Maintenance Therapy of Busulfan-Induced Chronic Granulocytic Leukemia Remissions with Interferon-α2b

1988 ◽  
pp. 129-138
Author(s):  
D. E. Bergsagel
Keyword(s):  
Maintenance Therapy ◽  
Chronic Granulocytic Leukemia ◽  
Granulocytic Leukemia ◽  
Interferon Α2b

Successful Treatment of Juvenile Chronic Granulocytic Leukemia With Marrow Transplantation

PEDIATRICS ◽  
1979 ◽  
Vol 63 (1) ◽  
pp. 44-46
Author(s):  
Jean E. Sanders ◽  
C. Dean Buckner ◽  
Patricia Stewart ◽  
E. Donnall Thomas
Keyword(s):  
Bone Marrow ◽  
Maintenance Therapy ◽  
Total Body Irradiation ◽  
Marrow Transplantation ◽  
Marrow Transplant ◽  
Successful Outcome ◽  
Chronic Granulocytic Leukemia ◽  
Total Body ◽  
Granulocytic Leukemia ◽  
Disease Free

A 46-month-old boy with juvenile chronic granulocytic leukemia was treated intensively with hydroxyurea dimethyl myleran, cyclophosphamide, and total body irradiation. He then received a marrow transplant from an HL-A matched brother. Thirty-two months after the transplantation, he is hematologically normal and remains disease free on no-maintenance therapy. The successful outcome of this case suggests that a bone marrow transplant for any patient with a suitable histocompatible donor should be considered in the treatment of this disease.

Therapy of chronic granulocytic leukemia

1977 ◽  
Vol 137 (12) ◽  
pp. 1717-1718
Author(s):  
W. H. Crosby
Keyword(s):  
Chronic Granulocytic Leukemia ◽  
Granulocytic Leukemia

scholarly journals Peripheral erythroid precursor and prognosis in chronic granulocytic leukemia

Cancer ◽  
1986 ◽  
Vol 58 (2) ◽  
pp. 229-233 ◽  
Author(s):  
Alessandro Levis ◽  
Filippo Marmont ◽  
Maria A. Ciocca Vasino ◽  
Augusto Jayme ◽  
Vittorio Infelise ◽  
...  
Keyword(s):  
Chronic Granulocytic Leukemia ◽  
Erythroid Precursor ◽  
Granulocytic Leukemia

Changes in Oncogene Expression Implicated in Evolution of Chronic Granulocytic Leukemia from its Chronic Phase to Acceleration

1998 ◽  
Vol 30 (3-4) ◽  
pp. 293-306 ◽  
Author(s):  
ZoltÁN Beck ◽  
Attila Bácsi ◽  
Eszter Kovács ◽  
JolÁN Kiss ◽  
Attila Kiss ◽  
...  
Keyword(s):  
Chronic Phase ◽  
Chronic Granulocytic Leukemia ◽  
Oncogene Expression ◽  
Granulocytic Leukemia

T-cell depleted (TCD) bone marrow transplantation (BMT) for acute leukemia (AL) and chronic granulocytic leukemia (CGL)

1986 ◽  
Vol 10 (1) ◽  
pp. 123
Author(s):  
J.Y. Cahn ◽  
P. Hervé ◽  
M. Flesch ◽  
E. Plouvier ◽  
E. Racadot ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
T Cell ◽  
Acute Leukemia ◽  
Marrow Transplantation ◽  
Chronic Granulocytic Leukemia ◽  
Granulocytic Leukemia

Effect of Granulocyte Colony-Stimulating Factor Combined with Erythropoietin on Chronic Granulocytic Leukemia with Anemia and Its Effect on Nutritional Status

2021 ◽  
Vol 7 (5) ◽  
pp. 3150-3154
Author(s):  
GeLe Tong ◽  
Liusha Xu ◽  
Yanqi Leng ◽  
Pang Wu
Keyword(s):  
Nutritional Status ◽  
Immune Function ◽  
Control Group ◽  
Observation Group ◽  
Granulocyte Colony Stimulating Factor ◽  
Colony Stimulating Factor ◽  
Chronic Granulocytic Leukemia ◽  
Cd8 Cells ◽  
Stimulating Factor ◽  
Granulocytic Leukemia

Objective: To investigate the clinical effect of granulocyte colony-stimulating factor combined with erythropoietin on chronic granulocytic leukemia with anemia and its effect on nutritional status. Methods: 60 patients of chronic granulocytic leukemia of our hospital with anemia induced by maintenance chemotherapy were randomly divided into two groups. Patients in the control group received routine treatment, while patients in the observation group received basal treatment with granulocyte colony-stimulating factor and erythropoietin. The nutritional status before and after treatment as well as the immune function and the incidence of blood transfusion and adverse events were compared between the two groups. Results: There was no significant difference in hemoglobin, hematocrit, nutritional status and immune function between the two groups before treatment (P>0.05). Those after treatment were significantly higher than that before treatment (P<0.05). After treatment, the percentage of CD4* cells in the control group was significantly higher than that before treatment (P<0.05), but the percentage of CD8* cells and CD47/CD8* cells did not change significantly (P>0.05). After treatment, the concentrations of IgA, IgM and IgG in the observation group were significantly higher than those before treatment (P<0.05), but only the concentrations of IgA and IgM in the control group were significantly higher than those in the observation group after treatment (P<0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group. Conclusion: Granulocyte colony-stimulating factor combined with erythropoietin can effectively correct anemia, improve nutritional status and improve immune function in patients with chronic myelogenous leukemia.

CHRONIC GRANULOCYTIC LEUKEMIA IN CHILDHOOD

1960 ◽  
Vol 240 (5) ◽  
pp. 89-94 ◽  
Author(s):  
OʼNeill Barrett ◽  
Marcel Conrad ◽  
William H. Crosby
Keyword(s):  
Chronic Granulocytic Leukemia ◽  
Granulocytic Leukemia
Sign in / Sign up

Export Citation Format

Share Document