Analysis of Anesthesia Effect of Dexmedetomidine in Clinical Operation of Replantation of Severed Finger

Brachial plexus block commonly used in finger replantation has the advantages of simple operation, small side effects, and stable circulation, but it has inherent problems such as imperfect block range, slow onset of anesthesia, and short maintenance time of anesthesia. In order to explore the reliable clinical anesthesia effect, this paper uses experimental investigation methods to study the effect of dexmedetomidine in clinical surgery of replantation of severed fingers. Moreover, this paper uses comparative test methods, uses statistical methods to process test data, and uses intuitive methods to display test results. Finally, this paper verifies the reliability of dexmedetomidine in replantation of severed finger through comparative analysis and verifies that the anesthesia method proposed in this paper has certain user satisfaction through parameter survey.

Multidimensional Food Security Nexus in Drylands under the Slow Onset Effects of Climate Change

Hyperarid, arid, semiarid, and dry subhumid areas cover approximately 41% of the global land area. The human population in drylands, currently estimated at 2.7 billion, faces limited access to sufficient, affordable, and nutritious food. We discuss the interlinkages among water security, environmental security, energy security, economic security, health security, and food security governance, and how they affect food security in drylands. Reliable and adequate water supply, and the prevention of water contamination, increase the potential for ample food, fodder, and fiber production. Protecting woodlands and rangelands increases food security by buffering the slow onset effects of climate change, including biodiversity loss, desertification, salinization, and land degradation. The protection of natural lands is expected to decrease environmental contamination, and simultaneously, reduce the transfer of diseases from wildlife to humans. Biofuel production and hydroelectric power plants increase energy security but generate land-use conflicts, deforestation, and ecosystem degradation. Economic security generally positively correlates with food security. However, economic growth often degrades the environment, changes tenure rights over natural resources, and stimulates migration to urban areas, resulting in lower food and health security. Moreover, civil unrest, political instability, and armed conflicts disrupt local economies in drylands. Maintaining food security is crucial for health security; conversely, malnourished populations and unresponsive health systems decrease economic security, and adversely affect environmental, energy, and food security. Climate change is expected to deteriorate health security by spreading vector-borne diseases. Effective governance and timely interventions can substantially shorten periods of food insecurity, lower their intensities, and accelerate recovery from inevitable crises, and are therefore crucial in preventing humanitarian crises. Since global drylands population will nearly double by 2050, and since drylands are among the most susceptible areas to climate change, integrated multi-hazard approaches to food security are needed.

Emerging Role of Flavonoids as the Treatment of Depression

Depression is one of the most frequently observed psychological disorders, affecting thoughts, feelings, behavior and a sense of well-being in person. As per the WHO, it is projected to be the primitive cause of various other diseases by 2030. Clinically, depression is treated by various types of synthetic medicines that have several limitations such as side-effects, slow-onset action, poor remission and response rates due to complicated pathophysiology involved with depression. Further, clinically, patients cannot be given the treatment unless it affects adversely the job or family. In addition, synthetic drugs are usually single targeted drugs. Unlike synthetic medicaments, there are many plants that have flavonoids and producing action on multiple molecular targets and exhibit anti-depressant action by affecting multiple neuronal transmissions or pathways such as noradrenergic, serotonergic, GABAnergic and dopaminergic; inhibition of monoamine oxidase and tropomyosin receptor kinase B; simultaneous increase in nerve growth and brain-derived neurotrophic factors. Such herbal drugs with flavonoids are likely to be useful in patients with sub-clinical depression. This review is an attempt to analyze pre-clinical studies, structural activity relationship and characteristics of reported isolated flavonoids, which may be considered for clinical trials for the development of therapeutically useful antidepressant.

Land Value in a Disaster-Prone Urbanized Coastal Area: A Case Study from Semarang City, Indonesia

Coastal areas have been growing massively worldwide. The fast growth also affects the land value in either a positive or a negative way. Many scholars have studied land value and the factors that affect it in areas prone to sudden-onset disasters. In contrast, studies on urbanized coastal areas that suffer from slow-onset disasters are still lacking. Using a case study from Semarang City in Indonesia, this research aims at ameliorating this limitation. To comprehensively understand the aim, two research questions are addressed: (1) What is the distribution of land value in urbanized coastal areas? (2) How do the different distribution factors determine the land value? Based on in-depth interviews with key persons, map analyses, and desk studies, this research discovers that land value is distributed randomly among coastal areas. The dynamics of land value are determined by road access, distance, and accessibility to the city center and CBD, public facilities, transportation facilities, population composition, physical environment, and disasters. Surprisingly, the coastal areas in Semarang that experience combined disasters showed that disasters could not decrease the land value; the value in some areas is constant or even increasing. This shows the different impacts of disasters on land value for slow-onset disasters and sudden-onset disasters.

Toward a Typology of Displacements in the Context of Slow-Onset Environmental Degradation. An Analysis of Hazards, Policies, and Mobility Patterns

The aim of this paper is to develop a typology of displacement in the context of slow-onset environmental degradation linked to climate change (desertification, droughts and increasing temperatures, sea level rise (SLR), loss of biodiversity, land/forest degradation, and glacial retreat). We differentiate regions under environmental threat according to their social vulnerabilities, mobility patterns, and related policies, and identify twelve types of vulnerability/policy/mobility combinations. The paper is based on a synthesis of 321 published case studies on displacement and slow-onset environmental degradation, representing a comprehensive collection of the literature since the 1970s. We observe that vulnerability is especially critical in small island and coastal contexts, as well as in mountainous zones and desert regions. Migration processes are often not visible in areas affected by environmental degradation. When they do occur, they remain mostly internal and oriented towards cities with occasional rural-to-rural migration. Non-mobile people, as well as those who depend on natural resource industries for their livelihoods, are particularly vulnerable to climate change. Persons with lower levels of education are more likely to respond to environmental shock through short-distance migration, whereas highly educated individuals may migrate over longer distances. Policies that directly address mobility in relation to climate change—mostly through relocation—are seldom mentioned in the literature. Mobility is often perceived as a last-resort solution, whereas a growing body of research identifies mobility as an adaptation strategy.

Case of Severe Treatment-Resistant Cryptogenic Organizing Pneumonia

Cryptogenic organizing pneumonia is a rare interstitial lung disease with different onset of symptoms, which responds rapidly to glucocorticoid treatment. We present a case of cryptogenic organizing pneumonia which manifested as a progressive 3-year dyspnea that ultimately has led to acute respiratory failure. Moreover, treatment with prednisone for this patient exhibited slow onset of the effect.

Climate-Induced Relocation and Social Change in Keta, Ghana

In this article, I analyze the resettlement of three communities in the Keta municipality of Ghana as a result of rising sea levels that threatened life and property. Although a few studies have documented the effects of relocation because of slow-onset climate-induced environmental change, little is known about how such resettlements have contributed to positive social change in the affected communities. I used critical theory to determine whether Keta’s relocation process contributed to positive social change. Transcriptions of interviews with a purposeful sample of 35 household members were coded and categorized into themes for essence description. Improved educational infrastructure for personal development, improved housing facilities, saved lives and protected culture, and improved healthcare facilities and general well-being were among the positive outcomes. Hence, through this study, I provide evidence to consider the need to prioritize the positive social change such resettlements will make in the lives of the affected populations in climate-induced resettlement and adaptation in Ghana and other parts of the world. <em>Keywords</em>: Climate change, relocation, resettlement, social change, sea level rise, improved livelihoods