Immunological Aspects of Anterior Pituitary Hormones with Special Emphasis on Growth Hormone

1965 ◽  
pp. 9-21
Author(s):  
Z. Laron
Keyword(s):  
Growth Hormone ◽  
Anterior Pituitary ◽  
Pituitary Hormones ◽  
Anterior Pituitary Hormones

THE INTERACTION OF GROWTH HORMONE RELEASING HORMONE WITH OTHER HYPOTHALAMIC HORMONES ON THE RELEASE OF ANTERIOR PITUITARY HORMONES

1986 ◽  
Vol 24 (2) ◽  
pp. 149-156 ◽  
Author(s):  
B. J. LOOIJ ◽  
A. C. NIEUWENHUIJZEN KRUSEMAN ◽  
A. H. MUDDE ◽  
M. FRÖLICH ◽  
G. P. PIADITIS ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Anterior Pituitary ◽  
Pituitary Hormones ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Anterior Pituitary Hormones ◽  
Hypothalamic Hormones

Associated Hypersecretion of Anterior Pituitary Hormones other than Growth Hormone in Acromegaly

Acromegaly ◽  
1987 ◽  
pp. 179-191
Author(s):  
G. Faglia ◽  
M. Arosio ◽  
M. Bassetti ◽  
P. Beck-Peccoz ◽  
L. Guglielmino ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Anterior Pituitary ◽  
Pituitary Hormones ◽  
Anterior Pituitary Hormones

INFLUENCE OF HORMONES ON LOBULO-ALVEOLAR DIFFERENTIATION OF MOUSE MAMMARY GLANDS IN VITRO

1966 ◽  
Vol 35 (4) ◽  
pp. 331-NP ◽  
Author(s):  
RUBY R. ICHINOSE ◽  
S. NANDI
Keyword(s):  
Growth Hormone ◽  
Steroid Hormones ◽  
Anterior Pituitary ◽  
Steroid Hormone ◽  
Mammary Glands ◽  
Defined Medium ◽  
Pituitary Hormones ◽  
Anterior Pituitary Hormones

SUMMARY (1) To induce mammary differentiation in vitro, BALB/cCrgl mice were given hormones before incubation of their mammary glands in defined medium containing steroid hormones (oestradiol, progesterone and aldosterone), anterior pituitary hormones (prolactin and growth hormone), and insulin. The sequence of lobule development in vitro obtained in this way was determined by cultivation of tissues for 1, 2, 3, 4 and 5 days. Lobules appeared on the 3rd day of culture, although proliferation occurred throughout the 5-day period. (2) In two other sets of experiments, mammary glands were exposed to various combinations of hormones in culture. Survival of cultured tissues required the presence of insulin, whereas differentiation required the presence of steroid hormones, anterior pituitary hormones, and insulin. Of the steroid hormones used, aldosterone alone fulfilled the minimum steroid hormone requirement for lobule formation in vitro.

scholarly journals Evaluation of anterior pituitary hormonal profile in patients with first seizure of tonic-clonic and temporal lobe epilepsies in Al-Zahra hospital of Isfahan, Iran, during 2014-2016: comparison of hormonal profiles in 2 types of epilepsy

2019 ◽  
Vol 21 (2) ◽  
pp. 70-74
Author(s):  
Maryam Ghasemi Aliabadi ◽  
Mohammad Reza Najafi ◽  
Rokhsareh Meamar ◽  
Shahrzad Nematollahi ◽  
Noushin Mehrbod ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Temporal Lobe ◽  
Anterior Pituitary ◽  
Pituitary Hormones ◽  
Hormonal Changes ◽  
Cross Sectional ◽  
Anterior Pituitary Hormones ◽  
Significant Difference ◽  
Clonic Seizures ◽  
Stimulating Hormone

Background and aims: Temporal lobe and tonic-clonic seizures are the most common types of epilepsy. It is a disease that disrupts the regulation of the hypothalamic pituitary adrenal (HPA) axis. The disturbance in the regulation of this axis affects the secretion of hormones from the anterior pituitary. Due to the different origins of these 2 types of epilepsy listed above, this study aimed to examine their differences in the level of anterior pituitary hormones. Methods: This cross-sectional study was conducted in Al-Zahra hospital of Isfahan, Iran, from 2014 to 2016. A total of 36 patients with the idiopathic first seizure were selected for the examination including 20 patients with tonic-clonic seizure and 16 patients with temporal lobe seizure. The diagnosis of epilepsy was confirmed by a neurologist along with electroencephalogram (EEG) findings. The levels of anterior pituitary hormones including thyroid-stimulating hormone (TSH), adrenocorticotrophic hormone (ACTH), GH (growth hormone), follicle-stimulating hormone (FSH), luteinizing hormone (LH) and PRL (prolactin) were measured and compared using ELISA method in both groups. Results: The results indicated that all the anterior pituitary hormones except TSH and ACTH had higher means in the temporal lobe epilepsy than in the tonic-clonic epilepsy, but a significant difference (mean ± SD) was reported only in GH (4.59±2.95) (2.55±1.87) (P<0.005) and FSH (19.4±14.06) (4.34±2.37) (P<0.033) respectively in the temporal lobe and tonic-clonic seizures. Meanwhile, there was a significant relationship between seizure, regardless of its type, and the level of growth hormone and FSH. Conclusion: In the future, hormonal changes may be used as an adjunct to diagnose the type of epilepsy. More studies are required to confirm the findings.

Ultrastructural morphology of nontumorous lactotrophs in human pituitaries exposed to high prolactin levels

1987 ◽  
Vol 45 ◽  
pp. 896-897
Author(s):  
S. Jalalah ◽  
K. Kovacs ◽  
E. Horvath
Keyword(s):  
Anterior Pituitary ◽  
Secretory Activity ◽  
Pituitary Hormones ◽  
Feedback Mechanism ◽  
Endocrine Activity ◽  
Hormone Synthesis ◽  
Anterior Pituitary Hormones ◽  
Negative Feedback Mechanism ◽  
Ultrastructural Morphology ◽  
Transmission Electron

Lactotrophs, as many other endocrine cells, change their morphology in response to factors influencing their secretory activity. Secretion of prolactin (PRL) from lactotrophs, like that of other anterior pituitary hormones, is under the control of the hypothalamus. Unlike most anterior pituitary hormones, PRL has no apparent target gland which could modulate the endocrine activity of lactotrophs. It is generally agreed that PRL regulates its own release from lactotrophs via the short loop negative feedback mechanism exerted at the level of the hypothalamus or the pituitary. Accordingly, ultrastructural morphology of lactotrophs is not constant; it is changing in response to high PRL levels showing signs of suppressed hormone synthesis and secretion.By transmission electron microscopy and morphometry, we have studied the morphology of lactotrophs in nontumorous (NT) portions of 7 human pituitaries containing PRL-secreting adenoma; these lactotrophs were exposed to abnormally high PRL levels.

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