P2-027: TARGET ENGAGEMENT IN A PHASE II CLINICAL TRIAL OF AAV2-NGF GENE THERAPY FOR ALZHEIMER'S DISEASE

2006 ◽  
Vol 14 (7S_Part_12) ◽  
pp. P677-P677
Author(s):  
Michael J. Castle ◽  
Fernando Calvo Baltanas ◽  
Imre Kovacs ◽  
Alan H. Nagahara ◽  
Krystof S. Bankiewicz ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Trial ◽  
Gene Therapy ◽  
Phase Ii ◽  
Phase Ii Clinical Trial ◽  
Target Engagement ◽  
Ngf Gene

scholarly journals Postmortem Analysis in a Clinical Trial of AAV2-NGF Gene Therapy for Alzheimer's Disease Identifies a Need for Improved Vector Delivery

2020 ◽  
Vol 31 (7-8) ◽  
pp. 415-422 ◽  
Author(s):  
Michael J. Castle ◽  
Fernando C. Baltanás ◽  
Imre Kovacs ◽  
Alan H. Nagahara ◽  
David Barba ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Trial ◽  
Gene Therapy ◽  
Vector Delivery ◽  
Ngf Gene

Donepezil Improves Gait Performance in Older Adults with Mild Alzheimer's Disease: A Phase II Clinical Trial

2014 ◽  
Vol 43 (1) ◽  
pp. 193-199 ◽  
Author(s):  
Manuel Montero-Odasso ◽  
Susan W. Muir-Hunter ◽  
Afua Oteng-Amoako ◽  
Karen Gopaul ◽  
Anam Islam ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Clinical Trial ◽  
Phase Ii ◽  
Phase Ii Clinical Trial ◽  
Gait Performance

scholarly journals O4-06-05: PF-04447943: A phase II controlled clinical trial of a selective PDE9A inhbitor in Alzheimer's disease

2011 ◽  
Vol 7 ◽  
pp. S695-S695 ◽  
Author(s):  
Elias Schwam ◽  
Rebecca Evans ◽  
Timothy Nicholas ◽  
Robert Chew ◽  
Wendy Davidson ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Trial ◽  
Phase Ii ◽  
Controlled Clinical Trial

P3-037: CLINICAL TRIAL DESIGN FOR A PHASE II, RANDOMIZED, PLACEBO-CONTROLLED TRIAL OF AMX0035 IN ALZHEIMER'S DISEASE

2006 ◽  
Vol 14 (7S_Part_20) ◽  
pp. P1078-P1079
Author(s):  
Kent L. Leslie ◽  
Joshua Cohen ◽  
Justin Klee ◽  
Victoria Williams ◽  
Steven E. Arnold
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Trial ◽  
Phase Ii ◽  
Trial Design ◽  
Controlled Trial ◽  
Clinical Trial Design

Analyses of a Phase 1 Clinical Trial of Adeno- associated Virus-Nerve Growth Factor (CERE-110) Gene Therapy in Alzheimer's Disease

Neurosurgery ◽  
2007 ◽  
Vol 61 (1) ◽  
pp. 216-216 ◽  
Author(s):  
Roy A.E. Bakay ◽  
Zoe Arvanitakis ◽  
Mark Tuszynski ◽  
Steve Potkin ◽  
Ray Bartus ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Trial ◽  
Gene Therapy ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Phase 1 ◽  
Adeno Associated Virus ◽  
Nerve Growth ◽  
Phase 1 Clinical Trial
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