Micellar Polymer Encapsulation of Enzymes

2016 ◽  
pp. 93-108 ◽  
Author(s):  
Sabina Besic ◽  
Shelley D. Minteer
Keyword(s):  
Polymer Encapsulation

scholarly journals Sustained-Release Hydromorphone Microparticles Produced by Supercritical Fluid Polymer Encapsulation

2019 ◽  
Vol 108 (2) ◽  
pp. 811-814 ◽  
Author(s):  
Felicity Y. Han ◽  
Andrew Whittaker ◽  
Steven M. Howdle ◽  
Andrew Naylor ◽  
Anjumn Shabir-Ahmed ◽  
...  
Keyword(s):  
Sustained Release ◽  
Supercritical Fluid ◽  
Polymer Encapsulation

scholarly journals Grafting of Encapsulated Dopamine-Secreting Cells in Parkinson's Disease: Long-Term Primate Study

2000 ◽  
Vol 9 (5) ◽  
pp. 705-709 ◽  
Author(s):  
Isao Date ◽  
Tetsuro Shingo ◽  
Hideyuki Yoshida ◽  
Kenjiro Fujiwara ◽  
Kazuki Kobayashi ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Pc12 Cells ◽  
Tumor Formation ◽  
Functional Improvement ◽  
Functional Changes ◽  
Polymer Encapsulation ◽  
Encapsulated Cells ◽  
Fluid Analysis

The transplantation of encapsulated dopamine-secreting cells into the striatum represents one potential means of treating Parkinson's disease. The present study investigated the ability of encapsulated PC12 cells, which are derived from rat pheochromocytoma, to supply L-dopa and dopamine into the primate brain in the long term and to effect functional improvement in the animals. Following polymer encapsulation, PC12 cells were transplanted into the striatum of hemiparkinsonian monkeys. The secretion of L-dopa and dopamine from the encapsulated cells, the morphology of these cells, the histology of the host striatum surrounding the capsule, and functional changes in the host animals were examined 1, 6, and 12 months after transplantation. Analysis of retrieved capsules revealed that the PC12 cells survived and continued to release L-dopa and dopamine even 12 months after transplantation. The histological response of the host brain surrounding the capsules was minimal and there were no signs of immunological rejection or tumor formation. The physical condition of the host animals was good for 12 months, and hematologic and cerebrospinal fluid analysis revealed that no animals suffered from infection or immunological reaction. These PC12 cell-grafted monkeys showed improvements in hand movements after transplantation, effects that lasted for at least 12 months. These results further support the potential use of this approach for the treatment of Parkinson's disease.

Polymer encapsulation effects on the magnetism of EuS nanocrystals

2008 ◽  
Vol 18 (38) ◽  
pp. 4572 ◽  
Author(s):  
Angela Sofia Pereira ◽  
Protima Rauwel ◽  
Mário Souza Reis ◽  
Nuno João Oliveira Silva ◽  
Ana Barros-Timmons ◽  
...  
Keyword(s):  
Polymer Encapsulation

scholarly journals Polymer-encapsulation of iron oxide clusters using macroRAFT block copolymers as stabilizers: tuning of the particle morphology and surface functionalization

2020 ◽  
Vol 8 (22) ◽  
pp. 4917-4929 ◽  
Author(s):  
Thiago Rodrigues Guimarães ◽  
Muriel Lansalot ◽  
Elodie Bourgeat-Lami
Keyword(s):  
Iron Oxide ◽  
Block Copolymers ◽  
Surface Functionalization ◽  
Particle Morphology ◽  
Amphiphilic Block Copolymers ◽  
Oxide Content ◽  
Iron Oxide Content ◽  
Polymer Encapsulation ◽  
Magnetic Carriers ◽  
Surface Functionalizations

We report a versatile platform for the preparation of magnetic carriers stabilized by macroRAFT amphiphilic block copolymers, exhibiting encapsulated morphologies, high iron oxide content and tailored surface functionalizations.

Radical initiator modified cerium oxide nanoparticles for polymer encapsulation via grafting from the surface

RSC Advances ◽  
2014 ◽  
Vol 4 (106) ◽  
pp. 61863-61868 ◽  
Author(s):  
Eric Johansson Salazar-Sandoval ◽  
Miren Aguirre ◽  
María Paulis ◽  
José R. Leiza ◽  
Mats Johansson ◽  
...  
Keyword(s):  
Cerium Oxide ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Ceria Nanoparticles ◽  
Polymer Encapsulation ◽  
Radical Initiator ◽  
Grafting From

The present paper describes a versatile route to modify and stabilize ceria nanoparticles with a radical initiator, 4,4′-azobis(4-cyanovaleric acid) (ACVA), allowing a strong interface to be formed via grafting of polymers from the surface.

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