A STUDY ON ETIOLOGY, CLINICAL FEATURES, MANAGEMENT AND OUTCOME OF ACUTE LIVER FAILURE IN PAEDIATRIC INTENSIVE CARE UNIT OF BURDWAN MEDICAL COLLEGE

2021 ◽  
pp. 54-55
Author(s):  
Sankar narayan mishra ◽  
Kaustav nayek ◽  
Tamal kayal ◽  
Debarshi Jana
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Pediatric Intensive Care Unit ◽  
Clinical Features ◽  
Paediatric Intensive Care Unit ◽  
Pediatric Intensive Care ◽  
Medical College ◽  
Bacterial Peritonitis

Introduction: In the present study, etiology, important clinical features, management and outcome of acute liver failure in children admitted in Pediatric Intensive Care Unit (PICU) of BURDWAN MEDICALCOLLEGE, WB are studied. Aims and objectives:To study different clinical features among those children having acute liver failure. I. To study the management and outcome of those children with acute liver failure in the Pediatric Intensive Care Unit. Material and methods: Pediatric Intensive Care Unit of BURDWAN MEDICALCOLLEGE, WB. 1 Year [December 2019 to November 2020]. Patients from 3months of age to 12years of age are eligible for enrolment if they meet the following criteria. Conclusion: Present study showed that cerebral edema was signicantly associated with mortality whereas AKI and spontaneous bacterial peritonitis were not signicantly related with mortality. Mean TSB and Prothrobin Time were higher but mean serum albumin was lower in those cases that had died.

scholarly journals Clinical features and outcomes of invasive pneumococcal disease in a pediatric intensive care unit

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Hsiang-Ju Hsiao ◽  
Chang-Teng Wu ◽  
Jing-Long Huang ◽  
Cheng-Hsun Chiu ◽  
Yhu-Chering Huang ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Pediatric Intensive Care Unit ◽  
Clinical Features ◽  
Invasive Pneumococcal Disease ◽  
Pneumococcal Disease ◽  
Pediatric Intensive Care

scholarly journals Clinical and Demographic Profiles of Children Presenting with Acetaminophen Induced Acute Liver Failure in a Tertiary Paediatric Intensive Care Unit of South India

2021 ◽  
Vol 41 (1) ◽  
pp. 23-28
Author(s):  
Puja Amatya ◽  
Sudeep Kumar Kapalavai ◽  
Ravi Kumar Krupanandan ◽  
Kalaimaran Sadasivam ◽  
Srinivas Sankaranarayanan ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Paediatric Intensive Care Unit ◽  
South India ◽  
Paediatric Population ◽  
Paediatric Intensive Care ◽  
Average Dose ◽  
Demographic Profiles

Introduction: Acetaminophen (APAP) is the most widely used over-the-counter antipyretic and analgesic medicine in children. Although hepatic failure and death is rare in paediatric population, it is one of the most important and dangerous presentation of acetaminophen induced toxicity in children. There is very sparse data regarding APAP induced paediatric acute liver failure in our settings, hence this study was done to know the clinical and demographic profiles as well as outcome of children with APAP induced acute liver failure. Methods: This was a retrospective study done in children aged 0 - 18 years admitted with the diagnosis of acetaminophen induced acute liver failure in a tertiary paediatric intensive care unit of South India from January 2014 to December 2018. The clinical, demographic profiles and outcome of these patients were reviewed and analysed. Results: A total of 26 children had acetaminophen induced acute liver failure. Out of 26 patients, 53.8% were males and 46.1% were females. Among these, 24 (92.3%) survived and two (7.7%) died. The average dose of acetaminophen ingested was 168.5 mg/ kg/d. The mean serum acetaminophen level was 52.3 mg/dl. The presence of low pH, hypotension and international normalised ratio (INR) value of > 4 showed bad outcome in children with acetaminophen induced acute liver failure. Conclusion: Paracetamol induced acute liver failure is rare but fatal presentation in children. Children with acidosis, shock and INR value of > 4 had poor prognosis. Hence, judicious use of different preparations as well as counselling to parents regarding use of appropriate doses in children should be done while prescribing this medicine.

scholarly journals Five years study of mortality and morbidity patterns of Tetanus cases in a Tertiary Care PICU (Pediatric Intensive Care Unit), Multan Pakistan.

