Cloning and Characterization of New Alcohol Dehydrogenase and Aldehyde Dehydrogenase Isozymes

Alcoholism ◽  
1991 ◽  
pp. 95-99
Author(s):  
A. Yoshida ◽  
L. Hsu ◽  
M. Yasunami
Keyword(s):  
Alcohol Dehydrogenase ◽  
Aldehyde Dehydrogenase

Cloning and characterization of an aldehyde dehydrogenase gene GmALDH3-1 from soybean

2010 ◽  
Vol 32 (5) ◽  
pp. 492-497 ◽  
Author(s):  
Fang HUANG ◽  
Ying-Jun CHI ◽  
Hui HE ◽  
De-Yue YU
Keyword(s):  
Aldehyde Dehydrogenase ◽  
Dehydrogenase Gene

scholarly journals Organization and characterization of the rat class 3 aldehyde dehydrogenase gene

1993 ◽  
Vol 268 (17) ◽  
pp. 12530-12536 ◽  
Author(s):  
D.C. Asman ◽  
K. Takimoto ◽  
H.C. Pitot ◽  
T.J. Dunn ◽  
R. Lindahl
Keyword(s):  
Aldehyde Dehydrogenase ◽  
Dehydrogenase Gene

Thermodynamics of Adsorption of Alcohol Dehydrogenase on Gold Nanoparticle Surface: A Model Based Analysis Versus Direct Measurement

2021 ◽  
Author(s):  
Akriti Mishra ◽  
Kamini Mishra ◽  
Dipayan Bose ◽  
Abhijit Chakrabarti ◽  
Puspendu Kumar Das
Keyword(s):  
Alcohol Dehydrogenase ◽  
Gold Nanoparticle ◽  
Protein Interaction ◽  
Protein Corona ◽  
Quality Data ◽  
Nanoparticle Surface ◽  
Tremendous Importance ◽  
Good Quality Data ◽  
Model Based Analysis

Characterization of nanoparticle protein corona has gained tremendous importance lately. The parameters which quantitatively establish a specific nanoparticle-protein interaction need to be measured accurately since good quality data is necessary...

scholarly journals Genetic and biochemical characterization of a short-chain alcohol dehydrogenase from the hyperthermophilic archaeon Pyrococcus furiosu s

2001 ◽  
Vol 268 (10) ◽  
pp. 3062-3068 ◽  
Author(s):  
John van der Oost ◽  
Wilfried G. B. Voorhorst ◽  
Servé W. M. Kengen ◽  
Ans C. M. Geerling ◽  
Vincent Wittenhorst ◽  
...  
Keyword(s):  
Alcohol Dehydrogenase ◽  
Biochemical Characterization ◽  
Short Chain ◽  
Chain Alcohol ◽  
Hyperthermophilic Archaeon ◽  
Short Chain Alcohol

scholarly journals Characterization of a Stem-like Subpopulation in Basal-like Ductal Carcinoma in Situ (DCIS) Lesions

2013 ◽  
Vol 289 (3) ◽  
pp. 1303-1312 ◽  
Author(s):  
Qinglin Li ◽  
Gabriel Eades ◽  
Yuan Yao ◽  
Yongshu Zhang ◽  
Qun Zhou
Keyword(s):  
Cancer Cells ◽  
Aldehyde Dehydrogenase ◽  
Breast Cancer Cells ◽  
Ductal Carcinoma ◽  
Chemopreventive Agent ◽  
Aldehyde Dehydrogenase 1 ◽  
Aldh1 Expression ◽  
Migration Potential

Previously, we found that basal-like ductal carcinoma in situ (DCIS) contains cancer stem-like cells. Here, we characterize stem-like subpopulations in a model of basal-like DCIS and identify subpopulations of CD49f+/CD24− stem-like cells that possess aldehyde dehydrogenase 1 activity. We found that these cells show enhanced migration potential compared with non-stem DCIS cells. We also found that the chemopreventive agent sulforaphane can target these DCIS stem-like cells, reduce aldehyde dehydrogenase 1 (ALDH1) expression, and decrease mammosphere and progenitor colony formation. Furthermore, we characterized exosomal trafficking of microRNAs in DCIS and found that several microRNAs (miRs) including miR-140, miR-29a, and miR-21 are differentially expressed in exosomes from DCIS stem-like cells. We found that SFN treatment could reprogram DCIS stem-like cells as evidenced by significant changes in exosomal secretion more closely resembling that of non-stem cancer cells. Finally, we demonstrated that exosomal secretion of miR-140 might impact signaling in nearby breast cancer cells.

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