves cellular energy metabolism, activates the energy-synthesizing functions of mitochondria, enhances compensatory activation of aerobic glycolysis and reduces the degree of inhibition of oxidative processes in the Krebs cycle. The drug Mexocor has a wide spectrum of pharmacological action, which allows it to be used successfully in acute and chronic cerebrovascular diseases, accompanied by vascular comorbidity.

The influence of the autonomic nervous system in the development of chronic heart failure in patients with chronic brain ischemia combined with myocardial infarction

Heart failure - severe, common clinical syndrome that is the result of many heart diseases is progressive, significantly reduces the life expectancy of patients and impairs its quality. Leading nosological forms the structure of coronary heart disease for many years, is a myocardial infarction. Growing proportion of elderly in most populations, increased survival after acute myocardial infarction (AMI) resulted in a significant increase in the number of patients with chronic heart failure (CHF). Increased tone of the sympathetic division precedes the development of chronic cerebral ischemia and, therefore, may complicate the course of disease in the presence of chronic heart failure.

Sleep disorders in patients with multiple sclerosis

Studied sleep disorders (SD) in patients with multiple sclerosis (MS) using a Severity scale of insomnia (ІSІ) and Sleepiness Scale Epworth (ESS) in comparison with the control groups and in the aspect of comorbidity, as well as to determine the correlations between the SD and the degree of disability, the level of severity of fatigue, depression, pain, quality of life (QOL). The study involved 207 MS patients with different forms of cours and 109 people who constituted the control group. Evaluated the clinical and demographic characteristics of the patients with MS due to comorbidity, determines the level of disability (EDSS), severity of pain (VAS), the severity of fatigue (FSS), depression (BDI-II), indicators of QOL (SF-36). Single or multiple co-morbidities found in 102 (49.3%) patients with MS, there was no co-morbidities in 105 (50.7%) patients with MS. It was found that more often among the SD in the study group of patients with MS observed insomnia (54.1%). It led to a decrease in the total duration of a night's sleep, as well as mainly predispose hypersomnia (43.0%). Also found that patients with MS I and II groups SD were significantly more likely than the control groups. It is shown that in patients with MS II group have a more severe manifestations of insomnia and daytime sleepiness (DS), which is associated with the presence of comorbid disease. According to the correlation analysis shows that the degree of the SD in patients with MS is closely correlated with the level of fatigue were also observed close correlation between insomnia and DS.

Painful Syndromes: Mechanisms of Nociception and Antinociception

Traditionally, two main concepts are considered in the views on morphophysiological bases of pain. The first concept suggests that the skin has pain receptors, from which begin the specific afferent pathways to the brain, where there are special centers for the treatment of pain information. Another concept put forward by the Goldscheider is a non-specific pain theory, or a theory of intensity, a «pattern» according to which any sensory stimulus that reaches a certain intensity can cause pain. That is, specific pain structures do not exist, and pain is the result of a combination of thermal, mechanical and other sensory stimuli.

Multiple sclerosis: clinical and pathogenetic characteristics and therapeutic approaches based on comorbidity

The research is dedicated to studying the clinical, neurophysiological, neuroimaging, neuropsychological, immunopathological manifestations of MS on the background of comorbid pathology, evaluation of complex treatment.The features of the manifestations of fatigue, depression, pain, cognitive impairment, sleep disorders in patients with MS based on comorbidity and impact of violations on the quality of life. On the basis of the study of risk factors, the analysis revealed the features of development of MS in conditions of comorbid pathology. Based on the factors studied, a pathogenetic model of the character of the effect of comorbidity on the course of MS with regard to prognostic signs for clinical, psychoemotional, neurophysiological and neuroimaging indicators has been created, and it is possible to individually assess the risk of development and progression of MS. Efficacy and comparative analysis of the use of complex (medicaments and non-medicaments) treatment was revealed, the frequency of exacerbations decreased and the effect on the course of the disease with MS taking into account the comorbid pathology and heterogeneity of clinical-neurological and psychoemotional disorders, clinical, neuropsychological, neuroimaging, neuroimaging signs of disease activity.

Investigation of SWI - basal nucleus intensity and fractional anisotropy of cerebral pathways in patients with chronic cerebral ischemia

Mild parkinsonian signs (MPS) and cognitive decline are common symptoms of small vessel disease (SVD), and are associated with reduced life quality and duration. There is a probable relationship between the neuroimaging features and SVD symptoms. Objective of this study was to identify whether there is an association between SWI basal nucleus hypointensity, fractional anisotropy and SVD symptoms such as cognitive decline and MPS.