A systematic ethnobotanical review of Adhatoda vasica (L.), Nees.

Adhatoda vasica (L.), Nees belonging to the family Acanthaceae is a shrub with opposite ascending branches. The plant has been used in the indigenous system of medicine in India for near about 2500 years. It is a well-known plant as a drug in Ayurvedic and Unani medicines. Traditionally it was used for the treatment of various acute and chronic diseases and showed strong pharmacological activity particularly for bronchial infections, cough, bacterial infections, reproductive disorders, cardiac diseases and many more. Various phytochemicals like alkaloids, flavonoids, tannins, etc. were obtained from Adhatoda vasica (A. vasica). The active constituent of the plant is vasicine, l-vasicinone, deoxyvasicine, maiontone, vasicinolone and vasicinol etc. This review consists of updated information on the phyto-constituents isolated from A. vasica and their potential role in the treatment of various ailments traditionally and medically. Based on the critical review it was concluded that there is not sufficient scientifically strong evidence to explain that A. vasica extract, could be harmful to human beings especially in pregnant women. Major data on traditional uses as well as toxicological studies, evaluated various correctness, relevance, importance, and reliability for the overall evaluation of A. vasica safety. Numerous clinical trials are conducted around the globe on the herbal formulations of vasaka. This review includes strong data about phytochemical and ethnopharmacological studies that indicate that A. vasica is a versatile native plant of the Indian subcontinent having a commercial reputation and thus can be encouraged for diversified applications like medicinal and other potential uses.

Pharmacy, the continuously expanding field of science

Originating from the traditional herbal formulations, nowadays, Pharmacy covers all the disciplines focusing on the behavior of complex pharmaceutical forms, drug-releasing systems, and active compounds in the human body. Masters of pharmaceutical sciences must know the basics of pharmaceutical chemistry, pharmaceutical technology, biotechnology, biology, physiology, pharmacology, and toxicology.

A Review Article on the Therapeutic Potential of Medicinal Plants for Prevention and Treatment of secondary infection in patients with COVID-19

: COVID-19 is an infectious disease, caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) that is rapidly spreading all over the world and responsible for the international health crisis. In an earlier period, various synthetic antiviral drugs and clinical therapies have been used to control the viral infection but at present, there is no specific treatment available for COVID-19 infection. Several approaches like ritonavir, lopinavir, hydroxychloroquine, and chloroquine have been proposed. India is a hub of medicinal plants, so there is a chance to find out the way to combat the COVID-19 pandemic. The medicinal herbal formulations may enhance the immunity and come up with a powerful antiviral drug, which is an urgent need to control the outbreak of coronavirus. In this review article, we have discussed epidemiology, clinical outcomes, treatment, and prevention of this novel epidemic coronavirus from medicinal herbal formulations perspective. We have also emphasized the reported antiviral activity and immunity-boosting property of the Indian medicinal plants. This article also suggests that the drug or formulation obtained from medicinal plant sources may have low fatal outcomes, quick response, and safe in the management and prevention of this pandemic outbreak.

The Therapeutic Potential of Common Herbal and Nano-Based Herbal Formulations against Ovarian Cancer: New Insight into the Current Evidence

Ovarian cancer (OCa) is characterized as one of the common reasons for cancer-associated death in women globally. This gynecological disorder is chiefly named the “silent killer” due to lacking an association between disease manifestations in the early stages and OCa. Because of the disease recurrence and resistance to common therapies, discovering an effective therapeutic way against the disease is a challenge. According to documents, some popular herbal formulations, such as curcumin, quercetin, and resveratrol, can serve as an anti-cancer agent through different mechanisms. However, these herbal products may be accompanied by some pharmacological limitations, such as poor bioavailability, instability, and weak water solubility. On the contrary, using nano-based material, e.g., nanoparticles (NPs), micelles, liposomes, can significantly solve these limitations. Therefore, in the present study, we will summarize the anti-cancer aspects of these herbal and-nano-based herbal formulations with a focus on their mechanisms against OCa.

Prakaradi Yogas: The Traditional Immunomodulators

It’s a well-known fact that Prevention is better than cure. As children are the basic building block of future generation Its the need of situation and mandatory for all to take care of their health in this current pandemic situation. Childhood is considered as the most susceptible age for infection. So following the proper safety measures during pandemic Arogya can also be achieved by good physical and mental health with the use of different(Ayurveda formulations well explained about Prakaradi yogas in Arogya raksha kalpa Druma one of the classical Ayurveda paediatric book for children .Prakaradi yogas aims at achieving basis of life immunity through various herbal formulations. Immunomodulators are the herbal drugs that augment or improve the immune response and immunity is always a prime concern in childhood. In Arogya Raksha Kalpadrum it’s been explained well that herbal formulations can enhance immunity when taken accordingly from birth up to attainment of 12 years of age. Use of Immuno-modulatory measures starting from Jatamatravastha up to 12 years of age can fulfill the desired health and longevity. Tackles the expected dosha vaishamya, and stabilizes Agni when taken at right time.This article highlights the role of different Prakkaradi Yoga in children for healthy growth and development of child to improve the longevity and quality of life.

