Chimeric Antigen Receptors for T-Cell Based Therapy

Author(s):  
Eleanor J. Cheadle ◽  
Vicky Sheard ◽  
Andreas A. Hombach ◽  
Markus Chmielewski ◽  
Tobias Riet ◽  
...  
Cancers ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1333
Author(s):  
Benjamin Motais ◽  
Sandra Charvátová ◽  
Matouš Hrdinka ◽  
Michal Šimíček ◽  
Tomáš Jelínek ◽  
...  

Hematological malignancies comprise over a hundred different types of cancers and account for around 6.5% of all cancers. Despite the significant improvements in diagnosis and treatment, many of those cancers remain incurable. In recent years, cancer cell-based therapy has become a promising approach to treat those incurable hematological malignancies with striking results in different clinical trials. The most investigated, and the one that has advanced the most, is the cell-based therapy with T lymphocytes modified with chimeric antigen receptors. Those promising initial results prepared the ground to explore other cell-based therapies to treat patients with blood cancer. In this review, we want to provide an overview of the different types of cell-based therapies in blood cancer, describing them according to the cell source.


2020 ◽  
Vol 11 (18) ◽  
pp. 5424-5431
Author(s):  
Ling-Lin Li ◽  
Hong-Ling Yuan ◽  
Yu-Qiong Yang ◽  
Lin Wang ◽  
Ren-Chao Zou

2020 ◽  
Author(s):  
Preeti Sharma ◽  
Venkata VVR Marada ◽  
Monika Kizerwetter ◽  
Claire P. Schane ◽  
Yanran He ◽  
...  

2020 ◽  
Vol 126 ◽  
pp. 56-64
Author(s):  
Han Xu ◽  
Agnes E. Hamburger ◽  
Jee-Young Mock ◽  
Xueyin Wang ◽  
Aaron D. Martin ◽  
...  

2020 ◽  
Vol 17 (6) ◽  
pp. 600-612 ◽  
Author(s):  
Ling Wu ◽  
Qianru Wei ◽  
Joanna Brzostek ◽  
Nicholas R. J. Gascoigne

2015 ◽  
Vol 23 ◽  
pp. S84
Author(s):  
Lingfeng Liu ◽  
Alexandra Cabanov ◽  
Paula Kosasih ◽  
Daniel Sommermeyer ◽  
Stanley R. Riddell

Leukemia ◽  
2017 ◽  
Vol 31 (10) ◽  
pp. 2191-2199 ◽  
Author(s):  
D Sommermeyer ◽  
T Hill ◽  
S M Shamah ◽  
A I Salter ◽  
Y Chen ◽  
...  

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