Facile Synthetic Access to Glycopeptide Antibiotic Precursor Peptides for the Investigation of Cytochrome P450 Action in Glycopeptide Antibiotic Biosynthesis

2016 ◽  
pp. 85-102 ◽  
Author(s):  
Clara Brieke ◽  
Veronika Kratzig ◽  
Madeleine Peschke ◽  
Max J. Cryle
Keyword(s):  
Cytochrome P450 ◽  
Antibiotic Biosynthesis ◽  
Glycopeptide Antibiotic

More than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH

2016 ◽  
Vol 12 (10) ◽  
pp. 2992-3004 ◽  
Author(s):  
Veronika Ulrich ◽  
Madeleine Peschke ◽  
Clara Brieke ◽  
Max J. Cryle
Keyword(s):  
Cytochrome P450 ◽  
Coupling Reaction ◽  
Glycopeptide Antibiotic

Cytochrome P450 StaH catalyses the first cyclisation reaction in the biosynthesis of the glycopeptide antibiotic A47934 via recruitment to the NRPS machinery through interaction with the X-domain.

scholarly journals Halogenation of glycopeptide antibiotics occurs at the amino acid level during non-ribosomal peptide synthesis

2017 ◽  
Vol 8 (9) ◽  
pp. 5992-6004 ◽  
Author(s):  
Tiia Kittilä ◽  
Claudia Kittel ◽  
Julien Tailhades ◽  
Diane Butz ◽  
Melanie Schoppet ◽  
...  
Keyword(s):  
Amino Acid ◽  
Peptide Synthesis ◽  
Acid Level ◽  
Amino Acid Level ◽  
Antibiotic Biosynthesis ◽  
Carrier Protein ◽  
Glycopeptide Antibiotics ◽  
Glycopeptide Antibiotic ◽  
Protein Substrates

Halogenase enzymes involved in glycopeptide antibiotic biosynthesis accept aminoacyl-carrier protein substrates.

Comparative analysis and insights into the evolution of gene clusters for glycopeptide antibiotic biosynthesis

2005 ◽  
Vol 274 (1) ◽  
pp. 40-50 ◽  
Author(s):  
Stefano Donadio ◽  
Margherita Sosio ◽  
Evi Stegmann ◽  
Tilmann Weber ◽  
Wolfgang Wohlleben
Keyword(s):  
Comparative Analysis ◽  
Gene Clusters ◽  
Antibiotic Biosynthesis ◽  
Glycopeptide Antibiotic

scholarly journals The Diiron Monooxygenase CmlA from Chloramphenicol Biosynthesis Allows Reconstitution of β-Hydroxylation during Glycopeptide Antibiotic Biosynthesis

2019 ◽  
Vol 14 (12) ◽  
pp. 2932-2941 ◽  
Author(s):  
Milda Kaniusaite ◽  
Robert J. A. Goode ◽  
Ralf B. Schittenhelm ◽  
Thomas M. Makris ◽  
Max J. Cryle
Keyword(s):  
Antibiotic Biosynthesis ◽  
Glycopeptide Antibiotic

scholarly journals The Thioesterase Domain in Glycopeptide Antibiotic Biosynthesis Is Selective for Cross-Linked Aglycones

2017 ◽  
Vol 13 (1) ◽  
pp. 110-120 ◽  
Author(s):  
Madeleine Peschke ◽  
Clara Brieke ◽  
Michael Heimes ◽  
Max J. Cryle
Keyword(s):  
Antibiotic Biosynthesis ◽  
Glycopeptide Antibiotic
Sign in / Sign up

Export Citation Format

Share Document