An Integrated Ontology-Based Approach for Patent Classification in Medical Engineering

Author(s):  
Sandra Geisler ◽  
Christoph Quix ◽  
Rihan Hai ◽  
Sanchit Alekh
2018 ◽  
Author(s):  
Yingqian Wang ◽  
Xiaoxia Hu ◽  
Lingling Zhang ◽  
Chunli Zhu ◽  
Jie Wang ◽  
...  

Extracellular vesicles (EVs) are involved in the regulation of cell physiological activity and the reconstruction of extracellular environment. Matrix vesicles (MVs) are a type of EVs, and they participate in the regulation of cell mineralization. Herein, bioinspired MVs embedded with black phosphorus are functionalized with cell-specific aptamer (denoted as Apt-bioinspired MVs) for stimulating biomineralization. The aptamer can direct bioinspired MVs to targeted cells, and the increasing concentration of inorganic phosphate originated from the black phosphorus can facilitate cell biomineralization. The photothermal effect of the Apt-bioinspired MVs also positively affects mineralization. In addition, the Apt-bioinspired MVs display outstanding bone regeneration performance. Considering the excellent behavior of the Apt-bioinspired MVs for promoting biomineralization, our strategy provides a way of designing bionic tools for studying the mechanisms of biological processes and advancing the development of medical engineering.<br>


2000 ◽  
Vol 9 (3) ◽  
pp. 255-267 ◽  
Author(s):  
H. Fischer ◽  
M. Selig ◽  
J. Vagner ◽  
B. Vogel ◽  
E. Hempel ◽  
...  

2019 ◽  
Vol 951 (9) ◽  
pp. 25-39
Author(s):  
V.V. Zabavnikov ◽  
A.N. Kobiakov ◽  
S.V. Kovalev

Informational and analytical studying patent documentation shows the patenting situation either in general in a specific technological area or the patent activity of innovation entities, taking temporal dynamics and the territorial basis into account. Patent-information investigation was carried out in order to get acquainted with the level of photogrammetry technology development and determine its current application areas. Statistical and intellectual patent document text analysis was the basis for relevant data array grouped in 8680 patent families’ creation. The prepared report contains a graphical display of selected patent documents array, related to research topic, analytical and statistical processing. The level of inventive activity was assessed; the world patenting dynamics and location in this technical field were considered. The main groups on the International Patent Classification, as well as the main technological directions, where technical solutions related to the object of study to be patented, are identified. Information on the leading applicants/ patent holders in this technical field is provided; the list of the most cited patent documents is considered.


2018 ◽  
Vol 7 (4) ◽  
pp. 603-622 ◽  
Author(s):  
Leonardo Gutiérrez-Gómez ◽  
Jean-Charles Delvenne

Abstract Several social, medical, engineering and biological challenges rely on discovering the functionality of networks from their structure and node metadata, when it is available. For example, in chemoinformatics one might want to detect whether a molecule is toxic based on structure and atomic types, or discover the research field of a scientific collaboration network. Existing techniques rely on counting or measuring structural patterns that are known to show large variations from network to network, such as the number of triangles, or the assortativity of node metadata. We introduce the concept of multi-hop assortativity, that captures the similarity of the nodes situated at the extremities of a randomly selected path of a given length. We show that multi-hop assortativity unifies various existing concepts and offers a versatile family of ‘fingerprints’ to characterize networks. These fingerprints allow in turn to recover the functionalities of a network, with the help of the machine learning toolbox. Our method is evaluated empirically on established social and chemoinformatic network benchmarks. Results reveal that our assortativity based features are competitive providing highly accurate results often outperforming state of the art methods for the network classification task.


1972 ◽  
Vol 10 (4) ◽  
pp. 545-548 ◽  
Author(s):  
C. D. Ray
Keyword(s):  

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