Regional Cerebral Blood Flow Evaluations with Iodine 123 Amphetamine (IMP) SPECT and Xenon 133 Inhalation in Cerebrovascular Disorders

1987 ◽  
pp. 102-107 ◽  
Author(s):  
Y. Tsuda ◽  
A. Hartmann ◽  
H. J. Biersack ◽  
E. Valerius ◽  
K. Reichmann
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Cerebrovascular Disorders ◽  
Regional Cerebral Blood ◽  
Iodine 123 ◽  
Xenon 133

scholarly journals Regional Cerebral Blood Flow during Rest and Skilled Hand Movements by Xenon-133 Inhalation and Emission Computerized Tomography

1981 ◽  
Vol 1 (4) ◽  
pp. 385-389 ◽  
Author(s):  
Martin Lauritzen ◽  
Leif Henriksen ◽  
Niels A. Lassen
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Single Photon ◽  
Photon Emission ◽  
Hand Movements ◽  
Regional Cerebral Blood ◽  
Symmetric Pattern ◽  
Xenon 133 ◽  
The Right

Regional cerebral blood flow (CBF) was studied in 16 normal adult volunteers during rest and in 10 the study was repeated during skilled hand movements. A fast-rotating (“dynamic”), single-photon emission computerized tomograph (ECT) with four detector heads was used. Xenon-133 was inhaled over a 1-min period at a concentration of 10 mCi/L. The arrival and washout of the radioisotope was recorded during four 1-min periods. Two slices, 2 cm thick, 7 and 12 cm above the orbitomeatal line were obtained in every study. CBF averaged 60 ml/100 g/min (SD ± 11) in the lower slice and 51 ml/100 g/min (SD ± 13) in the upper slice. A symmetric pattern comparing right to left sides was found in both slices. Finger tapping and writing with the right hand increased CBF in specific areas of the upper slice: in the contralateral hand area by 35 ± 15% ( p < 0.025), and in the supplementary motor area on both sides by 34 ± 15% ( p < 0.025).

scholarly journals Chroma-Memo-Flow Technique for Rapid Sequential Analysis of Regional Cerebral Blood Flow (rCBF) Responses

1978 ◽  
Vol 5 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Jørn Overgaard
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Sequential Analysis ◽  
Initial Slope ◽  
Functional Tests ◽  
Regional Cerebral Blood ◽  
Flow Calculation ◽  
Channel Memory ◽  
Xenon 133

SUMMARY:This is the first report of a method of sequential regional cerebral blood flow (rCBF) analysis, called Croma-Memo-Flow. This technique is a computerized modification of the initial slope method of regional cerebral blood flow (rCBF init.), allowing temporal resolution of the flow pattern by calculation of the slopes of sequential segments of the initial 1-2 minutes of the Xenon-133 washout curve. The same theoretical analysis applies to this method as to the rCBF init. method. Each flow calculation is based on the slope of a discrete 16 second segment of the initial washout; and each second the segment is advanced by one second. A new flow calculation is made each second and is displayed as a color coded map on a TV screen. Each map is labelled, indicating the time in seconds following Xenon injection, and sequential rCBF changes during the clearance period can be immediately visualized. This allows for almost instantaneous analysis and display of rapid or transient rCBF responses to activation and deactivation of the cerebral cortices.The data is stored in a 35 channel memory for deliberate replay, photography, and analysis.Functional tests may be applied during the initial washout period and both the magnitude and chronological relationships of the evoked regional cerebrovascular responses observed. A clinical study is presented to illustrate the possibilities of applying the technique to assess cortical reactivity.

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