Beyond Membrane Protein Structure: Drug Discovery, Dynamics and Difficulties

2016 ◽  
pp. 161-181 ◽  
Author(s):  
Philip C. Biggin ◽  
Matteo Aldeghi ◽  
Michael J. Bodkin ◽  
Alexander Heifetz
Keyword(s):  
Protein Structure ◽  
Drug Discovery ◽  
Membrane Protein ◽  
Membrane Protein Structure

Order-disorder transitions of cytoplasmic N-termini in the mechanisms of P-type ATPases

2020 ◽  
Author(s):  
Khondker Rufaka Hossain ◽  
Daniel Clayton ◽  
Sophia C Goodchild ◽  
Alison Rodger ◽  
Richard James Payne ◽  
...  
Keyword(s):  
Protein Structure ◽  
Membrane Protein ◽  
Structure And Function ◽  
Membrane Protein Structure ◽  
Protein Structure And Function ◽  
Lipid Environment ◽  
Membrane Pumps ◽  
And Function ◽  
P Type

Membrane protein structure and function are modulated via interactions with their lipid environment. This is particularly true for the integral membrane pumps, the P-type ATPases. These ATPases play vital roles...

scholarly journals Using a SMALP platform to determine a sub-nm single particle cryo-EM membrane protein structure

2018 ◽  
Vol 1860 (2) ◽  
pp. 378-383 ◽  
Author(s):  
Mayuriben Parmar ◽  
Shaun Rawson ◽  
Charlotte A. Scarff ◽  
Adrian Goldman ◽  
Timothy R. Dafforn ◽  
...  
Keyword(s):  
Protein Structure ◽  
Membrane Protein ◽  
Single Particle ◽  
Membrane Protein Structure

CHAPTER 18. Helical Membrane Protein Structure: Strategy for Success

2014 ◽  
pp. 353-370
Author(s):  
Nabanita Das ◽  
Dylan T. Murray ◽  
Yimin Miao ◽  
Timothy A. Cross
Keyword(s):  
Protein Structure ◽  
Membrane Protein ◽  
Membrane Protein Structure
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