Aortocaval Fistula

2019 ◽  
pp. 341-347
Author(s):  
Kristine Clodfelter Orion ◽  
James H. Black
Keyword(s):  
Aortocaval Fistula

scholarly journals Fatal Case of a Contained Ruptured of the Infrarenal Aorta due to Simultaneous Primary Aortocaval Fistula and Aortoenteric Fistula

2021 ◽  
Author(s):  
Abdulhakim Ibrahim ◽  
Elena Marchiori ◽  
Alexander Oberhuber ◽  
Marco V. Usai
Keyword(s):  
Psoas Abscess ◽  
Aortic Rupture ◽  
Fatal Case ◽  
Aortoenteric Fistula ◽  
Infrarenal Aorta ◽  
Aortocaval Fistula ◽  
Antibiotic Management ◽  
Extensive Debridement ◽  
Crossover Bypass ◽  
Aortic Anastomosis

AbstractWe report an extremely rare case of primary aortocaval fistula with simultaneous development of an aortoenteric fistula in a 68-year-old man. The patient developed under oral anticoagulation a spontaneous intracaval aortic rupture. An emergency intervention was performed with a covering of the fistula with an aorto-uniiliac stent graft and a femoro-femoral crossover bypass. One week later, the patient was transferred to our institution with the diagnosis of a psoas abscess and a suspected concomitant aortoenteric fistula. We performed a complete explantation of the endograft and implanted it after extensive debridement an aortobiiliac bypass, made of bovine pericardium. The postoperative course was complicated, first by bleeding from the left iliac anastomosis, and then by bleeding from the proximal aortic anastomosis. The entire graft was explanted and an axillo-femoral bypass was implanted. The patient then developed a multi-organ failure and died 3 months later. If possible, an extended surgical debridement and resection of all infected tissue with in situ reconstruction is the gold standard. However, with this therapy, there is still a high risk of reinfection. Long-term antibiotic management is mandatory.

scholarly journals Decreased Substrate Stiffness Promotes a Hypofibrotic Phenotype in Cardiac Fibroblasts

2021 ◽  
Vol 22 (12) ◽  
pp. 6231
Author(s):  
Rachel C. Childers ◽  
Pamela A. Lucchesi ◽  
Keith J. Gooch
Keyword(s):  
Nuclear Translocation ◽  
Cardiac Fibroblasts ◽  
Volume Overload ◽  
Substrate Stiffness ◽  
Aortocaval Fistula ◽  
Failure Model ◽  
Tissue Stiffness ◽  
Mechanical Memory ◽  
Heart Failure Model ◽  
Control Sham

A hypofibrotic phenotype has been observed in cardiac fibroblasts (CFs) isolated from a volume overload heart failure model, aortocaval fistula (ACF). This paradoxical phenotype results in decreased ECM synthesis despite increased TGF-β presence. Since ACF results in decreased tissue stiffness relative to control (sham) hearts, this study investigates whether the effects of substrate stiffness could account for the observed hypofibrotic phenotype in CFs isolated from ACF. CFs isolated from ACF and sham hearts were plated on polyacrylamide gels of a range of stiffness (2 kPa to 50 kPa). Markers related to cytoskeletal and fibrotic proteins were measured. Aspects of the hypofibrotic phenotype observed in ACF CFs were recapitulated by sham CFs on soft substrates. For instance, sham CFs on the softest gels compared to ACF CFs on the stiffest gels results in similar CTGF (0.80 vs. 0.76) and transgelin (0.44 vs. 0.57) mRNA expression. The changes due to stiffness may be explained by the observed decreased nuclear translocation of transcriptional regulators, MRTF-A and YAP. ACF CFs appear to have a mechanical memory of a softer environment, supported by a hypofibrotic phenotype overall compared to sham with less YAP detected in the nucleus, and less CTGF and transgelin on all stiffnesses.

scholarly journals Bradykinin does not modulate the natriuretic response to atrial natriuretic factor in rats with aortocaval fistula.

