Ion Channels in T Lymphocytes

1987 ◽  
pp. 85-101 ◽  
Author(s):  
Michael D. Cahalan ◽  
K. George Chandy ◽  
Thomas E. DeCoursey ◽  
Sudhir Gupta ◽  
Richard S. Lewis ◽  
...  
Keyword(s):  
Ion Channels ◽  
T Lymphocytes

Novel Inhibitors of Potassium Ion Channels on Human T Lymphocytes

1995 ◽  
Vol 38 (11) ◽  
pp. 1877-1883 ◽  
Author(s):  
William F. Michne ◽  
Joseph W. Guiles ◽  
Adi M. Treasurywala ◽  
Laurie A. Castonguay ◽  
Carolyn A. Weigelt ◽  
...  
Keyword(s):  
Ion Channels ◽  
T Lymphocytes ◽  
Potassium Ion ◽  
Potassium Ion Channels ◽  
Human T Lymphocytes

Anuroctoxin, a New Scorpion Toxin of the α-KTx 6 Subfamily, Is Highly Selective for Kv1.3 over IKCa1 Ion Channels of Human T Lymphocytes

2004 ◽  
Vol 67 (4) ◽  
pp. 1034-1044 ◽  
Author(s):  
Miklós Bagdáany ◽  
Cesar V. F. Batista ◽  
Norma A. Valdez-Cruz ◽  
Sándor Somodi ◽  
Ricardo C. Rodriguez de la Vega ◽  
...  
Keyword(s):  
Ion Channels ◽  
T Lymphocytes ◽  
Scorpion Toxin ◽  
Human T Lymphocytes

The Multiple Roles of ATP-Gated P2(X) Ion Channels in T Lymphocytes

Messenger ◽  
2015 ◽  
Vol 4 (1) ◽  
pp. 67-81 ◽  
Author(s):  
Friedrich Haag ◽  
Stephan Menzel ◽  
Sana Javed ◽  
Anne Rissiek ◽  
Sahil Adriouch ◽  
...  
Keyword(s):  
Ion Channels ◽  
T Lymphocytes ◽  
Multiple Roles

scholarly journals The effect of lentinan on the gene expression of major ion channels in T lymphocytes isolated from mice exposed to chronic radiation

2013 ◽  
Vol 28 (2) ◽  
pp. 204-211 ◽  
Author(s):  
Qing-Jie Fu ◽  
Yong Wang ◽  
Ying-Hua Liu ◽  
Ping-Ping Lin ◽  
Pei-Pei Wang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Ion Channels ◽  
T Lymphocytes ◽  
Real Time Pcr ◽  
Radiation Effects ◽  
Expression Profiles ◽  
Protective Effects ◽  
Radiation Stress ◽  
Chronic Radiation ◽  
Murine Spleen

It is known that Kv1.3, KCa3.1, CRAC, TRPM7, and Clswell are five important ion channels in T lymphocytes. To investigate the mechanism underlying the protective effects of lentinan against T lymphocytes injury induced by chronic radiation in mice, we determined the expression profiles of Kv1.3, KCa3.1, Orai1, STIM1, TRPM7, and Clswell genes. Mice were injected with different concentrations of lentinan before exposure to 60Co g-ray. Total RNA was then extracted from T lymphocytes in murine spleen. The Real time-PCR was per- formed to detect the expression levels of Kv1.3, KCa3.1, Orai1, STIM1, TRPM7, and Clswell genes. The results show that, out of the six ion channels gene expression detected in the present study, only Kv1.3 and Orai1 were altered by lentinan in mice under chronic radiation stress. Kv1.3 and Orai1 expression were significantly elevated in T-lymphocytes isolated from irradiated mice, and were normalized by lentinan treatment. Our results suggest that that Kv1.3 and Orai1 channels may mediate the anti-radiation effects of lentinan.

scholarly journals The functional network of ion channels in T lymphocytes

2009 ◽  
Vol 231 (1) ◽  
pp. 59-87 ◽  
Author(s):  
Michael D. Cahalan ◽  
K. George Chandy
Keyword(s):  
Ion Channels ◽  
T Lymphocytes ◽  
Functional Network

Voltage-dependent ion channels in T-lymphocytes

1985 ◽  
Vol 10 (1) ◽  
pp. 71-95 ◽  
Author(s):  
T.E. DeCoursey ◽  
K.G. Chandy ◽  
S. Gupta ◽  
M.D. Cahalan
Keyword(s):  
Ion Channels ◽  
T Lymphocytes ◽  
Voltage Dependent

Autologous T lymphocytes recognize the tumour-derived immunoglobulin VH-CDR3 region in patients with B-cell chronic lymphocytic leukaemia

2000 ◽  
Vol 111 (1) ◽  
pp. 230-238 ◽  
Author(s):  
Mohammad Reza Rezvany ◽  
Mahmood Jeddi-Tehrani ◽  
Hodjattallah Rabbani ◽  
Ulla Ruden ◽  
Lennart Hammarstrom ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Chronic Lymphocytic Leukaemia ◽  
B Cell ◽  
Lymphocytic Leukaemia ◽  
Cell Chronic Lymphocytic Leukaemia ◽  
Cdr3 Region
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