Hepatic Encephalopathy and Alterations of Cerebral Function

2010 ◽  
pp. 171-187
Author(s):  
Juan Córdoba ◽  
Rita García-Martinez
Keyword(s):  
Hepatic Encephalopathy ◽  
Cerebral Function

Hepatic Encephalopathy Diagnostic Test Effective

2010 ◽  
Vol 40 (10) ◽  
pp. 42-43
Author(s):  
BRUCE JANCIN
Keyword(s):  
Hepatic Encephalopathy ◽  
Diagnostic Test

Hepatic Encephalopathy Can Impair Driving

2008 ◽  
Vol 38 (19) ◽  
pp. 28
Author(s):  
DAMIAN MCNAMARA
Keyword(s):  
Hepatic Encephalopathy

Effects of SNPs in HE-relevant genes on the development of hepatic encephalopathy in patients with liver cirrhosis

2019 ◽  
Author(s):  
MS Jördens ◽  
V Keitel ◽  
A Mertens ◽  
B Görg ◽  
D Häussinger
Keyword(s):  
Liver Cirrhosis ◽  
Hepatic Encephalopathy

Risk Factors for Hepatic Encephalopathy after Transjugular Intrahepatic Portosystemic Shunt in Patients with Hepatocellular Carcinoma and Portal Hypertension

2015 ◽  
Vol 24 (3) ◽  
pp. 301-307 ◽  
Author(s):  
Jiannan Yao ◽  
Li Zuo ◽  
Guangyu An ◽  
Zhendong Yue ◽  
Hongwei Zhao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatocellular Carcinoma ◽  
Portal Hypertension ◽  
Hepatic Encephalopathy ◽  
Pressure Gradient ◽  
Transjugular Intrahepatic Portosystemic Shunt ◽  
Meld Score ◽  
Portosystemic Shunt ◽  
Portal Flow ◽  
Intrahepatic Portosystemic Shunt

Aims: This study aimed at assessing the risk factors for hepatic encephalopathy (HE) after transjugular intrahepatic portosystemic shunt (TIPS) in patients with hepatocellular carcinoma (HCC) and portal hypertension. Method: Consecutive patients (n=279) with primary HCC who underwent TIPS between January 1997 and March 2012 at a single institution were retrospectively reviewed. Patients were followed up for 2 years. Pre-TIPS, peri-TIPS and post-TIPS clinical variables were reviewed using univariate and multivariate analyses to identify risk factors for HE after TIPS. Results: The overall incidence of HE was 41% (114/279). Multivariate analysis showed an increased odds for HE in patients with: >3 treatments with transcatheter arterial chemoembolization (TACE) and/or trans-arterial embolization (TAE) (odds ratio [OR], 4.078; 95% confidence interval [95%CI], 1.748-9.515); hepatopetal portal flow (OR, 2.362; 95%CI, 1.032-5.404); high portosystemic pressure gradient (OR, 1.198; 95%CI, 1.073-1.336) and high pre-TIPS MELD score (OR, 1.693; 95%CI, 1.390-2.062). Odds for HE were increased 1.693 fold for each 1-point increase in the MELD score, and 1.198 fold for each 1-mmHg decrease in the post-TIPS portosystemic pressure gradient. Conclusion: The identification of clinical variables associated with increased odds of HE may be useful for the selection of appropriate candidates for TIPS. Results suggest that an inappropriate decrease in the portosystemic pressure gradient might be associated with HE after TIPS. In addition, >3 treatments with TACE/TAE, hepatopetal portal flow, and high MELD score were also associated with increased odds of HE after TIPS. Key words:  –  –  – .

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