Investigation of the Properties of the Heavy Scintillating Fibers for Their Potential Use in Hadron Therapy Monitoring

2019 ◽  
pp. 195-210 ◽  
Author(s):  
K. Rusiecka ◽  
J. Kasper ◽  
A. Magiera ◽  
A. Stahl ◽  
A. Wrońska
Keyword(s):  
Therapy Monitoring ◽  
Hadron Therapy ◽  
Scintillating Fibers ◽  
Potential Use

scholarly journals PV-0562: Hadron-therapy monitoring with in-beam PET: measurements and simulations of the INSIDE PET scanner

2016 ◽  
Vol 119 ◽  
pp. S270 ◽  
Author(s):  
F. Pennazio ◽  
M. Bisogni ◽  
N. Camarlinghi ◽  
P. Cerello ◽  
E. Fiorina ◽  
...  
Keyword(s):  
Therapy Monitoring ◽  
Hadron Therapy

279 COMPARISON OF PROMPT-GAMMA AND POSITRON IMAGING FOR HADRON-THERAPY MONITORING

2012 ◽  
Vol 102 ◽  
pp. S145-S146
Author(s):  
I. Torres-Espallardo ◽  
J. Gillam ◽  
P. Solevi ◽  
G. Llosa Lacer ◽  
V. Stankova ◽  
...  
Keyword(s):  
Therapy Monitoring ◽  
Prompt Gamma ◽  
Hadron Therapy

scholarly journals Acoustic Bragg Peak Localization in Proton Therapy Treatment: Simulation Studies

Proceedings ◽  
2019 ◽  
Vol 42 (1) ◽  
pp. 71
Author(s):  
Jorge Otero ◽  
Ivan Felis ◽  
Miguel Ardid ◽  
Alicia Herrero ◽  
José A. Merchán
Keyword(s):  
Energy Deposition ◽  
Bragg Peak ◽  
Local Heating ◽  
Therapy Monitoring ◽  
Thermal Source ◽  
The Finite Element Method ◽  
Hadron Therapy ◽  
Beam Monitoring ◽  
The Brain ◽  
Therapy Treatment

A full chain simulation of the acoustic hadron therapy monitoring for brain tumors is presented in this work. For the study, a proton beam of 100 MeV was considered. In the first stage, Geant4 was used to simulate the energy deposition and to study the behavior of the Bragg peak. The energy deposition in the medium produced local heating that can be considered instantaneous with respect to the hydrodynamic time scale producing a sound pressure wave. The resulting thermoacoustic signal was subsequently obtained by solving the thermoacoustic equation. The acoustic propagation was simulated by the Finite Element Method (FEM) in the brain and the skull, where a set of piezoelectric sensors were placed. Lastly, the final received signals in the sensors were processed in order to reconstruct the position of the thermal source and, thus, to determine the feasibility and accuracy of acoustic beam monitoring in hadron therapy.

scholarly journals Role of Extracellular Vesicle-Based Cell-to-Cell Communication in Multiple Myeloma Progression

Cells ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 3185
Author(s):  
Ilaria Saltarella ◽  
Aurelia Lamanuzzi ◽  
Benedetta Apollonio ◽  
Vanessa Desantis ◽  
Giulia Bartoli ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Therapy Monitoring ◽  
Cell Communication ◽  
Extracellular Vesicle ◽  
Therapeutic Agents ◽  
Disease Classification ◽  
Biologically Active ◽  
Clinical Biomarkers ◽  
Potential Use

Multiple myeloma (MM) progression closely depends on the bidirectional crosstalk between tumor cells and the surrounding microenvironment, which leads to the creation of a tumor supportive niche. Extracellular vesicles (EVs) have emerged as key players in the pathological interplay between the malignant clone and near/distal bone marrow (BM) cells through their biologically active cargo. Here, we describe the role of EVs derived from MM and BM cells in reprogramming the tumor microenvironment and in fostering bone disease, angiogenesis, immunosuppression, drug resistance, and, ultimately, tumor progression. We also examine the emerging role of EVs as new therapeutic agents for the treatment of MM, and their potential use as clinical biomarkers for early diagnosis, disease classification, and therapy monitoring.

On the detector arrangement for in-beam PET for hadron therapy monitoring

2006 ◽  
Vol 51 (9) ◽  
pp. 2143-2163 ◽  
Author(s):  
Paulo Crespo ◽  
Georgy Shakirin ◽  
Wolfgang Enghardt
Keyword(s):  
Therapy Monitoring ◽  
Hadron Therapy ◽  
Detector Arrangement

A Tracking Compton-Scattering Imaging System for Hadron Therapy Monitoring

2010 ◽  
Vol 57 (1) ◽  
pp. 144-150 ◽  
Author(s):  
Mirela Frandes ◽  
Andreas Zoglauer ◽  
Voichita Maxim ◽  
Rémy Prost
Keyword(s):  
Compton Scattering ◽  
Imaging System ◽  
Therapy Monitoring ◽  
Hadron Therapy
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