Effect of Spinal Cord Injury on Nonlinear Complexity of Skin Blood Flow Oscillations

2011 ◽  
pp. 345-355 ◽  
Author(s):  
Yih-Kuen Jan ◽  
Fuyuan Liao ◽  
Stephanie Burns
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Blood Flow ◽  
Skin Blood Flow ◽  
Blood Flow Oscillations ◽  
Nonlinear Complexity ◽  
Cord Injury ◽  
Flow Oscillations ◽  
Skin Blood Flow Oscillations

The contribution of lumbar sympathetic neurones activity to rat’s skin blood flow oscillations

2000 ◽  
Vol 439 (7) ◽  
pp. R158-R160
Author(s):  
F. Bajrovic ◽  
M. Čenčur ◽  
M. Hožič ◽  
S. Ribarič ◽  
A. Stefanovska
Keyword(s):  
Blood Flow ◽  
Skin Blood Flow ◽  
Blood Flow Oscillations ◽  
Flow Oscillations ◽  
Sympathetic Neurones ◽  
Skin Blood Flow Oscillations

Effect of functional electrostimulation on impaired skin vasodilator responses to local heating in spinal cord injury

2009 ◽  
Vol 106 (4) ◽  
pp. 1065-1071 ◽  
Author(s):  
Noortje T. L. Van Duijnhoven ◽  
Thomas W. J. Janssen ◽  
Daniel J. Green ◽  
Christopher T. Minson ◽  
Maria T. E. Hopman ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Blood Flow ◽  
Skin Blood Flow ◽  
Local Heating ◽  
Axon Reflex ◽  
Doppler Flowmetry ◽  
Cord Injury ◽  
Cutaneous Vascular Conductance ◽  
Functional Electrostimulation

Spinal cord injury (SCI) induces vascular adaptations below the level of the lesion, such as impaired cutaneous vasodilation. However, the mechanisms underlying these differences are unclear. The aim of this study is to examine arm and leg cutaneous vascular conductance (CVC) responses to local heating in 17 able-bodied controls (39 ± 13 yr) and 18 SCI subjects (42 ± 8 yr). SCI subjects were counterbalanced for functional electrostimulation (FES) cycling exercise (SCI-EX, n = 9) or control (SCI-C, n = 9) and reanalyzed after 8 wk. Arm and leg skin blood flow were measured by laser-Doppler flowmetry during local heating (42°C), resulting in an axon-reflex mediated first peak, nadir, and a primarily nitric oxide-dependent plateau phase. Data were expressed as a percentage of maximal CVC (44°C). CVC responses to local heating in the paralyzed leg, but also in the forearm of SCI subjects, were lower than in able-bodied controls ( P < 0.05 and 0.01, respectively). The 8-wk intervention did not change forearm and leg CVC responses to local heating in SCI-C and SCI-EX, but increased femoral artery diameter in SCI-EX ( P < 0.05). Interestingly, findings in skin microvessels contrast with conduit arteries, where physical (in)activity contributes to adaptations in SCI. The lower CVC responses in the paralyzed legs might suggest a role for inactivity in SCI, but the presence of impaired CVC responses in the normally active forearm suggests other mechanisms. This is supported by a lack of adaptation in skin microcirculation after FES cycle training. This might relate to the less frequent and smaller magnitude of skin blood flow responses to heat stimuli, compared with controls, than physical inactivity per se.

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