Organization of Dorsal Horn Neurotransmitter Systems

Spinal Afferent Processing ◽

10.1007/978-1-4684-4994-5_5 ◽

1986 ◽

pp. 97-116 ◽

Cited By ~ 9

Author(s):

Carole C. LaMotte

Keyword(s):

Dorsal Horn ◽

Neurotransmitter Systems

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Basic Research Strategies for Imaging Neurotransmitter Systems

PsycEXTRA Dataset ◽

10.1037/e496752006-002 ◽

1986 ◽

Author(s):

Solomon H. Snyder ◽

Keyword(s):

Basic Research ◽

Research Strategies ◽

Neurotransmitter Systems

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Effect of chronic hypoxia exposure to noxious stimulation-induced c-fos expression in the trigeminal spinal nucleus caudalis and the first cervical dorsal horn

Neuroscience Research ◽

10.1016/s0168-0102(00)81513-8 ◽

2000 ◽

Vol 38 ◽

pp. S111

Author(s):

T Tanimoto

Keyword(s):

Dorsal Horn ◽

Chronic Hypoxia ◽

Noxious Stimulation ◽

Hypoxia Exposure ◽

Fos Expression ◽

Spinal Nucleus

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Modulating Effect of Peptide Semax on the Level of Synaptic Activity and Short-Term Plasticity in Glutamatergic Synapses of Co-Cultured Dorsal Root Ganglion and Dorsal Horn Neurons of Rats

International Journal of Physiology and Pathophysiology ◽

10.1615/intjphyspathophys.v7.i3.90 ◽

2016 ◽

Vol 7 (3) ◽

pp. 263-272

Author(s):

Mariia S. Shypshyna ◽

Mycola S. Veselovsky ◽

Nikolai F. Myasoedov ◽

Stanislav I. Shram ◽

Svetlana A. Fedulova

Keyword(s):

Dorsal Root Ganglion ◽

Dorsal Horn ◽

Dorsal Root ◽

Synaptic Activity ◽

Glutamatergic Synapses ◽

Short Term ◽

Short Term Plasticity ◽

Dorsal Horn Neurons

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Single Intraperitoneal Injection of Low-Dose Ketamine Pretreatment Alleviates Mechanical Hyperalgesia and Downregulates the Expression of Inflammatory Cytokines in Spinal Dorsal Horn of Rats

Journal of Anesthesia and Perioperative Medicine ◽

10.24015/japm.2015.0032 ◽

2015 ◽

Vol 2 (5) ◽

pp. 236-243

Author(s):

Li Xu ◽

Yu Shen ◽

Lin Liu ◽

Yin Cui ◽

Xiao-Ping Gu ◽

...

Keyword(s):

Dorsal Horn ◽

Inflammatory Cytokines ◽

Intraperitoneal Injection ◽

Spinal Dorsal Horn ◽

Low Dose ◽

Mechanical Hyperalgesia ◽

Spinal Dorsal ◽

Single Intraperitoneal Injection

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Faculty Opinions recommendation of Spread of excitation across modality borders in spinal dorsal horn of neuropathic rats.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1105023.561186 ◽

2008 ◽

Author(s):

Nanna Finnerup

Keyword(s):

Dorsal Horn ◽

Spinal Dorsal Horn ◽

Spinal Dorsal ◽

Spread Of Excitation

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Faculty Opinions recommendation of Substance P receptor-expressing dorsal horn neurons: lessons from the targeted cytotoxin, substance P-saporin.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1108493.564556 ◽

2008 ◽

Author(s):

Anthony Dickenson

Keyword(s):

Substance P ◽

Dorsal Horn ◽

Dorsal Horn Neurons ◽

Substance P Receptor

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Faculty Opinions recommendation of Innocuous, not noxious, input activates PKCgamma interneurons of the spinal dorsal horn via myelinated afferent fibers.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1120062.576194 ◽

2008 ◽

Author(s):

Nanna Finnerup

Keyword(s):

Dorsal Horn ◽

Spinal Dorsal Horn ◽

Spinal Dorsal ◽

Afferent Fibers

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Faculty Opinions recommendation of Activation of glia and microglial p38 MAPK in medullary dorsal horn contributes to tactile hypersensitivity following trigeminal sensory nerve injury.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.30481.486982 ◽

2006 ◽

Author(s):

Barry Sessle

Keyword(s):

Dorsal Horn ◽

Nerve Injury ◽

P38 Mapk ◽

Sensory Nerve ◽

Medullary Dorsal Horn

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Influence of intrathecal injection of p38 MAPK inhibitor on BDNF expression in dorsal horn of spinal cord of rats with neuropathic pain

Academic Journal of Second Military Medical University ◽

10.3724/sp.j.1008.2010.00883 ◽

2010 ◽

Vol 30 (8) ◽

pp. 883-886

Author(s):

Xiao-di YAN ◽

Qian-bo CHEN ◽

Shuang-qiong ZHOU ◽

Hong-bin YUAN

Keyword(s):

Spinal Cord ◽

Neuropathic Pain ◽

Dorsal Horn ◽

P38 Mapk ◽

Intrathecal Injection ◽

Bdnf Expression ◽

P38 Mapk Inhibitor ◽

Mapk Inhibitor

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Dorsal Horn Pain Mechanisms

The Oxford Handbook of the Neurobiology of Pain ◽

10.1093/oxfordhb/9780190860509.013.23 ◽

2019 ◽

pp. 444-469 ◽

Cited By ~ 1

Author(s):

Hanns Ulrich Zeilhofer ◽

Robert Ganley

Keyword(s):

Dorsal Horn ◽

Neuronal Excitability ◽

Functional Organization ◽

Synaptic Integration ◽

Synaptic Efficacy ◽

Pain Mechanisms ◽

Pain Pathway ◽

Pathological Pain ◽

The Subject ◽

Equivalent Structure

The spinal dorsal horn and its equivalent structure in the brainstem constitute the first sites of synaptic integration in the pain pathway. A huge body of literature exists on alterations in spinal nociceptive signal processing that contribute to the generation of exaggerated pain states and hence to what is generally known as “central sensitization.” Such mechanisms include changes in synaptic efficacy or neuronal excitability, which can be evoked by intense nociceptive stimulation or by inflammatory or neuropathic insults. Some of these changes cause alterations in the functional organization of dorsal horn sensory circuits, leading to abnormal pathological pain sensations. This article reviews the present state of this knowledge. It does not cover the contributions of astrocytes and microglia in detail as their functions are the subject of a separate chapter.

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