Postinfectious and Immunological Disorders

1987 ◽  
pp. 131-139
Author(s):  
Gerald S. Golden
Keyword(s):  
Immunological Disorders

Characteristics of innate lymphoid cells (ILCs) and their role in immunological disorders (an update)

2015 ◽  
Vol 298 (1-2) ◽  
pp. 66-76 ◽  
Author(s):  
Reza Yazdani ◽  
Mehri Sharifi ◽  
Aylar Saba Shirvan ◽  
Gholamreza Azizi ◽  
Mazdak Ganjalikhani-Hakemi
Keyword(s):  
Innate Lymphoid Cells ◽  
Lymphoid Cells ◽  
Immunological Disorders

Liver transplanted patients with preoperative autoimmune hepatitis and immunological disorders are at increased risk for Post-Transplant Lymphoproliferative Disease (PTLD)

2010 ◽  
Vol 21 (3) ◽  
pp. 208-215 ◽  
Author(s):  
Tim Zimmermann ◽  
Maria Hoppe-Lotichius ◽  
Vuk Tripkovic ◽  
Ana P. Barreiros ◽  
Thomas C. Wehler ◽  
...  
Keyword(s):  
Autoimmune Hepatitis ◽  
Lymphoproliferative Disease ◽  
Post Transplant ◽  
Immunological Disorders ◽  
Increased Risk

scholarly journals Understanding dendritic cell biology and its role in immunological disorders through proteomic profiling

2009 ◽  
Vol 4 (2) ◽  
pp. 190-203 ◽  
Author(s):  
Gabriela Bomfim Ferreira ◽  
Chantal Mathieu ◽  
Lut Overbergh
Keyword(s):  
Dendritic Cell ◽  
Cell Biology ◽  
Proteomic Profiling ◽  
Immunological Disorders

IMMUNOLOGICAL DISORDERS OF THE REPRODUCTIVE SYSTEM THAT OCCUR WHEN EXPOSED TO BENZENE, IN EMPLOYEES OF OIL-PRODUCING ENTERPRISES

2021 ◽  
Author(s):  
I.V. Leshkova ◽  
◽  
O.V. Dolgih ◽  
O.YU. Ustinova
Keyword(s):  
Cell Death ◽  
Reproductive Health ◽  
Reproductive System ◽  
Death Receptor ◽  
Annexin V ◽  
Reference Level ◽  
Immunological Disorders ◽  
Cellular Expression ◽  
Cell Death Receptor

Abstract. Introduction. The protection of the reproductive health of the working-age population is the most important direction of State policy. In 5-15% of cases, the causes of reproductive dysfunction are immunological disorders. Benzene belongs to the group of industrial reprotoxicants, however, its effect of benzene on the reproductive system has not been sufficiently studied. Objective: to study the immunological aspects of the effect of benzene on the reproductive system. Methods. We examined 50 men exposed to benzene with reproductive disorders (26-49 years old), as well as 4 workers with normal sexual function aged 53-60 years. Spontaneous and induced changes in the cellular expression of apoptosis markers were studied. For the study, the ANNEXIN V-FITC/7-AAD kit was used for the detection of cells that have undergone apoptosis. The experiment was conducted in vitro using a biological medium (ejaculate). A factor of the chemical nature was benzene. Results. According to the results of the comparative analysis, there were no significant deviations of pathogenetic tests of immunological markers in comparison with the reference level in the spontaneous expression samples, but there was an excess of expression of the CD95 + cell death receptor (p<0.05) in 30% of the samples examined, and a decrease in the number of Annexin V-FITC+7AAD negative cells (without reaching the significance level) in samples with a load of (15%). There was a difference in the expression levels of CD95+ and CD25+ CD-reception indicators by 20% and 10% in relation to the spontaneous level (p<0.05). Representatives of the chemical group of aromatic hydrocarbons realize reprotoxicity, using the mechanism of excessive induction of the membrane signaling of the cell death receptor, accelerate the natural program of cell death by approximately 20% compared to the state of reproductive cells that were not stimulated. Conclusion. At the present stage, one of the tasks of occupational medicine is to study the effect of chemicals on the processes of reproduction, to develop new approaches to assessing the risk of their impact on the reproductive health of workers.

Motor neurone disease associated with several immunological disorders: A case report

1994 ◽  
Vol 124 ◽  
pp. 70-71 ◽  
Author(s):  
Marija Sostarko ◽  
Zdravko Brzovic ◽  
Davorka Vranjes
Keyword(s):  
Case Report ◽  
Motor Neurone ◽  
Motor Neurone Disease ◽  
Immunological Disorders

scholarly journals A SILICOSIS WITH IMMUNOLOGICAL DISORDERS SIMILAR TO SYSTEMIC LUPUS ERYTHEMATODES

1973 ◽  
Vol 62 (6) ◽  
pp. 620-625 ◽  
Author(s):  
Akira OHASHI ◽  
Yoshinori IRIUDA ◽  
Hirotsugu NAKA ◽  
Kazunori YAMADA ◽  
Hideki KAWAUHI ◽  
...  
Keyword(s):  
Lupus Erythematodes ◽  
Systemic Lupus ◽  
Immunological Disorders ◽  
Systemic Lupus Erythematodes

scholarly journals Epigenetic Regulations of Inflammatory Cyclooxygenase-Derived Prostanoids: Molecular Basis and Pathophysiological Consequences

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Hedi Harizi
Keyword(s):  
Target Genes ◽  
Inflammatory Diseases ◽  
Epigenetic Alterations ◽  
Therapeutic Approaches ◽  
Immunological Disorders ◽  
Tissue Microenvironment ◽  
Individual Variations ◽  
Fine Regulation ◽  
Additional Level ◽  
The Impact

The potential relevance of prostanoid signaling in immunity and immunological disorders, or disease susceptibility and individual variations in drug responses, is an important area for investigation. The deregulation of Cyclooxygenase- (COX-) derived prostanoids has been reported in several immunoinflammatory disorders such as asthma, rheumatoid arthritis, cancer, and autoimmune diseases. In addition to the environmental factors and the genetic background to diseases, epigenetic mechanisms involved in the fine regulation of prostanoid biosynthesis and/or receptor signaling appeared to be an additional level of complexity in the understanding of prostanoid biology and crucial in controlling the different components of the COX pathways. Epigenetic alterations targeting inflammatory components of prostanoid biosynthesis and signaling pathways may be important in the process of neoplasia, depending on the tissue microenvironment and target genes. Here, we focused on the epigenetic modifications of inflammatory prostanoids in physiological immune response and immunological disorders. We described how major prostanoids and their receptors can be functionally regulated epigenetically and consequently the impact of these processes in the pathogenesis inflammatory diseases and the development of therapeutic approaches that may have important clinical applications.

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