The Role of Inflammation in Autism Spectrum Disorder

2015 ◽  
pp. 275-312 ◽  
Author(s):  
Casara Jean Ferretti ◽  
Eric Hollander
Keyword(s):  
Autism Spectrum Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder

The role of eye contact in young children’s judgments of others’ visibility: A comparison of preschoolers with and without autism spectrum disorder

2021 ◽  
Vol 89 ◽  
pp. 106075
Author(s):  
Allie Khalulyan ◽  
Katie Byrd ◽  
Jonathan Tarbox ◽  
Alexandra Little ◽  
Henrike Moll
Keyword(s):  
Autism Spectrum Disorder ◽  
Eye Contact ◽  
Autism Spectrum ◽  
Spectrum Disorder

scholarly journals A systematic review and meta-analysis of studies on metaphor comprehension in individuals with autism spectrum disorder: Do task properties matter?

2019 ◽  
Vol 40 (6) ◽  
pp. 1421-1454 ◽  
Author(s):  
Tamar Kalandadze ◽  
Valentina Bambini ◽  
Kari-Anne B. Næss
Keyword(s):  
Systematic Review ◽  
Autism Spectrum Disorder ◽  
Syntactic Structure ◽  
Meta Analysis ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Response Format ◽  
Metaphor Comprehension ◽  
The Relationship

AbstractIndividuals with autism spectrum disorder (ASD) often experience difficulty in comprehending metaphors compared to individuals with typical development (TD). However, there is a large variation in the results across studies, possibly related to the properties of the metaphor tasks. This preregistered systematic review and meta-analysis (a) explored the properties of the metaphor tasks used in ASD research, and (b) investigated the group difference between individuals with ASD and TD on metaphor comprehension, as well as the relationship between the task properties and any between-study variation. A systematic search was undertaken in seven relevant databases. Fourteen studies fulfilled our predetermined inclusion criteria. Across tasks, we detected four types of response format and a great variety of metaphors in terms of familiarity, syntactic structure, and linguistic context. Individuals with TD outperformed individuals with ASD on metaphor comprehension (Hedges’ g = −0.63). Verbal explanation response format was utilized in the study showing the largest effect size in the group comparison. However, due to the sparse experimental manipulations, the role of task properties could not be established. Future studies should consider and report task properties to determine their role in metaphor comprehension, and to inform experimental paradigms as well as educational assessment.

Learning Difficulties and Oxidative Stress in Autism Spectrum Disorder: A Review of the Role of Nutritional Interventions

2021 ◽  
Vol 15 (4) ◽  
pp. 422-434
Author(s):  
Maryam Turkestani ◽  
Norah Aldosiry ◽  
Najat Hamed ◽  
Ramesa Shafi Bhat ◽  
Afaf El-Ansary
Keyword(s):  
Oxidative Stress ◽  
Autism Spectrum Disorder ◽  
Learning Difficulties ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Nutritional Interventions ◽  
And Oxidative Stress

scholarly journals Role of fruits, grains, and seafood consumption in blood cadmium concentrations of Jamaican children with and without Autism Spectrum Disorder

2014 ◽  
Vol 8 (9) ◽  
pp. 1134-1145 ◽  
Author(s):  
Mohammad H. Rahbar ◽  
Maureen Samms-Vaughan ◽  
Aisha S. Dickerson ◽  
Katherine A. Loveland ◽  
Manouchehr Ardjomand-Hessabi ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Seafood Consumption ◽  
Blood Cadmium

scholarly journals Hypothesis: The Role of Sterols in Autism Spectrum Disorder

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Ryan W. Y. Lee ◽  
Elaine Tierney
Keyword(s):  
Autism Spectrum Disorder ◽  
Sonic Hedgehog ◽  
Autism Spectrum ◽  
Membrane Lipid ◽  
Molecular Techniques ◽  
Spectrum Disorder ◽  
Advanced Imaging ◽  
Opitz Syndrome ◽  
Membrane Physiology

A possible role for sterols in the development of autism spectrum disorder (ASD) has not been proven, but studies in disorders of sterol biosynthesis, chiefly Smith-Lemli-Opitz syndrome (SLOS), enable hypotheses on a causal relationship to be discussed. Advances in genetic technology coupled with discoveries in membrane physiology have led to renewed interest for lipids in the nervous system. This paper hypothesizes on the role of sterol dysfunction in ASD through the framework of SLOS. Impaired sonic hedgehog patterning, alterations in membrane lipid rafts leading to abnormal synaptic plasticity, and impaired neurosteroid synthesis are discussed. Potential therapeutic agents include the development of neuroactive steroid-based agents and enzyme-specific drugs. Future investigations should reveal the specific mechanisms underlying sterol dysfunction in neurodevelopmental disorders by utilizing advanced imaging and molecular techniques.

The Formation of Postsecondary Expectations Among Parents of Youth With Autism Spectrum Disorder

2019 ◽  
Vol 35 (2) ◽  
pp. 118-128 ◽  
Author(s):  
Anne V. Kirby ◽  
Nancy Bagatell ◽  
Grace T. Baranek
Keyword(s):  
Autism Spectrum Disorder ◽  
Transition To Adulthood ◽  
Autism Spectrum ◽  
Parent Expectations ◽  
Spectrum Disorder ◽  
Future Research ◽  
Structured Interviews ◽  
The Family ◽  
Postsecondary Expectations

Research suggests higher parent expectations can predict more independent outcomes of youth with autism spectrum disorder (ASD), yet little is known about how parents’ expectations are formed. To gain an understanding of their formation, we conducted semi-structured interviews with seven parents of adolescents with ASD. Three main types of influences on parent expectations were identified: factors related to the youth, to the parent, and to social and societal forces external to the family. Although not directly probed, all of the participants also discussed their approaches to planning for the future, suggesting a connection with their expectations. These findings contribute to a growing body of literature on the role of parent expectations during the transition to adulthood. Future research and clinical practice implications include designing interventions aimed at expanding parent expectations in addition to approaches directly preparing youth with ASD for adulthood as a means to improve outcomes.

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