Acute Liver Failure in Intensive Care

Author(s):  
Andrea De Gasperi ◽  
Patrizia Andreoni ◽  
Stefania Colombo ◽  
Paola Cozzi ◽  
Ernestina Mazza

2008 ◽  
Vol 14 (S2) ◽  
pp. S85-S89 ◽  
Author(s):  
David J. Kramer ◽  
Juan M. Canabal ◽  
Lisa C. Arasi


2021 ◽  
pp. 54-55
Author(s):  
Sankar narayan mishra ◽  
Kaustav nayek ◽  
Tamal kayal ◽  
Debarshi Jana

Introduction: In the present study, etiology, important clinical features, management and outcome of acute liver failure in children admitted in Pediatric Intensive Care Unit (PICU) of BURDWAN MEDICALCOLLEGE, WB are studied. Aims and objectives:To study different clinical features among those children having acute liver failure. I. To study the management and outcome of those children with acute liver failure in the Pediatric Intensive Care Unit. Material and methods: Pediatric Intensive Care Unit of BURDWAN MEDICALCOLLEGE, WB. 1 Year [December 2019 to November 2020]. Patients from 3months of age to 12years of age are eligible for enrolment if they meet the following criteria. Conclusion: Present study showed that cerebral edema was signicantly associated with mortality whereas AKI and spontaneous bacterial peritonitis were not signicantly related with mortality. Mean TSB and Prothrobin Time were higher but mean serum albumin was lower in those cases that had died.



Critical Care ◽  
10.1186/cc279 ◽  
1998 ◽  
Vol 2 (Suppl 1) ◽  
pp. P150 ◽  
Author(s):  
AJ Ellis ◽  
A Rhodes ◽  
N Jackson ◽  
JG O'Grady ◽  
PM Harrison ◽  
...  


2018 ◽  
Vol 22 (2) ◽  
pp. 403-408 ◽  
Author(s):  
Priyanka Rajaram ◽  
Ram Subramanian


2019 ◽  
Author(s):  
Derek J Erstad ◽  
Motaz Qadan

Acute liver failure (ALF) is a rare but highly morbid condition that is optimally managed by a multidisciplinary team of surgeons, hepatologists, and intensivists at a tertiary care center that specializes in liver disorders. ALF is caused by four primary mechanisms, including viral infections (most commonly Hepatitis A and B); toxicity from acetaminophen overdose or other substances; postoperative hepatic failure ; and miscellaneous causes such as autoimmune hepatitis, genetic disorders, or idiopathic etiologies. Unlike chronic liver failure in which the body develops compensatory, protective mechanisms, ALF may be associated with severe multisystem organ involvement, including respiratory distress syndrome, renal failure, and cerebral edema. Fulminant hepatic failure represents a rapidly progressive form of ALF that portends worse prognosis. Prompt diagnosis and management of multisystem organ dysfunction in an intensive care setting is paramount to survival. However, a subset of patients will fail to improve with medical management alone. Early identification of these individuals for emergent transplant listing has been shown to improve outcomes. Multiple predictive models for ALF survival have been developed, which are based on weighted evaluation of clinical and laboratory parameters. These models may be used to facilitate treatment, predict prognosis, and guide transplant listing. In this chapter, we provide an in-depth review these concepts, focusing on the classification, epidemiology, diagnosis, and management of ALF. This review contains 5 tables and 69 references. Key Words: acute liver failure, acute respiratory distress syndrome, coagulopathy, cerebral edema, fulminant hepatic failure, hepatic necrosis, liver transplantation, metabolic disarray, multidisciplinary intensive care, prognostication



CHEST Journal ◽  
2013 ◽  
Vol 144 (4) ◽  
pp. 380A
Author(s):  
Radhika Zopey ◽  
Alexander Zider ◽  
Ronak Garg ◽  
Scott Hu ◽  
Tisha Wang ◽  
...  




2008 ◽  
Vol 28 (2) ◽  
pp. 188-200 ◽  
Author(s):  
William Bernal ◽  
Georg Auzinger ◽  
Elizabeth Sizer ◽  
Julia Wendon




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