The Economics of Near Patient Testing

1988 ◽  
pp. 17-23 ◽  
Author(s):  
Vincent Marks
Keyword(s):  
Near Patient Testing

Determination of the International Sensitivity Index of a New Near-Patient Testing Device to Monitor Oral Anticoagulant Therapy

1997 ◽  
Vol 78 (02) ◽  
pp. 855-858 ◽  
Author(s):  
Armando Tripodi ◽  
Veena Chantarangkul ◽  
Marigrazia Clerici ◽  
Barbara Negri ◽  
Pier Mannuccio Mannucci
Keyword(s):  
Linear Relationship ◽  
Whole Blood ◽  
Oral Anticoagulant ◽  
Oral Anticoagulant Therapy ◽  
Oral Anticoagulants ◽  
Calibration Model ◽  
Testing Device ◽  
Data Points ◽  
Near Patient Testing

SummaryA key issue for the reliable use of new devices for the laboratory control of oral anticoagulant therapy with the INR is their conformity to the calibration model. In the past, their adequacy has mostly been assessed empirically without reference to the calibration model and the use of International Reference Preparations (IRP) for thromboplastin. In this study we reviewed the requirements to be fulfilled and applied them to the calibration of a new near-patient testing device (TAS, Cardiovascular Diagnostics) which uses thromboplastin-containing test cards for determination of the INR. On each of 10 working days citrat- ed whole blood and plasma samples were obtained from 2 healthy subjects and 6 patients on oral anticoagulants. PT testing on whole blood and plasma was done with the TAS and parallel testing for plasma by the manual technique with the IRP CRM 149S. Conformity to the calibration model was judged satisfactory if the following requirements were met: (i) there was a linear relationship between paired log-PTs (TAS vs CRM 149S); (ii) the regression line drawn through patients data points, passed through those of normals; (iii) the precision of the calibration expressed as the CV of the slope was <3%. A good linear relationship was observed for calibration plots for plasma and whole blood (r = 0.98). Regression lines drawn through patients data points, passed through those of normals. The CVs of the slope were in both cases 2.2% and the ISIs were 0.965 and 1.000 for whole blood and plasma. In conclusion, our study shows that near-patient testing devices can be considered reliable tools to measure INR in patients on oral anticoagulants and provides guidelines for their evaluation.

scholarly journals Antibiotics and near-patient testing: Differences in habits between physicians completing or discontinuing a medical audit

Health ◽  
2014 ◽  
Vol 06 (02) ◽  
pp. 141-148 ◽  
Author(s):  
Katarina Hedin ◽  
Annika Brorsson ◽  
Sigvard Mölstad ◽  
Eva Lena Strandberg
Keyword(s):  
Medical Audit ◽  
Near Patient Testing

Hydroxybutyrate near-patient testing to evaluate a new end-point for intravenous insulin therapy in the treatment of diabetic ketoacidosis in children

2007 ◽  
Vol 8 (3) ◽  
pp. 150-156 ◽  
Author(s):  
Kathryn J Noyes ◽  
Patricia Crofton ◽  
Louise E Bath ◽  
Angela Holmes ◽  
Lesley Stark ◽  
...  
Keyword(s):  
Insulin Therapy ◽  
Diabetic Ketoacidosis ◽  
End Point ◽  
Intravenous Insulin ◽  
Near Patient Testing

Near-patient testing, infection biomarkers, and rapid diagnostics

2016 ◽  
Author(s):  
Matthew Dryden
Keyword(s):  
Targeted Therapy ◽  
Molecular Diagnostics ◽  
Gold Standard ◽  
Standard Of Care ◽  
Clinical Judgement ◽  
Rapid Diagnostics ◽  
Microbiology Laboratory ◽  
Target Therapies ◽  
Laboratory Results ◽  
Near Patient Testing

Treating patients with targeted antimicrobial therapy is the gold standard of care. However, empiric antimicrobial guidelines are in operation for many patients in primary or secondary care with infection. These guidelines are based on previous surveillance data and/or national recommendations, but the decision to start treatment and the choice of antimicrobial is a best-guess approach, based on clinical judgement. Microbiology laboratory results help guide and target therapies, but in general they take about 1 to 2 days to be available due to the processes involved in culturing organisms. Improvement in speed of diagnosis is the focus of research, particularly around molecular diagnostics. Near-patient testing and the use of biomarkers has been discussed as a way to tackle this issue. This chapter also considers the alternatives and future strategies that could be deployed to improve the targeted therapy of antimicrobials.

Patientennahe Diagnostik in Krisensituationen / Near patient testing in exceptional situations

2006 ◽  
Vol 30 (4) ◽  
pp. 211-218 ◽  
Author(s):  
Steffen Friedewald ◽  
Ernst-Jürgen Finke ◽  
Gerhard Dobler
Keyword(s):  
Near Patient Testing
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