From Dynamic State Machines to Promela

Author(s):  
Massimo Benerecetti ◽  
Ugo Gentile ◽  
Stefano Marrone ◽  
Roberto Nardone ◽  
Adriano Peron ◽  
...  
Keyword(s):  
2017 ◽  
Vol 133 ◽  
pp. 116-153 ◽  
Author(s):  
M. Benerecetti ◽  
R. De Guglielmo ◽  
U. Gentile ◽  
S. Marrone ◽  
N. Mazzocca ◽  
...  

Author(s):  
Roberto Nardone ◽  
Ugo Gentile ◽  
Adriano Peron ◽  
Massimo Benerecetti ◽  
Valeria Vittorini ◽  
...  

Author(s):  
Burton B. Silver

Sectioned tissue rarely indicates evidence of what is probably a highly dynamic state of activity in mitochondria which have been reported to undergo a variety of movements such as streaming, divisions and coalescence. Recently, mitochondria from the rat anterior pituitary have been fixed in a variety of configurations which suggest that conformational changes were occurring at the moment of fixation. Pinocytotic-like vacuoles which may be taking in or expelling materials from the surrounding cell medium, appear to be forming in some of the mitochondria. In some cases, pores extend into the matrix of the mitochondria. In other forms, the remains of what seems to be pinched off vacuoles are evident in the mitochondrial interior. Dense materials, resembling secretory droplets, appear at the junction of the pores and the cytoplasm. The droplets are similar to the secretory materials commonly identified in electron micrographs of the anterior pituitary.


Author(s):  
Irina Bystrova ◽  
E. Danil'chuk ◽  
Boris Podkopaev

The problem of constructing a diagnostic model for a network S consisting of a number of digital automata is considered, provided that the diagnostic models of all network components are known. It is assumed that these models are given by systems of logical equations, and the errors to be detected are localized in any but a single component of the network.


Author(s):  
Parag A Pathade ◽  
Vinod A Bairagi ◽  
Yogesh S. Ahire ◽  
Neela M Bhatia

‘‘Proteomics’’, is the emerging technology leading to high-throughput identification and understanding of proteins. Proteomics is the protein equivalent of genomics and has captured the imagination of biomolecular scientists, worldwide. Because proteome reveals more accurately the dynamic state of a cell, tissue, or organism, much is expected from proteomics to indicate better disease markers for diagnosis and therapy monitoring. Proteomics is expected to play a major role in biomedical research, and it will have a significant impact on the development of diagnostics and therapeutics for cancer, heart ailments and infectious diseases, in future. Proteomics research leads to the identification of new protein markers for diagnostic purposes and novel molecular targets for drug discovery.  Though the potential is great, many challenges and issues remain to be solved, such as gene expression, peptides, generation of low abundant proteins, analytical tools, drug target discovery and cost. A systematic and efficient analysis of vast genomic and proteomic data sets is a major challenge for researchers, today. Nevertheless, proteomics is the groundwork for constructing and extracting useful comprehension to biomedical research. This review article covers some opportunities and challenges offered by proteomics.   


Author(s):  
Sandip Tiwari

Information is physical, so its manipulation through devices is subject to its own mechanics: the science and engineering of behavioral description, which is intermingled with classical, quantum and statistical mechanics principles. This chapter is a unification of these principles and physical laws with their implications for nanoscale. Ideas of state machines, Church-Turing thesis and its embodiment in various state machines, probabilities, Bayesian principles and entropy in its various forms (Shannon, Boltzmann, von Neumann, algorithmic) with an eye on the principle of maximum entropy as an information manipulation tool. Notions of conservation and non-conservation are applied to example circuit forms folding in adiabatic, isothermal, reversible and irreversible processes. This brings out implications of fluctuation and transitions, the interplay of errors and stability and the energy cost of determinism. It concludes discussing networks as tools to understand information flow and decision making and with an introduction to entanglement in quantum computing.


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