Lower Limbs Robotic Rehabilitation Case Study with Clinical Trials

Author(s):  
M. Bouri ◽  
E. Abdi ◽  
H. Bleuler ◽  
F. Reynard ◽  
O. Deriaz
2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Patrizia Poli ◽  
Giovanni Morone ◽  
Giulio Rosati ◽  
Stefano Masiero

Introduction. The role of robotics in poststroke patients’ rehabilitation has been investigated intensively. This paper presents the state-of-the-art and the possible future role of robotics in poststroke rehabilitation, for both upper and lower limbs.Materials and Methods. We performed a comprehensive search of PubMed, Cochrane, and PeDRO databases using as keywords “robot AND stroke AND rehabilitation.”Results and Discussion. In upper limb robotic rehabilitation, training seems to improve arm function in activities of daily living. In addition, electromechanical gait training after stroke seems to be effective. It is still unclear whether robot-assisted arm training may improve muscle strength, and which electromechanical gait-training device may be the most effective for walking training implementation.Conclusions. In the field of robotic technologies for stroke patients’ rehabilitation we identified currently relevant growing points and areas timely for developing research. Among the growing points there is the development of new easily transportable, wearable devices that could improve rehabilitation also after discharge, in an outpatient or home-based setting. For developing research, efforts are being made to establish the ideal type of treatment, the length and amount of training protocol, and the patient’s characteristics to be successfully enrolled to this treatment.


2020 ◽  
Vol 3 (A1) ◽  
pp. 1-114
Author(s):  
ISI-SENAI-CIMATEC Group

This Appendix 1 presents the clinical trials against COVID-19 registered in WHO and clinicaltrials.gov by United States of America database.


2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S93-S93
Author(s):  
A Rjoop ◽  
M Barukba ◽  
O Al Rusan

Abstract Introduction/Objective Hemophagocytic Syndromes are a cluster of disorders related to cytotoxic dysfunction of T/NK-cells and are mainly subdivided into Primary (familial) and Secondary (acquired) forms, with the latter usually linked to patients with viral infections; including EBV, CMV among many others. A myriad of other causes have been associated with hemophagocytic lymphohistiocytosis (HLH), most notably systemic inflammatory conditions; especially Juvenile Rheumatoid Arthritis and hematolymphoid malignancies particularly T/NK-cell lymphomas. Methods/Case Report A previously healthy 7-year-old boy, presented to the ER with fever and a skin rash over both lower limbs of 1 week duration. Two weeks prior he was tested for COVID-19 and was found to be positive. Physical examination further revealed slightly palpable liver and spleen. CBC was done and exhibited pancytopenia, further testing showed elevated LDH, hyperferritinemia and hypertriglyceridemia. However, serological testing for rheumatological conditions was unremarkable. Imaging studies were done and were noncontributory. Subsequently, a bone marrow aspirate and biopsy were done. The bone marrow aspirate showed afew histiocytes engulfing red blood cells and nuclear debris (hemophagocytic cells), complete trilineage maturation and normal M:E ratio of 3:1. Trephine biopsy was hypocellular for age and estimated at about 70%, composed of myeloid and erythroid precursors with various degrees of maturation. Megakaryocytes were adequate in number and showed normal morphology. Extensive histiocytic infiltration as highlighted by CD68 immunostain and focal phagocytosis were identified. CD34 highlighted <5% blasts, PAS special stain showed no fungal elements and no fibrosis was evident by Reticulin special stain. The background was devoid of lymphoid aggregates or granulomas. Stainable iron stores were depleted. No sideroblasts were identified. The patient was treated with corticosteroid and showed marked improvement and was discharged after 3 days. Results (if a Case Study enter NA) NA Conclusion Hemophagocytic lymphohistiocytosis can be a critical sequela of COVID-19 infection. Suggested mechanisms include impaired/delayed T-cell response and elevated levels of several inflammatory cytokines. Clinical suspesion is important in the diagnosis of these cases. Further study of this correlation is needed as we explore clinical sequelae of COVID-19 infection.


Pilomatricoma is a rare, benign skin tumour arising from the hair matrix. The usual locations are the head and neck. Localization in the lower limbs is exceptional. The diagnosis of certainty is histological. Treatment is complete surgical removal to avoid recurrence. We report in this article the case of a rare localization of a pilomatricoma on the right leg, in a 25-year-old patient operated with complete surgical removal. The postoperative course was simple and without recurrence after 2 months of follow-up.


2021 ◽  
Vol 9 (01) ◽  
pp. 11-18
Author(s):  
Teguh Pradana ◽  
Moch. Zul Ilmi ◽  
Teguh Arifianto

Herbal medicine is a medicine from natural ingredients whose properties have not been scientifically proven, in other words, it has not been subjected to clinical or clinical trials, but its properties are trusted by people based on experience. And at this time many herbal products are marketed in general, and not a few people are confused to choose the right herbal medicine according to their circumstances, so people have to consult or ask before choosing, and make the store experience a long queue on customers. Therefore an expert system is needed for herbal medicine so that people can choose the right herbal medicine according to their circumstances or conditions, and this system can reduce the queue at the herbal medicine shop customers. Expert system built in this study uses the forward chaining method. Case study for the system that is "Pasuruan herbal shop fan" which contained 70 types of herbal medicine, the results of tests conducted by this system are in accordance with the diagnosis.


Author(s):  
Robert Bogue

Purpose This paper aims to provide an insight into the emerging use of robots in the rehabilitation of sufferers from strokes and other neurological impediments. Design/methodology/approach This considers research, clinical trials and commercial products. Following an introduction, it explains brain neuroplasticity and its role in rehabilitation and then discusses the use of robots in the restoration of upper limb and hand movement in stroke and traumatic injury patients. Robotic techniques aimed at restoring ambulatory ability are then discussed, followed by examples of the application of brain–computer interface technology to robotic rehabilitation. Finally, concluding comments are drawn. Findings Research has shown that robotic techniques can assist in the restoration of functionality to partially or fully paralysed upper and lower limbs. A growing number of commercial exoskeleton and end-effector robotic products have been launched which are augmenting conventional rehabilitation therapies. These systems frequently include interactive computer games and tasks which encourage repetitive use and allow patients to monitor their progress. Trials which combine robotics with brain–computer interface technology have yielded encouraging and unexpectedly positive results. Originality/value This provides details of the increasingly important role played by robots in the rehabilitation of patients suffering from strokes and other neurological disorders.


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