A Man with Shortness of Breath, Weight Loss, and Night Sweats

1989 ◽  
pp. 16-33
Author(s):  
Michael F. Para
The Lancet ◽  
2012 ◽  
Vol 380 (9843) ◽  
pp. 726-727 ◽  
Author(s):  
D Dahdaleh ◽  
DM Altmann ◽  
O Malik ◽  
RS Nicholas
Keyword(s):  

2005 ◽  
Vol 49 (2) ◽  
pp. 319-322 ◽  
Author(s):  
Ludimyla H.F. Meister ◽  
Patrícia R. Hauck ◽  
Hans Graf ◽  
Gisah A. Carvalho

A 26-year-old pregnant woman presenting with repeated episodes of vaginal bleeding, weight loss, and shortness of breath was diagnosed with choriocarcinoma with metastases to both lungs. Chorionic gonadotropin levels (hCG) were >2.5 x 10(6)mU/mL. Consistent with hCG-induced subclinical hyperthyroidism, she had a suppressed TSH of 0.037mU/L (0.49 - 4.67), a T4 of 18.1µg/dL (4.9 - 10.7), and T3 of 136ng/dL (45 - 137). Chemotherapy with a combined regimen with etoposide, methotrexate, and dactinomycine was started. The initial course was complicated by urosepsis with respiratory distress requiring endotracheal intubation for 3 days. She then improved rapidly, and her thyroid function tests were within normal limits by day 12. Six months later, after ten cycles of chemotherapy, the patient was in remission without signs of residual tumor or hCG-induced paraneoplastic activity.


1986 ◽  
Vol 67 (3) ◽  
pp. 211-212
Author(s):  
V. M. Andreev ◽  
P. N. Aliakberova ◽  
V. A. Belyakov

T., 39 years old, considers herself ill since the beginning of 1983. She had a severe cough, at first dry, later with mucopurulent sputum. During the year she was treated as an outpatient, taking antibiotics and cough pills. In December 1983, she was admitted to a hospital in Kazan, but her condition did not improve. In spring 1984 her cough sharply intensified again, body temperature increased, amount of sputum increased, shortness of breath, which at times became suffocation, general weakness, sweating, poor appetite and weight loss became disturbing. Past illnesses: measles, scarlet fever.


2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S131-S131
Author(s):  
Dongpo Salas ◽  
Xing Zhao ◽  
Stephen Cavalieri

Abstract Mycobacterium chimaera (MCH) is a non-tuberculous mycobacterium commonly found in the environment. It is a member of the M. avium complex (MAC), and rarely causes infections in humans. However, invasive MCH infections have been reported associated with heater-cooler devices during cardiac surgery. Detection of MCH infections in this setting has been impeded by inadequate clinical awareness and laboratory tests. A 77-year-old man had aorta valve replacement 3 years ago. He recently presented with constitutional symptoms, including fatigue, night sweats, and 50 pounds of weight loss. PET CT showed ground-glass and nodular opacities in the lungs. Bone marrow biopsy demonstrated noncaseating granulomas. Transesophageal echocardiogram revealed severe stenosis and regurgitation of aortic valves. Despite antibiotics and heart surgery to relieve stenosis, the patient succumbed. Autopsy showed multiple small granulomas in the lung and multifocal chronic inflammation in the heart. Premortem mycobacterial cultures of aortic valves were performed, which grew MAC by DNA probe in 1 week. Subsequently, it was identified as MCH by sequencing of the ITS1/ITS2 region. The cause of death was heart failure due to MCH endocarditis. MCH infection is rare but potentially fatal if not promptly treated. Therefore, it is critical to identify patients at risk for infection. Since 2013, over 100 cases of MCH endocarditis have been reported worldwide, specifically associated with contaminated heater-cooler units during heart surgery. Characteristically, MCH infection has a long incubation period after exposure (median 17 months, range 3-72 months). Signs and symptoms are generally nonspecific and often include fatigue, fever, and weight loss. The risk of MCH infection in patients undergoing open heart surgery is low, but clinicians should be aware of the risks especially when heater-cooler units are utilized. A close follow-up over a long period may be necessary due to the long incubation period of this infection.


2007 ◽  
Vol 86 (7) ◽  
pp. 412-413 ◽  
Author(s):  
Eimear Phelan ◽  
Emer Lang ◽  
Peter Gormley ◽  
John Lang

Cervical lymphadenopathy has many underlying etiologies. One of its rare causes is Kikuchi-Fujimoto disease (Kikuchi's disease, histiocytic necrotizing lymphadenitis). We discovered such a cause in a 37-year-old woman who had presented with malaise, night sweats, and weight loss in addition to cervical lymphadenopathy. We based our diagnosis on excisional lymph node biopsy. We also review 2 other cases of Kikuchi's disease that were diagnosed by others at our institution. Clinically and histologically, Kikuchi's disease is very similar to lymphoma, and distinguishing the two is difficult. However, despite the fact that Kikuchi's disease is benign, an accurate diagnosis is important because misdiagnosis might lead to unnecessary surgery and/or chemotherapy.


