Production of Growth Factors by Normal Human Mammary Cells in Culture

1987 ◽  
pp. 227-239 ◽  
Author(s):  
William R. Kidwell ◽  
David S. Salomon ◽  
S. Mohanam ◽  
Graeme I. Bell
Keyword(s):  
Growth Factors ◽  
Mammary Cells ◽  
Cells In Culture ◽  
Normal Human

Brief Communication: Normal Human Mammary Cells in Culture: Evidence for OncornavirusMLike Particles2

1974 ◽  
Vol 52 (3) ◽  
pp. 975-981 ◽  
Author(s):  
P. Furmanski ◽  
C. Longley ◽  
D. Fouchey ◽  
R. Rich ◽  
M. A. Rich
Keyword(s):  
Mammary Cells ◽  
Cells In Culture ◽  
Normal Human

Growth of normal human mammary cells in culture

In Vitro ◽  
1980 ◽  
Vol 16 (5) ◽  
pp. 415-425 ◽  
Author(s):  
M. Stampfer ◽  
R. C. Hallowes ◽  
A. J. Hackett
Keyword(s):  
Mammary Cells ◽  
Cells In Culture ◽  
Normal Human

scholarly journals Studies on Insulin-like Growth Factors (IGF-I, -II) and There Binding Proteins in Normal Human Pregnancy

1990 ◽  
Vol 66 (7) ◽  
pp. 688-699 ◽  
Author(s):  
Toru FUNAKOSHI ◽  
Yasuo UEDA ◽  
Akio KOBAYASHI ◽  
Hajime MORIKAWA ◽  
Mastuto MOCHIZUKI
Keyword(s):  
Growth Factors ◽  
Binding Proteins ◽  
Human Pregnancy ◽  
Igf I ◽  
Normal Human ◽  
Insulin Like Growth Factors

Oscillating activity of a calcium-activated K+ channel in normal and cancerous mammary cells in culture

1991 ◽  
Vol 119 (2) ◽  
pp. 133-139 ◽  
Author(s):  
Koh-Ichi Enomoto ◽  
Kishio Furuya ◽  
Takashi Maeno ◽  
Charles Edwards ◽  
Takami Oka
Keyword(s):  
K Channel ◽  
Mammary Cells ◽  
Cells In Culture

The Influence of Steroid Hormones and Antihormones on the Growth and Differentiation of Normal Human Breast Cells in Culture

1992 ◽  
pp. 145-156 ◽  
Author(s):  
Frederique Kuttenn ◽  
Anne Gompel ◽  
Catherine Malet ◽  
Etienne Leygue ◽  
Nicole Baudot ◽  
...  
Keyword(s):  
Steroid Hormones ◽  
Human Breast ◽  
Cells In Culture ◽  
Normal Human Breast ◽  
Breast Cells ◽  
Normal Human

Effects of oestrogen on human breast cancer cells in culture

1989 ◽  
Vol 95 ◽  
pp. 119-132 ◽  
Author(s):  
Philippa D. Darbre ◽  
Roger J. Daly
Keyword(s):  
Breast Cancer ◽  
Growth Factors ◽  
Cell Lines ◽  
Human Breast Cancer ◽  
Breast Cancer Cell Lines ◽  
Phenol Red ◽  
Human Breast ◽  
Cells In Culture ◽  
D Cells

SynopsisOestrogen regulates the growth of human breast cancer cell lines ZR-75–1, T-47-D and MCF-7 (KO and McGrath). Basal cell growth can be reduced (T-47-D) or eliminated (ZR-75–1) by prior growth in the absence of steroid and phenol red for three weeks, demonstrating that oestrogens can have long-lasting effects on cells in culture (termed “steroid memory”). Effects of oestradiol on different cell biological parameters are described and interaction with other steroids and serum growth factors is discussed. Antioestrogen action in these cell lines is affected by at least five parameters: (1) presence of phenol red, (2) time in culture, (3) cell density, (4) antioestrogen concentration, (5) steroid memory.An in vitro model for loss of oestrogen sensitivity in breast cancer is presented. Both dependent (ZR-75–1) and responsive (T-47-D) cells lose oestrogen sensitivity when deprived of steroid in the long term but show a gradual increase in growth. For ZR-75–1 cells, the effects appear to be clonal but occur at a high frequency (about 1 in 1,000 cells). Parallel alterations in sensitivity to other steroids, antioestrogens and serum growth factors are shown. Molecular markers of this action are described and the results compared with the well-established model for loss of androgen/glucocorticoid sensitivity in SI 15 cells.

Secretion of Polypeptide Growth Factors by Human Nonfunctioning Pituitary Adenoma Cells in Culture

1993 ◽  
Vol 57 (5) ◽  
pp. 825-834 ◽  
Author(s):  
Ulrich Renner ◽  
Juri Mojto ◽  
Eduardo Arzt ◽  
Manfred Lange ◽  
Johanna Stalla ◽  
...  
Keyword(s):  
Growth Factors ◽  
Pituitary Adenoma ◽  
Nonfunctioning Pituitary Adenoma ◽  
Cells In Culture ◽  
Polypeptide Growth Factors
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