Designer Systems of Systems: A Rational Integrated Approach of System Engineering to Tailored Aerodynamics, Aeroelasticity, Aero-viscoelasticity, Stability, Control, Geometry, Materials, Structures, Propulsion, Performance, Sizing, Weight, Cost

The availability of reliable herbal formulations is essential in order to assure the maximal activity and to limit unwanted side-effects. The correct concentration of declared components of herbal products is a matter of health legislation and regulation, but is still a topic under debate in the field of quality control assessment. In the present work specific constituents of artichoke leaf extracts, considered as a test herbal product, were measured by standard spectrophotometric and HPLC methods (for quantitative determination of some components only), and results were correlated with the ESI-MS (showing the full metabolomic fingerprint). Phytocomplex stability over time was also investigated in batches submitted to different storage conditions. The results indicated excellent agreement between the two approaches in the measurement of total caffeoylquinic acids and chlorogenic acid contents, but the metabolomic ESI-MS method approach provides a more complete evaluation and monitoring of the composition of a herbal product, without focusing only on a single/few compound measurements. Therefore, the ESI-MS method can be proposed for the evaluation of the quality of complex matrices, such as those in a phytocomplex. Another aspect lies in the possibility to obtain a broad-spectrum stability control of herbal formulations, requiring minimal sample pre-processing procedures.

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Open Interoperable Autonomous Computer-Based Systems, Systems-of-Systems and Proof-Based System Engineering

Complex Systems Design & Management ◽

10.1007/978-3-642-15654-0_19 ◽

2010 ◽

pp. 259-278

Author(s):

Gérard Lann ◽

Paul Simon

Keyword(s):

System Engineering ◽

Systems Of Systems ◽

Computer Based

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Managing Requirements: For an Integrated Approach from System Engineering to Project Management

Progress in Pattern Recognition, Image Analysis, Computer Vision, and Applications - Lecture Notes in Computer Science ◽

10.1007/978-3-662-44739-0_18 ◽

2014 ◽

pp. 142-149 ◽

Cited By ~ 1

Author(s):

Michel Malbert ◽

Daniel Estève ◽

Claude Baron ◽

Philippe Esteban ◽

Rui Xue

Keyword(s):

Project Management ◽

Integrated Approach ◽

System Engineering

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System Engineering and PLM as an integrated approach for industry collaboration management

IFAC Proceedings Volumes ◽

10.3182/20120523-3-ro-2023.00205 ◽

2012 ◽

Vol 45 (6) ◽

pp. 1135-1140 ◽

Cited By ~ 4

Author(s):

Mourad. Messaadia ◽

Farouk. Belkadi ◽

Benoit. Eynard ◽

Abd-El-Kader. Sahraoui

Keyword(s):

Integrated Approach ◽

System Engineering ◽

Industry Collaboration ◽

Collaboration Management

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Case-based reasoning and system design: An integrated approach based on ontology and preference modeling

Artificial intelligence for engineering design analysis and manufacturing ◽

10.1017/s0890060413000498 ◽

2014 ◽

Vol 28 (1) ◽

pp. 49-69 ◽

Cited By ~ 5

Author(s):

Juan Camilo Romero Bejarano ◽

Thierry Coudert ◽

Elise Vareilles ◽

Laurent Geneste ◽

Michel Aldanondo ◽

...

Keyword(s):

System Design ◽

Similarity Measures ◽

Integrated Approach ◽

System Engineering ◽

Retrieval Algorithm ◽

Case Based Reasoning ◽

Requirements Definition ◽

Definition Of ◽

Similar Solutions ◽

Case Based

AbstractThis paper addresses the fulfillment of requirements related to case-based reasoning (CBR) processes for system design. Considering that CBR processes are well suited for problem solving, the proposed method concerns the definition of an integrated CBR process in line with system engineering principles. After the definition of the requirements that the approach has to fulfill, an ontology is defined to capitalize knowledge about the design within concepts. Based on the ontology, models are provided for requirements and solutions representation. Next, a recursive CBR process, suitable for system design, is provided. Uncertainty and designer preferences as well as ontological guidelines are considered during the requirements definition, the compatible cases retrieval, and the solution definition steps. This approach is designed to give flexibility within the CBR process as well as to provide guidelines to the designer. Such questions as the following are conjointly treated: how to guide the designer to be sure that the requirements are correctly defined and suitable for the retrieval step, how to retrieve cases when there are no available similarity measures, and how to enlarge the research scope during the retrieval step to obtain a sufficient panel of solutions. Finally, an example of system engineering in the aeronautic domain illustrates the proposed method. A testbed has been developed and carried out to evaluate the performance of the retrieval algorithm and a software prototype has been developed in order to test the approach. The outcome of this work is a recursive CBR process suitable to engineering design and compatible with standards. Requirements are modeled by means of flexible constraints, where the designer preferences are used to express the flexibility. Similar solutions can be retrieved even if similarity measures between features are not available. Simultaneously, ontological guidelines are used to guide the process and to aid the designer to express her/his preferences.

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