Molluscum contagiosum is unique among the viral induced growths of the skin. Unlike other viral tumors, the molluscum contagiosum lesion is a mass made up of myriads of free, discrete virions. It is not a proliferating growth of epidermal keratinocytes such as one observes in the common wart. There is no better way to perceive the nature of this tumor mass than by scanning electron microscopy.Skin lesions of molluscum contagiosum were excised from patients and immediately fixed in 2.5% glutaraldehyde. After fixation the specimens were rinsed in Millonig’s Phosphate buffer. The entire lesion was than cross-sectioned with a razor blade, postfixed in 1% OsO4, rinsed again in buffer, dehydrated in grading ETOH, critical point dried, positioned on an aluminum stub and gold-coated. Examination was made using a JEOL SEM (JSM-35).