Low-Rank Transfer Learning

In recent years, machine learning techniques have been proven to be a promising tool for early fault detection of rolling bearings. In many actual applications, however, bearing whole-life data are not easy to be historically accumulated, while insufficient data may result in training a detection model that is not good enough. If utilizing the available data under different working conditions to facilitate model training, the data distribution of different bearings are usually quite different, which does not meet the precondition of i n d e p e n d e n t a n d i d e n t i c a l d i s t r i b u t i o n ( i . i . d ) and tends to cause performance reduction. In addition, disturbed by the unstable noise under complex conditions, most of the current detection methods are inclined to raise false alarms, so that the reliability of detection results needs to be improved. To solve these problems, a robust detection method for bearings early fault is proposed based on deep transfer learning. The method includes offline stage and online stage. In the offline stage, by introducing a deep auto-encoder network with domain adaptation, the distribution inconsistency of normal state data among different bearings can be weakened, then the common feature representation of the normal state is obtained. With the extracted common features, a new state assessment method based on the robust deep auto-encoder network is proposed to evaluate the boundary between normal state and early fault state in the low-rank feature space. By training a support vector machine classifier, the detection model is established. In the online stage, along with the data batch arriving sequentially, the features of target bearing are extracted using the common representation learnt in the offline stage, and online detection is conducted by feeding them into the SVM model. Experimental results on IEEE PHM Challenge 2012 bearing dataset and XJTU-SY dataset show that the proposed approach outperforms several state-of-the-art detection methods in terms of detection accuracy and false alarm rate.

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Integration and transfer learning of single-cell transcriptomes via cFIT

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.2024383118 ◽

2021 ◽

Vol 118 (10) ◽

pp. e2024383118

Author(s):

Minshi Peng ◽

Yue Li ◽

Brie Wamsley ◽

Yuting Wei ◽

Kathryn Roeder

Keyword(s):

Single Cell ◽

Transfer Learning ◽

Developmental Stages ◽

Common Factor ◽

Nonnegative Matrix ◽

Cell Types ◽

Brain Cell ◽

Low Rank ◽

Model Parameters ◽

Factor Space

Large, comprehensive collections of single-cell RNA sequencing (scRNA-seq) datasets have been generated that allow for the full transcriptional characterization of cell types across a wide variety of biological and clinical conditions. As new methods arise to measure distinct cellular modalities, a key analytical challenge is to integrate these datasets or transfer knowledge from one to the other to better understand cellular identity and functions. Here, we present a simple yet surprisingly effective method named common factor integration and transfer learning (cFIT) for capturing various batch effects across experiments, technologies, subjects, and even species. The proposed method models the shared information between various datasets by a common factor space while allowing for unique distortions and shifts in genewise expression in each batch. The model parameters are learned under an iterative nonnegative matrix factorization (NMF) framework and then used for synchronized integration from across-domain assays. In addition, the model enables transferring via low-rank matrix from more informative data to allow for precise identification in data of lower quality. Compared with existing approaches, our method imposes weaker assumptions on the cell composition of each individual dataset; however, it is shown to be more reliable in preserving biological variations. We apply cFIT to multiple scRNA-seq datasets of developing brain from human and mouse, varying by technologies and developmental stages. The successful integration and transfer uncover the transcriptional resemblance across systems. The study helps establish a comprehensive landscape of brain cell-type diversity and provides insights into brain development.

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