Hypertension ◽  
1993 ◽  
Vol 21 (6_pt_2) ◽  
pp. 966-970 ◽  
Author(s):  
Z A Abassi ◽  
H Klein ◽  
J Cox ◽  
H R Keiser
Keyword(s):  
Atrial Natriuretic Factor ◽  
Aortocaval Fistula ◽  
Natriuretic Factor ◽  
Atrial Natriuretic

scholarly journals Congenital aortocaval fistula mimicking atrial septal defect on transthoracic echocardiography

2017 ◽  
Vol 1 ◽  
pp. 84-85
Author(s):  
Alaa Quisi ◽  
Gülhan Yüksel Kalkan ◽  
Ahmet Oytun Baykan ◽  
Murat Çaylı
Keyword(s):  
Atrial Septal Defect ◽  
Transthoracic Echocardiography ◽  
Septal Defect ◽  
Aortocaval Fistula

scholarly journals Evaluation of Atrial Natriuretic Peptide and Brain Natriuretic Peptide in Atrial Granules of Rats with Experimental Congestive Heart Failure

2001 ◽  
Vol 49 (10) ◽  
pp. 1293-1300 ◽  
Author(s):  
Gad M. Bialik ◽  
Zaid A. Abassi ◽  
Ilan Hammel ◽  
Joseph Winaver ◽  
Dina Lewinson
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Atrial Natriuretic Peptide ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Aortocaval Fistula ◽  
Granule Formation ◽  
Gold Particles ◽  
The Mean ◽  
Atrial Natriuretic

The natriuretic peptides are believed to play an important role in the pathophysiology of congestive heart failure (CHF). We utilized a quantitative cytomorphometric method, using double immunocytochemical labeling, to assess the characteristics of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in atrial granules in an experimental model of rats with CHF induced by aortocaval fistula. Rats with CHF were further divided into decompensated (sodium-retaining) and compensated (sodium-excreting) subgroups and compared with a sham-operated control group. A total of 947 granules in myocytes in the right atrium were analyzed, using electron microscopy and a computerized analysis system. Decompensated CHF was associated with alterations in the modal nature of granule content packing, as depicted by moving bin analysis, and in the granule density of both peptides. In control rats, the mean density of gold particles attached to both peptides was 347.0 ± 103.6 and 306.3 ± 89.9 gold particles/μm2 for ANP and BNP, respectively. Similar mean density was revealed in the compensated rats (390.6 ± 81.0 and 351.3 ± 62.1 gold particles/μm2 for ANP and BNP, respectively). However, in rats with decompensated CHF, a significant decrease in the mean density of gold particles was observed (141.6 ± 67.3 and 158.0 ± 71.2 gold particles/μm2 for ANP and BNP, respectively; p < 0.05 compared with compensated rats, for both ANP and BNP). The ANP:BNP ratio did not differ between groups. These findings indicate that the development of decompensated CHF in rats with aortocaval fistula is associated with a marked decrease in the density of both peptides in atrial granules, as well as in alterations in the quantal nature of granule formation. The data further suggest that both peptides, ANP and BNP, may be regulated in the atrium by a common secretory mechanism in CHF.

The distinct syndrome of spontaneous abdominal aortocaval fistula

1968 ◽  
Vol 44 (3) ◽  
pp. 464-473 ◽  
Author(s):  
H.Peter Nennhaus ◽  
Hushang Javid
Keyword(s):  
Aortocaval Fistula

scholarly journals Primary Aortocaval Fistula and Juxtarenal Aortic Aneurysm

2016 ◽  
Vol 51 (3) ◽  
pp. 357 ◽  
Author(s):  
Z. Szeberin ◽  
C. Csobay-Novák
Keyword(s):  
Aortic Aneurysm ◽  
Aortocaval Fistula

scholarly journals A rare case of paradoxical pulmonary embolism in spontaneous aortocaval fistula

2021 ◽  
pp. 20200183
Author(s):  
Valentina Vespro ◽  
Stefano Fusco ◽  
Anna Maria Ierardi ◽  
Viviana Grassi ◽  
Ilenia D’Alessio ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Inferior Vena ◽  
Rare Complication ◽  
Vena Cava ◽  
Paradoxical Embolism ◽  
Aortocaval Fistula ◽  
Shortness Of Breath ◽  
Right Heart ◽  
Abdominal Ct ◽  
Abdominal Aortic

Aortocaval fistula (ACF) is a rare complication of abdominal aortic aneurysm (AAA), occurring in less than 1% of all AAAs. Paradoxical embolism can rarely be associated with ACF, pulmonary embolism may originate from dislodgment of thrombotic material from the AAA in the inferior vena cava (IVC) through the ACF. We report a case of a patient admitted to the emergency department with abdominal pain and shortness of breath who immediately underwent thoraco-abdominal CT. Imaging allowed a prompt pre-operative diagnosis of an ACF between an AAA and the IVC, also identifying CT signs of right heart overload and the presence of a paradoxical pulmonary embolism.

Sign in / Sign up

Export Citation Format

Share Document