Sparse Regression Models of Pain Perception

2010 ◽  
pp. 212-223 ◽  
Author(s):  
Irina Rish ◽  
Guillermo A. Cecchi ◽  
Marwan N. Baliki ◽  
A. Vania Apkarian
Keyword(s):  
Regression Models ◽  
Pain Perception ◽  
Sparse Regression

scholarly journals Sparse regression models for unraveling group and individual associations in eQTL mapping

2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Wei Cheng ◽  
Yu Shi ◽  
Xiang Zhang ◽  
Wei Wang
Keyword(s):  
Regression Models ◽  
Eqtl Mapping ◽  
Sparse Regression

scholarly journals Partial Correlation Estimation by Joint Sparse Regression Models

2009 ◽  
Vol 104 (486) ◽  
pp. 735-746 ◽  
Author(s):  
Jie Peng ◽  
Pei Wang ◽  
Nengfeng Zhou ◽  
Ji Zhu
Keyword(s):  
Regression Models ◽  
Partial Correlation ◽  
Sparse Regression ◽  
Correlation Estimation

Visual Analysis of Brain Networks Using Sparse Regression Models

2018 ◽  
Vol 12 (1) ◽  
pp. 1-30 ◽  
Author(s):  
Lei Shi ◽  
Hanghang Tong ◽  
Madelaine Daianu ◽  
Feng Tian ◽  
Paul M. Thompson
Keyword(s):  
Regression Models ◽  
Visual Analysis ◽  
Brain Networks ◽  
Sparse Regression

scholarly journals Rugby Health and Well-Being Study: protocol for a UK-wide survey with health data cross-validation

BMJ Open ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. e041037
Author(s):  
Nirmala Kanthi Panagodage Perera ◽  
Maja R Radojčić ◽  
Stephanie R Filbay ◽  
Steffan A Griffin ◽  
Lucy Gates ◽  
...  
Keyword(s):  
Mental Health ◽  
Media Coverage ◽  
Joint Pain ◽  
Regression Models ◽  
Pain Perception ◽  
Cross Validation ◽  
Well Being ◽  
Register Data ◽  
Second Phase ◽  
Health And Well Being

IntroductionRugby football (Union and League) provides physical activity (PA) with related physical and mental health benefits. However, as a collision sport, rugby research and media coverage predominantly focus on injuries in elite players while the overall impact on health and well-being remains unclear. This study aims to provide a greater understanding of the risks and benefits of rugby participation in a diverse sample of men and women, current and former rugby Union and League players from recreational to the elite level of play. We will explore: (1) joint-specific injuries and concussion; (2) joint pain and osteoarthritis (OA); (3) medical and mental health conditions; (4) PA and sedentary behaviour and (5) well-being (quality of life, flourishing and resilience).Methods and analysisThe Rugby Health and Well-being Study is designed in two phases: (1) a UK-wide cross-sectional survey and (2) cross-validation using health register data from Scotland. Participants will be at least 16 years old, current or former rugby players who have played rugby for at least one season. We will report standardised, level of play-, sex- and age-stratified prevalence of joint injury, concussion, medical conditions and PA. We will describe injury/concussion prevention expectations and protective equipment use. Rugby-related factors associated with injury, pain, OA, PA, health and well-being will be explored in regression models. We will compare joint pain intensity and duration, elements of pain perception and well-being between recreational and elite players and further investigate these associations in regression models while controlling for confounding variables. In the second phase, we will validate self-reported with health register data, and provide further information on healthcare use.Ethics and disseminationThe Yorkshire and the Humber—Leeds East Research Ethics Committee (REC reference: 19/HY/0377) has approved this study (IRAS project ID 269424). The results will be disseminated through scientific publications, conferences and social media.

Chronic Pain: Fundamental Scientific Considerations, Specifically for Legal Claims

2013 ◽  
Vol 18 (1) ◽  
pp. 1-18 ◽  
Author(s):  
Robert J. Barth
Keyword(s):  
Health Outcomes ◽  
Pain Perception ◽  
Driving Forces ◽  
Psychological Treatment ◽  
Dominant Role ◽  
Meta Analysis ◽  
General Medicine ◽  
Pain Syndrome ◽  
Problematic Relationship

Abstract Scientific findings have indicated that psychological and social factors are the driving forces behind most chronic benign pain presentations, especially in a claim context, and are relevant to at least three of the AMA Guides publications: AMA Guides to Evaluation of Disease and Injury Causation, AMA Guides to Work Ability and Return to Work, and AMA Guides to the Evaluation of Permanent Impairment. The author reviews and summarizes studies that have identified the dominant role of financial, psychological, and other non–general medicine factors in patients who report low back pain. For example, one meta-analysis found that compensation results in an increase in pain perception and a reduction in the ability to benefit from medical and psychological treatment. Other studies have found a correlation between the level of compensation and health outcomes (greater compensation is associated with worse outcomes), and legal systems that discourage compensation for pain produce better health outcomes. One study found that, among persons with carpal tunnel syndrome, claimants had worse outcomes than nonclaimants despite receiving more treatment; another examined the problematic relationship between complex regional pain syndrome (CRPS) and compensation and found that cases of CRPS are dominated by legal claims, a disparity that highlights the dominant role of compensation. Workers’ compensation claimants are almost never evaluated for personality disorders or mental illness. The article concludes with recommendations that evaluators can consider in individual cases.

Reduction in Pain Sensitivity from Pharmacological Elevation of Blood Pressure in Persons with Chronically Low Blood Pressure

2009 ◽  
Vol 23 (3) ◽  
pp. 104-112 ◽  
Author(s):  
Stefan Duschek ◽  
Heike Heiss ◽  
Boriana Buechner ◽  
Rainer Schandry
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Pain Sensitivity ◽  
Pain Threshold ◽  
Pain Perception ◽  
Drug Effects ◽  
Pressure Effects ◽  
Double Blind ◽  
Low Blood Pressure ◽  
Present Trial

Recent studies have revealed evidence for increased pain sensitivity in individuals with chronically low blood pressure. The present trial explored whether pain sensitivity can be reduced by pharmacological elevation of blood pressure. Effects of the sympathomimetic midodrine on threshold and tolerance to heat pain were examined in 52 hypotensive persons (mean blood pressure 96/61 mmHg) based on a randomized, placebo-controlled, double-blind design. Heat stimuli were applied to the forearm via a contact thermode. Confounding of drug effects on pain perception with changes in skin temperature, temperature sensitivity, and mood were statistically controlled for. Compared to placebo, higher pain threshold and tolerance, increased blood pressure, as well as reduced heart rate were observed under the sympathomimetic condition. Increases in systolic blood pressure between points of measurement correlated positively with increases in pain threshold and tolerance, and decreases in heart rate were associated with increases in pain threshold. The findings underline the causal role of hypotension in the augmented pain sensitivity related to this condition. Pain reduction as a function of heart rate decrease suggests involvement of a baroreceptor-related mechanism in the pain attrition. The increased proneness of persons with chronic hypotension toward clinical pain is discussed.

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