Natural Products: Ray of Hope for Anxiety Disorders

Background: Anxiety, a familiar form of psychiatric disorder, influences numerous persons throughout the world. These psychological disorders frequently need an enduring regime of recommended medicines and impose huge costs on human societies. For the last few decenniums, discovery in the field of natural neurophysiology garnered a lot of recognition because of its least side effects. Objective: Many people find it helpful to discover an effective herbal remedy for anxiety with fewer detrimental repercussions. The purpose of the present article is to report medicinal plant species used as anti-anxiety agents, which in turn, are helpful to develop new anti-anxiety herbal formulations. Method: An unlimited, semantic electronic and manual exploration of PubMed, Cumulative Index of Nursing and Allied Health Literature, ISI, Google Scholar, Elsevier's abstract and citation database, and the database libraries was carried using keywords such as medicinal plants, herbal drugs, traditional medicine, and anxiety for recognizing natural medications in the management of anxiety disorders. Results: Literary review collected the information of potential anti-anxiety plants. Data support the effectiveness of some popular herbal remedies by indicating high-quality scientific studies and support several clinically efficacious natural plants as anxiolytics. Conclusion: Evidence-based studies indicate that natural plant treatment is an efficient way to manage anxiety disorders; the benefits outweigh the risks.

Poly-Herbal Formulations: Current Status and Future Perspectives for Treatment of Various Complications

In customary medication, the greater part of infections has been treated by reveling of plant or plant items. As indicated by the Ayurveda individual herbs are deficient to accomplish an ideal restorative impact. To conquer this issue numerous spice structure in certain proportion is utilized that will give a superior restorative impact in better manner with decreased harmfulness. To grow such mediation, current examination will address about polyherbal formulation uses and its outline in treatment of different diseases and ailments. Home grown medications have existed worldwide since long time ago, therefore they bear history, and they were utilized in Chinese, Egyptian and Indian medications for different treatment. This review primarily centers around significance of polyherbal and its clinical importance.

Phytopharmaceutical potential of Anthocephalus cadamba (Roxb.)

Ever since ancient times, medicinal plants served as a great source of herbal formulations which can confer human civilization with preferential quality of life. Among them, some plants secured their position in mythologies, also highlighting Anthocephalus cadamba, a religious medicinal plant, belonging to the family Rubiaceae, mostly cultivated in tropical regions. Conventional medicinal system of India provides evidences regarding folk medicinal uses for the treatment of various ailments like inflammation, skin diseases, uterine complaints, blood disease and diarrhea etc. Phytochemical investigations revealed the presence of some biologically active compounds like flavonoids, alkaloids, coumarins, terpenoids, diterpenoids, triterpenes, glycosides, sterols, amides and fatty acids and these compounds were found to be accountable for various pharmacological activities such as antimicrobial, antipyretic, anti-inflammatory, analgesic, anticancerous, antidibetic, hypolipidemic, antihepatotoxic, antidiarrhoel, diuretic, laxative, antioxidant, immunomodulatory, wound healing etc.

Challenges, Advances and Opportunities of Herbal Medicines in Wound Healing: A Review

A large portion of the world's population relies on herbs for medical purposes today. About 25-30% of modern drugs are chemical intermediates derived from plant constituents. Traditional medicinal plant preparations are frequently utilised for wound healing, encompassing a wide range of skin-related disorders. In wound management, herbal medicine entails cleaning, debridement, and the creation of an environment that promotes natural healing. This review discusses wound, healing of the wound, allopathic treatment in wound healing, types of herbal medicines used in the treatment of wound healing and common excipients used in topical herbal formulations. In this article, we look at 15 plants that have been utilised as wound healers in traditional medicine around the world. This study is an attempt to search the difficulties and challenges of herbal formulations need for novel drug delivery system nanocarriers for herbal remedies with other nanotechnology strategies and techniques as a new drug delivery system and its future prospective. The purpose of this review is to examine the most common excipients used in herbal formulations, as well as various medicinal plants traditionally used in wound healing, wound healing difficulties and challenges, the use of nanotechnology in herbal formulation, the future scope of herbal medicines in wound healing, and a comparison of allopathy and herbal formulations.