Nuclear and Mitochondrial Marker-Based Diversity and Population Structuring of Indian Goats

Author(s):  
Sonika Ahlawat ◽  
Rekha Sharma
2012 ◽  
Author(s):  
Diane E. Claridge ◽  
John W. Durban ◽  
Phillip Morin ◽  
Gina Ylitalo ◽  
David Herman

2021 ◽  
Vol 11 (6) ◽  
pp. 2616-2629
Author(s):  
Jake Goodall ◽  
Kristen Marie Westfall ◽  
Hildur Magnúsdóttir ◽  
Snæbjörn Pálsson ◽  
Erla Björk Örnólfsdóttir ◽  
...  

2021 ◽  
Author(s):  
Yanina F. Briñoccoli ◽  
Luiz Jardim de Queiroz ◽  
Sergio Bogan ◽  
Ariel Paracampo ◽  
Paula E. Posadas ◽  
...  

2007 ◽  
Vol 292 (5) ◽  
pp. C1971-C1981 ◽  
Author(s):  
Emily Cordas ◽  
Anikó Náray-Fejes-Tóth ◽  
Géza Fejes-Tóth

Serum- and glucocorticoid-induced kinase-1 (SGK1) is involved in aldosterone-induced Na+ reabsorption by increasing epithelial Na+ channel (ENaC) activity in cortical collecting duct (CCD) cells, but its exact mechanisms of action are unknown. Although several potential targets such as Nedd4-2 have been described in expression systems, endogenous substrates mediating SGK1's physiological effects remain to be identified. In addition, subcellular localization studies of SGK1 have provided controversial results. We determined the subcellular location of SGK1 using SGK1-autofluorescent protein (AFP) fusion proteins. Rabbit CCD (RCCT-28A) cells were transiently transfected with a construct encoding for SGK1-AFP and were stained or cotransfected with markers for various subcellular compartments. In live cells, transiently expressed SGK1-AFP clearly colocalized with the mitochondrial marker rhodamine 123. Similarly, SGK1-AFP colocalized with the mitochondrial marker MitoTracker when stably expressed using a retroviral system in either RCCT-28A cells or the mammary epithelial cell line MCF10A. To determine which region of SGK1 is responsible for this subcellular localization, we generated RCCT-28A cell lines stably expressing SGK1 mutants. The results indicate that the NH2-terminal 60-amino acid region of SGK1 is necessary and sufficient for its subcellular localization. Localization of SGK1 to the mitochondria raises the possibility that SGK1 may play a role in regulating energy metabolism.


2012 ◽  
Vol 187 (1-2) ◽  
pp. 129-139 ◽  
Author(s):  
L.M. McInnes ◽  
A.P. Dargantes ◽  
U.M. Ryan ◽  
S.A. Reid

2019 ◽  
Vol 41 (1) ◽  
pp. 65 ◽  
Author(s):  
Barry J. Richardson

As a consequence of genetic studies of population structuring, the usefulness of subspecies has been questioned, with opinions divided. The situation is further confused by the use of varying species and subspecies concepts. Most alternatives require each taxon to be following an independent evolutionary trajectory. These include traditional approaches and the more recent phylogenetic species concept. The latter has led to large increases in the apparent number of taxa in some groups, though strong objections have been raised to this approach. An alternative, the ecological species concept, has been opposed by phylogeneticists. These two approaches are compared using morphological and genetic data from common wallaroo (Osphranter robustus) populations. The different taxonomies that might result (many species, one species with two subspecies, one species with no subspecies) can have significant consequences for legislative and management decisions. The ecological approach is considered preferable for subspecies and the present taxonomy is maintained. A potential location of the boundary between the wallaroo subspecies is proposed. How the use of the different subspecies definitions would affect legislative decisions is explored.


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