Mucociliary Clearance and Mucus Secretion in the Lung

1985 ◽  
pp. 319-367 ◽  
Author(s):  
Jennifer M. Sturgess
Keyword(s):  
Mucociliary Clearance ◽  
Mucus Secretion

scholarly journals Cyclosporin A reduces airway mucus secretion and mucociliary clearance in rats

Clinics ◽  
2007 ◽  
Vol 62 (3) ◽  
pp. 345-352 ◽  
Author(s):  
Rogerio Pazetti ◽  
Paulo Manuel Pego-Fernandes ◽  
Otavio Tavares Ranzani ◽  
Edwin Roger Parra ◽  
Geraldo Lorenzi-Filho ◽  
...  
Keyword(s):  
Cyclosporin A ◽  
Mucociliary Clearance ◽  
Mucus Secretion ◽  
Airway Mucus

Effects of Various Drugs on Canine Tracheal Mucociliary Transport

1978 ◽  
Vol 87 (4) ◽  
pp. 484-490 ◽  
Author(s):  
Anthony Giordano ◽  
Douglas Holsclaw ◽  
Mitchell Litt
Keyword(s):  
Clearance Rate ◽  
Mucociliary Clearance ◽  
Mucus Secretion ◽  
Mucociliary Transport ◽  
Clearance Rates ◽  
Rheologic Properties

A study of the effects of dehydration, atropine, terbutaline and N-acetylcysteine on canine tracheobronchial mucus is presented. Mucociliary clearance rates, mucus secretion volumes and mucus rheologic properties were studied. Clearance rates were studied by a radioisotope technique, mucus collected by a canine “tracheal pouch” method and rheologic studies performed on a microrheometer. Clearance rate was unaffected by dehydration and terbutaline, increased by N-acetylcysteine and decreased by atropine. Secretion volume was increased by terbutaline while dehydration and atropine were without effect. Rheologic factors were increased by dehydration and atropine while terbutaline was without an effect. The effects of N-acetylcysteine on secretion volume and rheologic properties could not be studied because of the nature of the techniques employed.

scholarly journals Novel Roles for Chloride Channels, Exchangers, and Regulators in Chronic Inflammatory Airway Diseases

2015 ◽  
Vol 2015 ◽  
pp. 1-13 ◽  
Author(s):  
Monica Sala-Rabanal ◽  
Zeynep Yurtsever ◽  
Kayla N. Berry ◽  
Tom J. Brett
Keyword(s):  
Chloride Channel ◽  
Chloride Channels ◽  
Mucociliary Clearance ◽  
Chloride Transport ◽  
Transport Proteins ◽  
Innate Immune ◽  
Mucus Secretion ◽  
Airway Constriction ◽  
Airway Diseases

Chloride transport proteins play critical roles in inflammatory airway diseases, contributing to the detrimental aspects of mucus overproduction, mucus secretion, and airway constriction. However, they also play crucial roles in contributing to the innate immune properties of mucus and mucociliary clearance. In this review, we focus on the emerging novel roles for a chloride channel regulator (CLCA1), a calcium-activated chloride channel (TMEM16A), and two chloride exchangers (SLC26A4/pendrin and SLC26A9) in chronic inflammatory airway diseases.

Peptides derived from casein induce mucus secretion in rat jejunum: Involvement of opioid stimulation

2001 ◽  
Vol 120 (5) ◽  
pp. A675-A675
Author(s):  
F TOUMI ◽  
J CLAUSTRE ◽  
A TROMPETTE ◽  
G JOURDAN ◽  
H GUIGNARD ◽  
...  
Keyword(s):  
Mucus Secretion ◽  
Rat Jejunum

A Bacterial Signal Peptide Increases Mucociliary Clearance in Explanted Mouse Trachea

Pneumologie ◽  
2016 ◽  
Vol 70 (07) ◽  
Author(s):  
W Kummer ◽  
A Perniß ◽  
B Bufe ◽  
G Krasteva-Christ
Keyword(s):  
Signal Peptide ◽  
Mucociliary Clearance

The evaluation of nasal mucociliary clearance in patients with Helicobacter pylori infection

2019 ◽  
Vol 133 (03) ◽  
pp. 220-223
Author(s):  
S Üstün Bezgin ◽  
T Çakabay ◽  
K Irak ◽  
M Koçyiğit ◽  
B Serin Keskineğe ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Mucociliary Clearance ◽  
Endoscopic Examination ◽  
Control Group ◽  
Clearance Time ◽  
Saccharine Test ◽  
Significant Difference ◽  
And Gender ◽  
H Pylori ◽  
Nasal Mucociliary Clearance

AbstractObjectiveThis study aimed to examine nasal mucociliary clearance time in patients with Helicobacter pylori infection.MethodsFifty patients who were newly diagnosed with H pylori infection using gastric biopsy in the gastroenterology out-patient clinic, and 50 age- and gender-matched healthy adults who were admitted to the otorhinolaryngology out-patient clinic, were included in this study. After an otorhinolaryngological examination (anterior rhinoscopy and nasal endoscopic examination), the nasal mucociliary clearance time of each subject was calculated using the saccharine test.ResultsThe mean mucociliary clearance time was 06:29 ± 3:31 minutes (range, 00:55–15:19 minutes) in the control group and 10:12 ± 06:09 minutes (range, 01:28–32:00 minutes) in the study group. Comparisons of the two groups revealed a statistically significant difference (p = 0.002).ConclusionNasal mucociliary clearance time was significantly increased in patients with H pylori infection. The results suggest that H pylori infection may have an unfavourable effect on nasal mucociliary clearance.

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