Towards a Systematic Evaluation of Generative Network Models

Lecture Notes in Computer Science - Algorithms and Models for the Web Graph ◽

10.1007/978-3-319-92871-5_8 ◽

2018 ◽

pp. 99-114 ◽

Cited By ~ 1

Author(s):

Thomas Bläsius ◽

Tobias Friedrich ◽

Maximilian Katzmann ◽

Anton Krohmer ◽

Jonathan Striebel

Keyword(s):

Network Models ◽

Systematic Evaluation

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What's in a model? Network models as tools instead of representations of what psychiatric disorders really are

Behavioral and Brain Sciences ◽

10.1017/s0140525x18001206 ◽

2019 ◽

Vol 42 ◽

Cited By ~ 2

Author(s):

Hanna M. van Loo ◽

Jan-Willem Romeijn

Keyword(s):

Psychiatric Disorders ◽

Network Models ◽

Model Network

AbstractNetwork models block reductionism about psychiatric disorders only if models are interpreted in a realist manner – that is, taken to represent “what psychiatric disorders really are.” A flexible and more instrumentalist view of models is needed to improve our understanding of the heterogeneity and multifactorial character of psychiatric disorders.

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Special, radical, failure of reduction in psychiatry

Behavioral and Brain Sciences ◽

10.1017/s0140525x18001164 ◽

2019 ◽

Vol 42 ◽

Author(s):

Don Ross

Keyword(s):

Mental Disorder ◽

Brain Structure ◽

Causal Structure ◽

Network Models ◽

Gambling Addiction ◽

Brain Disorder ◽

Mental Processes ◽

Special Radical ◽

Intentional Relationships

AbstractUse of network models to identify causal structure typically blocks reduction across the sciences. Entanglement of mental processes with environmental and intentional relationships, as Borsboom et al. argue, makes reduction of psychology to neuroscience particularly implausible. However, in psychiatry, a mental disorder can involve no brain disorder at all, even when the former crucially depends on aspects of brain structure. Gambling addiction constitutes an example.

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Image Analysis of Intramembrane Particles in Freeze-Fractured Biomembranes Using Computer Simulation Techniques

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100114694 ◽

1975 ◽

Vol 33 ◽

pp. 214-215

Author(s):

D.J. Benefiel ◽

R.S. Weinstein

Keyword(s):

Membrane Proteins ◽

Freeze Fracture ◽

Integral Membrane Proteins ◽

Systematic Evaluation ◽

Intramembrane Particles ◽

Modeling Methods ◽

Simulation Techniques ◽

Freeze Fracture Electron Microscopy ◽

Fracture Electron ◽

Computer Simulation Techniques

Intramembrane particles (IMP or MAP) are components of most biomembranes. They are visualized by freeze-fracture electron microscopy, and they probably represent replicas of integral membrane proteins. The presence of MAP in biomembranes has been extensively investigated but their detailed ultrastructure has been largely ignored. In this study, we have attempted to lay groundwork for a systematic evaluation of MAP ultrastructure. Using mathematical modeling methods, we have simulated the electron optical appearances of idealized globular proteins as they might be expected to appear in replicas under defined conditions. By comparing these images with the apearances of MAPs in replicas, we have attempted to evaluate dimensional and shape distortions that may be introduced by the freeze-fracture technique and further to deduce the actual shapes of integral membrane proteins from their freezefracture images.

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Application of Lattice Imaging Techniques to Amorphous Films

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100113664 ◽

1975 ◽

Vol 33 ◽

pp. 8-9

Author(s):

S. R. Herd ◽

P. Chaudhari

Keyword(s):

Nearest Neighbor ◽

Random Network ◽

Imaging Techniques ◽

Network Models ◽

Accurate Method ◽

Direct Transmission ◽

Lattice Imaging ◽

Transmission Electron ◽

Lattice Planes ◽

Nearest Neighbor Distances

Electron diffraction and direct transmission have been used extensively to study the local atomic arrangement in amorphous solids and in particular Ge. Nearest neighbor distances had been calculated from E.D. profiles and the results have been interpreted in terms of the microcrystalline or the random network models. Direct transmission electron microscopy appears the most direct and accurate method to resolve this issue since the spacial resolution of the better instruments are of the order of 3Å. In particular the tilted beam interference method is used regularly to show fringes corresponding to 1.5 to 3Å lattice planes in crystals as resolution tests.

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