2020 ◽  
Vol 38 (8) ◽  
pp. 392-393
Author(s):  
Carlos A. Andrade-Castellanos ◽  
Beatriz A. Paz-Velarde ◽  
Elsa E. Carreón-Bautista ◽  
Luis I. Pozos-Ochoa
Keyword(s):  

Author(s):  
Carlos A. Andrade-Castellanos ◽  
Beatriz A. Paz-Velarde ◽  
Elsa E. Carreón-Bautista ◽  
Luis I. Pozos-Ochoa
Keyword(s):  

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Mukesh Thawani ◽  
Elizabeth Hale ◽  
Eyassu Habte-Gabr

Skeletal tuberculosis (TB) accounts for about 1–2% of all TB cases and 10% of extrapulmonary TB cases. We present a 19-year-old male with multifocal tubercular osteomyelitis, who presented with progressively worsening back pain, weight loss, fatigue, anorexia, decreased mobility, low-grade fever, and night sweats—but without pulmonary involvement.


2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Tharindu Vithanage ◽  
Gerben Keijzers ◽  
Nicola Jane Willis ◽  
Tara Cochrane ◽  
Linda Smith

Respiratory failure due to subglottic stenosis is a rare but serious condition. A 22-year-old male presented to the emergency department (ED) with shortness of breath, stridor, and change in tone of voice. The patient did not complain of B-symptoms (fever, weight loss, and night sweats). In the week before this presentation, he was diagnosed with an upper respiratory tract infection with associated bronchospasm and discharged on oral antibiotics and inhaled salbutamol without effect. He developed hypercapnic respiratory failure in the ED after a coughing episode. A normal nasopharyngoscopic examination and a subtle mediastinal abnormality on chest radiograph lead to a working diagnosis of retrosternal subglottic obstruction. The complexities of his airway management and suggestions for multidisciplinary approach are discussed.


2021 ◽  
pp. 515
Author(s):  
Ernawati Ernawati ◽  
Andreas Adiwinata Then ◽  
Irwan Surya Angkasa ◽  
Kevina Liora ◽  
Yuli Nursela

Background: Tuberculosis (TB) is an infectious disease caused by TB bacteria (Mycobacterium Tuberculosis), where most of the TB bacteria attack the lungs, but can also affect other body organs. Based on data from WHO in 2020 in Southeast Asia, Tuberculosis sufferers are estimated to reach 4.3 million and around 632,000 people died from this disease. The estimated number of tuberculosis cases in Indonesia in 2020 is 845,000 cases with the number of deaths caused by this disease as many as 13,947 cases. In Tangerang district there were 6,089/100,000 new tuberculosis cases detected. The symptoms such as a persistent cough that lasts more than 3 weeks and usually brings up phlegm, which may be bloody, weight loss, night sweats, high temperature, tiredness and fatigue, loss of appetite, swellings in the neck.The purpose of this devotional activity is to increase the knowledge of tuberculosis and the way to prevent for the community in the working area of Legok Health Center.This method of devotion is done by collecting data through pre-tests before extension activities and workshops and then post test after activities. The data obtained is processed statistically. Counseling is an extension on tuberculosis prevention efforts and workshops on how to ethically cough and the use of good and correct masks to the community in the work area of Legok Health Center.Results data processing results from pre-test, post-test and education about TB prevention efforts obtained post-test values >70 in 95% of respondents with an average value of 85.5. The results of cough ethics workshops and the use of masks 100% participants can be accompanied by the distribution of masks.Conclusion after counseling and workshops there is an increase in knowledge and ability to perform cough ethics and the use of masks that are good and correct. This effort can be done continuously so that the goal of reducing the incidence of tuberculosis can be achieved.Latar belakang tuberkulosis (TB) merupakan penyakit menular yang disebabkan oleh kuman TB (Mycobacterium Tuberculosis), dimana sebagian besar kuman TB menyerang paru-paru, tetapi dapat juga mengenai organ tubuh lainnya. Berdasarkan data WHO tahun 2020 di Asia Tenggara penderita tuberkulosis diperkirakan mencapai 4,3 juta dan sekitar 632.000 orang meninggal diakibatkan penyakit ini. Estimasi kasus tuberkulosis di Indonesia pada tahun 2020 sebanyak 845.000 kasus dengan jumlah kematian yang diakibatkan oleh penyakit ini sebanyak 13.947 kasus. Pada kabupaten Tangerang terdapat 6.089/100.000 kasus tuberkulosis baru yang terdeteksi. Penyakit ini menimbulkan berbagai gejala seperti: Batuk >3 minggu terkadang bercampur darah, penurunan berat badan, berkeringat malam hari, demam dan mengigil, lemas, penurunan nafsu makan, pembengkakn di sekitar leher.Tujuan dari kegiatan pengabdian ini untuk meningkatkan penegtahuan tentang tuberkulosis dan cara-cara pencegahannya di wilayah kerja Puskesmas Legok.Metode pengabdian ini dilakukan dengan pengumpulan data melalui pre test saat sebelum kegiatan penyuluhan dan workshop kemudian post test setelah kegiatan. Data yang diperoleh diolah secara statistik. Penyuluhan yang dilakukan adalah penyuluhan tentang upaya pencegahan tuberkulosis dan workshop cara etikda batuk serta penggunaan masker yang baik dan benar kepada masyarakat di wilayah kerja Puskesmas Legok.Hasil pengolahan data dari pre-test, post-test dan edukasi mengenai upaya pencegahan TB diperoleh nilai post-test nilainya >70 pada 95% responden dengan nilai rerata 85,5. Hasil workshop etika batuk dan penggunaan masker 100% peserta dapat disertai dengan pembagian masker. Kesimpulan setelah dilakukan penyuluhan dan workshop terjadi peningkatan pengetahuan dan kemampuan melakukan etika batuk dan penggunaan masker yang baik dan benar. Upaya ini dapat dilakukan secara berkesinambungan agar tujuan menurunkan angka kejadian tuberkulosis dapat dicapai.


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