Actions of Insecticides in Mammalian Central Nervous System — Use of in Vivo Hippocampal Evoked Potentials

1989 ◽  
pp. 115-137
Author(s):  
T. E. Albertson ◽  
R. M. Joy
Life Sciences ◽  
1982 ◽  
Vol 31 (20-21) ◽  
pp. 2343-2346 ◽  
Author(s):  
W. Zieglgänsberger ◽  
E.D. French ◽  
N. Mercuri ◽  
F. Pelayo ◽  
J.T. Williams

1968 ◽  
Vol 29 (1) ◽  
pp. 20-37 ◽  
Author(s):  
Raoul DiPerri ◽  
Anant Dravid ◽  
Arlene Schweigerdt ◽  
Harold E. Himwich

2018 ◽  
Vol 16 (S1) ◽  
pp. S55-S64
Author(s):  
G. Hajjaj ◽  
A. Bahlouli ◽  
M. Tajani ◽  
K. Alaoui ◽  
Y. Cherrah ◽  
...  

Ormenis mixta L. is traditionally used for central nervous system (CNS)-related diseases. Its anti-stress properties have received attention in Moroccan traditional medicine and aromatherapy. However, no pharmacological studies have yet been undertaken on this plant in Morocco. The present study provides a preliminary phytochemical screening and psychopharmacological profile of the essential oil and aqueous extract from Ormenis mixta L. by using behavioral tests in vivo, at graded doses. The result of this research shows that Ormenis mixta L. was safe up to 2 g/kg b.w. (body weight) in the acute toxicity study, possesses potential psychostimulant effect, and has antianxiety and antidepressant-like activity. This activity profile of Ormenis mixta L. was similar to the typical psychostimulant, caffeine. The exact mechanism of action underlying this stimulant-like effect should be clarified with further detailed studies. These results explained the extensive use of Ormenis mixta L. as a traditional medicine in Morocco.


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