On the Application of Flexible Designs When Searching for the Better of Two Anticancer Treatments

2020 ◽  
pp. 211-243
Author(s):  
Christina Kunz ◽  
Lutz Edler
Keyword(s):  
Flexible Designs

scholarly journals The prototypes of nanozyme-based nanorobots

2020 ◽  
Vol 6 (6) ◽  
pp. 223-244
Author(s):  
Jiaying Xie ◽  
Yiliang Jin ◽  
Kelong Fan ◽  
Xiyun Yan
Keyword(s):  
Functional Nanomaterials ◽  
Promising Candidate ◽  
Future Directions ◽  
Complex Tasks ◽  
Logic Control ◽  
The Future ◽  
Flexible Designs

AbstractArtificial nanorobot is a type of robots designed for executing complex tasks at nanoscale. The nanorobot system is typically consisted of four systems, including logic control, driving, sensing and functioning. Considering the subtle structure and complex functionality of nanorobot, the manufacture of nanorobots requires designable, controllable and multi-functional nanomaterials. Here, we propose that nanozyme is a promising candidate for fabricating nanorobots due to its unique properties, including flexible designs, controllable enzyme-like activities, and nano-sized physicochemical characters. Nanozymes may participate in one system or even combine several systems of nanorobots. In this review, we summarize the advances on nanozyme-based systems for fabricating nanorobots, and prospect the future directions of nanozyme for constructing nanorobots. We hope that the unique properties of nanozymes will provide novel ideas for designing and fabricating nanorobotics.

Flexible designs for phase II comparative clinical trials involving two response variables

2014 ◽  
Vol 34 (2) ◽  
pp. 197-214 ◽  
Author(s):  
S. Bersimis ◽  
A. Sachlas ◽  
T. Papaioannou
Keyword(s):  
Clinical Trials ◽  
Phase Ii ◽  
Flexible Designs ◽  
Response Variables

scholarly journals A new stress-based topology optimization approach for finding flexible structures

2021 ◽  
Author(s):  
Martin Noack ◽  
Arnold Kühhorn ◽  
Markus Kober ◽  
Matthias Firl
Keyword(s):  
Topology Optimization ◽  
Stress State ◽  
Design Space ◽  
Flexible Structures ◽  
Optimization Approach ◽  
Principal Stresses ◽  
Output Displacement ◽  
Design Concepts ◽  
Flexible Designs ◽  
Gauss Points

AbstractThis paper presents a new FE-based stress-related topology optimization approach for finding bending governed flexible designs. Thereby, the knowledge about an output displacement or force as well as the detailed mounting position is not necessary for the application. The newly developed objective function makes use of the varying stress distribution in the cross section of flexible structures. Hence, each element of the design space must be evaluated with respect to its stress state. Therefore, the method prefers elements experiencing a bending or shear load over elements which are mainly subjected to membrane stresses. In order to determine the stress state of the elements, we use the principal stresses at the Gauss points. For demonstrating the feasibility of the new topology optimization approach, three academic examples are presented and discussed. As a result, the developed sensitivity-based algorithm is able to find usable flexible design concepts with a nearly discrete 0 − 1 density distribution for these examples.

It All Works Out in the End

2021 ◽  
pp. 73-94
Author(s):  
Rebecca Lynn Chism ◽  
Carine Graff
Keyword(s):  
Qualitative Research ◽  
Quantitative Research ◽  
Online Survey ◽  
Language Learner ◽  
Time Constraints ◽  
Online Surveys ◽  
Midwestern University ◽  
Flexible Designs ◽  
Current Article ◽  
And Training

Qualitative research enables flexible designs unlike quantitative research, but those designs can be modified up to a point. It sometimes happens that the study at hand takes an unexpected turn of events and the researchers have then to find ways to cope with the changes. When the matter being investigated involves online surveys, there is even more leeway for uncertainty, as difficulties such as finding participants and time constraints may arise. This chapter presents a study conducted by two researchers in an American midwestern university and the challenges they encountered after answering a call for papers about technology and language learner psychology. They used an online survey to inquire about students' experience in an online language course. However, the lack of time intertwined with unexpected events involved readjustments and a need for more research and training. In the current article, the researchers share their project timeline, the issues they encountered, and offer some solutions.

Flexible Designs

2006 ◽  
Author(s):  
Martin Posch ◽  
Peter Bauer ◽  
Werner Brannath
Keyword(s):  
Flexible Designs

Flexible Designs

2014 ◽  
pp. 383-398
Author(s):  
Martin Posch ◽  
Peter Bauer ◽  
Werner Brannath
Keyword(s):  
Flexible Designs

A Collective-Action Perspective on the Planning of Megaprojects

2017 ◽  
Author(s):  
Nuno Gil
Keyword(s):  
Collective Action ◽  
Resource Scarcity ◽  
Political Activity ◽  
Organizational Slack ◽  
Performance Targets ◽  
The Core ◽  
Local Searches ◽  
Flexible Designs ◽  
Conflicting Interests ◽  
The Uk

This chapter adopts a collective action perspective to study the planning of large infrastructure developments: so-called “megaprojects.” The research is grounded on the analysis of make-or-break issues that beset four megaprojects in the UK. First it is argued that megaprojects are organizational networks that at the core create large arenas of consensus-oriented collective action. The analysis shows how the conflation of resource scarcity, conflicting interests, and concerns with legitimacy complicates local searches for mutually consensual solutions and brings to the fore bargaining and political activity. The central contribution is a model that proposes a combination of four high-order coordination mechanisms for management to carry the actors along openly: relaxing performance targets, building organizational slack, espousing flexible designs, and creating a structure of umpires to settle disputes that could not be self-resolved. Implications for the megaproject performance debate are discussed.

Flexible Designs

2014 ◽  
Author(s):  
Martin Posch ◽  
Peter Bauer ◽  
Werner Brannath
Keyword(s):  
Flexible Designs
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