Reactive Oxygen-Induced Modifications of Cardiac Electrophysiology: A Comparison of the Effects of Rose Bengal and other Reactive Oxygen Generators

1993 ◽  
pp. 267-284 ◽  
Author(s):  
Merrill Tarr ◽  
Dennis P. Valenzeno
Keyword(s):  
Rose Bengal ◽  
Cardiac Electrophysiology ◽  
Reactive Oxygen

Role of reactive oxygen species in cardiac preconditioning: Study with photoactivated rose bengal in isolated rat hearts

2000 ◽  
Vol 33 (4) ◽  
pp. 393-405 ◽  
Author(s):  
M.-C. Toufektsian ◽  
S. Tanguy ◽  
A. Jeunet ◽  
J.G. de Leiris ◽  
F.R. Boucher
Keyword(s):  
Reactive Oxygen Species ◽  
Rose Bengal ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Rat Hearts ◽  
Cardiac Preconditioning ◽  
Isolated Rat

scholarly journals Investigating the reactive oxygen species production of Rose Bengal and Merocyanine 540-loaded radioluminescent nanoparticles

2021 ◽  
Vol 3 (5) ◽  
pp. 1375-1381
Author(s):  
Anne Nsubuga ◽  
Gabrielle A. Mandl ◽  
John A. Capobianco
Keyword(s):  
Reactive Oxygen Species ◽  
Mesoporous Silica ◽  
Rose Bengal ◽  
Reactive Oxygen Species Production ◽  
Reactive Oxygen ◽  
Type I ◽  
Oxygen Species ◽  
Merocyanine 540 ◽  
Species Production

Mesoporous silica-coated NaLuF4:Dy3+,Gd3+ radioluminescent nanoparticles were loaded with photosensitizers – Rose Bengal and Merocyanine 540. ABDA, DPBF, NaN3 and EPR assays were used to determine that a type I mechanism was prevalent for this X-PDT nanosystem.

scholarly journals XANTHENE DYES-MEDIATED IN VITRO PHOTODYNAMIC TREATMENT OF CANCER AND NON-CANCER CELL LINES

2021 ◽  
Vol 50 (3) ◽  
pp. 114-121
Author(s):  
Lukáš Malina ◽  
Kateřina Bartoň Tománková ◽  
Barbora Hošíková ◽  
Jana Jiravová ◽  
Jakub Hošík ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Cell Lines ◽  
Rose Bengal ◽  
Antimicrobial Agents ◽  
Reactive Oxygen ◽  
In Vitro Tests ◽  
Oxygen Species ◽  
Xanthene Dyes ◽  
Erythrosin B

Rose bengal and erythrosin B are xanthene dyes mainly known and used as antimicrobial agents, but due to their photodynamic activity they are also potential photosensitizers for cancer photodynamic therapy. The aim of this work is to study a photodynamic efficacy of rose bengal and erythrosin B against human skin melanoma and mouse fibroblast cell lines, compare them with each other and find out their photodynamic properties induced by light emitting diodes with total light dose of 5 J/cm2. To fully identify and understand photodynamic properties of both potentially effective photosensitizers, a set of complex in vitro tests such as cell cytotoxic assay, measurement of reactive oxygen species production, mitochondrial membrane potential change assay, mode of cell death determination or comet assay were made. Although both photosensitizers proved to have similar properties such as increasing production of reactive oxygen species with the higher concentration, predominance of necrotic mode of death or genotoxicity, the more effective photosensitizer was rose bengal because its EC50 was over 20 times lower for both cell lines than in case of erythrosin B.  

scholarly journals Blue light triggered generation of reactive oxygen species from silica coated Gd3Al5O12:Ce3+ nanoparticles loaded with rose Bengal

Data in Brief ◽  
2018 ◽  
Vol 20 ◽  
pp. 1023-1028 ◽  
Author(s):  
Akhil Jain ◽  
Rina Koyani ◽  
Carlos Muñoz ◽  
Prakhar Sengar ◽  
Oscar E. Contreras ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Blue Light ◽  
Rose Bengal ◽  
Reactive Oxygen ◽  
Oxygen Species

3-Dimensional immunolabeling and in situ hybridization detection using fluorescence photooxidation and intermediate-voltage Electron Microscopy

1994 ◽  
Vol 52 ◽  
pp. 164-165
Author(s):  
Thomas J. Deerinck ◽  
Maryann E. Martone ◽  
Varda Lev-Ram ◽  
David P. L. Green ◽  
Roger Y. Tsien ◽  
...  
Keyword(s):  
Laser Scanning ◽  
Reactive Oxygen ◽  
Confocal Laser Scanning Microscope ◽  
Fluorescent Dye ◽  
Confocal Laser ◽  
3 Dimensional ◽  
Voltage Electron ◽  
Dimensional Distribution ◽  
Electron Microscopes ◽  
New Generation

The confocal laser scanning microscope has become a powerful tool in the study of the 3-dimensional distribution of proteins and specific nucleic acid sequences in cells and tissues. This is also proving to be true for a new generation of high contrast intermediate voltage electron microscopes (IVEM). Until recently, the number of labeling techniques that could be employed to allow examination of the same sample with both confocal and IVEM was rather limited. One method that can be used to take full advantage of these two technologies is fluorescence photooxidation. Specimens are labeled by a fluorescent dye and viewed with confocal microscopy followed by fluorescence photooxidation of diaminobenzidine (DAB). In this technique, a fluorescent dye is used to photooxidize DAB into an osmiophilic reaction product that can be subsequently visualized with the electron microscope. The precise reaction mechanism by which the photooxidation occurs is not known but evidence suggests that the radiationless transfer of energy from the excited-state dye molecule undergoing the phenomenon of intersystem crossing leads to the formation of reactive oxygen species such as singlet oxygen. It is this reactive oxygen that is likely crucial in the photooxidation of DAB.

Mitochondria as a source of reactive oxygen species

2009 ◽  
pp. c3 ◽  
Author(s):  
Helena M. Cochemé ◽  
Michael P. Murphy
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Oxygen Species
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