2020 ◽  
Vol 27 (01) ◽  
pp. 23-28
Author(s):  
Asim Khurshid ◽  
Muhammad Amin ◽  
Muhammad Tariq Aziz ◽  
Imran Iqbal
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Pediatric Intensive Care Unit ◽  
Clinical Features ◽  
Tertiary Care ◽  
Pediatric Intensive Care ◽  
Fatal Disease ◽  
Mortality And Morbidity ◽  
Study Setting ◽  
Grade Iii

Objectives: Tetanus is an avoidable disease. Significant reduction in the incidence of tetanus is observed around the globe but in Pakistan, its incidence is still high. The objective of current study was to determine the demographic, clinical features, outcome and complications of tetanus patients admitted in Pediatric Intensive Care Unit (PICU). Study Design: This Descriptive-observational study. Setting: At PICU of The Children Hospital & ICH Multan Pakistan. Periods: 1st January 2013 to 31st December 2017. Material and Methods: A total of 77 tetanus cases admit through the study period in PICU. Clinical features, complications, duration of stay and outcome of 77 tetanus cases during study period were noted. Results: Amongst a total of 77 cases, 62 were male (80.6%) and 15(19.4%) female. Most (57.1%) were between 2 to 7 years. Twenty five (32.4%) were unvaccinated, 52 (67.6%) partially vaccinated. According to the grade of severity (Ablett classification), majority (40) were of grade-III. Regarding the outcome, 15 (19.5%) expired. Conclusion: Tetanus is a fatal disease with high mortality rate. Vaccination and right management of the disease are the best options to minimize the load of tetanus in our country.

scholarly journals Morbidity Pattern With Treatment Outcome and Predictors of Mortality of Children Admitted to Pediatric Intensive Care Unit in a Peripheral Medical College in India

2021 ◽  
Author(s):  
Pranab Kumar Dey ◽  
Arindam Ghosh ◽  
Sunil Kumar Hemram ◽  
Meghna Mukherjee ◽  
Saba Annigeri ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Pediatric Intensive Care Unit ◽  
Congenital Heart ◽  
Significant Risk ◽  
Pediatric Intensive Care ◽  
Predictors Of Mortality ◽  
Medical College ◽  
Increased Risk ◽  
One Year

To capture lapses in management, active surveillance of pediatric intensive care unit (PICU) admissions should consider as an essential tool to bring a better outcome with available resources, while there is a scarcity of data from comparatively newly set up peripheral PICU in developing countries. An observational record-based cross-sectional study was conducted in a peripheral medical college PICU over one year to evaluate morbidity pattern, outcome, and predictors of mortality. Binomial logistic regression (SPSS version-25) was used for analysis. The confidence interval (CI) of Odd’s ratio was used to report the strength of association between dependent and independent variables. Pneumonia was the major cause of admission (27%), followed by septicemia (25.5%), congenital heart diseases (12.2%), bronchiolitis (6.6%), seizure disorders (8.6%), encephalitis (5%), and meningitis (4%). 51.7% were discharged, 14.6 %were referred, 3.2% were left against medical advice, and 30.4% were expired. Pneumonia (46.44%) was the most common cause of death, followed by sepsis (42.07%), congenital heart disease (15.3%), and bronchiolitis (6.01%). The mean duration of stay in PICU was five days (range 1-31 days). Patients who required ventilation (40%) or Inotropes (55.6%) had increased risk of mortality by 14 and 8 times, respectively. Age below one year, presence of bronchiolitis, pneumonia, ARDS, encephalitis, anemia, sepsis, dyselectrolytemia, and requirement of inotropes or ventilation were statistically significant risk factors for mortality (P<0.05). These predictors of morality will help to identify severe cases, prioritize resources and focus on the preventable methods in the public such as a vaccine, creating awareness about diseases, and proper referral.

scholarly journals A study on clinical profile and outcome of patients in PICU (paediatric intensive care unit) at tertiary care unit

2019 ◽  
Vol 6 (2) ◽  
pp. 757
Author(s):  
Aruna Jyothi K. ◽  
Korisipati Ankireddy
Keyword(s):  
Intensive Care Unit ◽  
Central Nervous System ◽  
Intensive Care ◽  
Paediatric Intensive Care Unit ◽  
Tertiary Care ◽  
Pediatric Intensive Care ◽  
Medical Advice ◽  
Clinical Profile ◽  
Age Group ◽  
Medical College

Background: This study was carried out with the objectives to study the clinical profile and to find the outcome of children admitted to pediatric intensive care unit (PICU) of Kurnool medical college and hospital, Andhra Pradesh.Methods: A retrospective study was carried in children aged more than 28 days to 12 years admitted in PICU from 1st January 2016 to 31st December 2016 when a total of 600 patients were admitted.Results: Out of these, 400 (66.66%) cases were males and 200 (33.33%) cases were females. Maximum numbers of patients were in the age group of more than 28 days to 1 year which constituted 325 (54.16%) cases. This was followed by 1 year to less than 5 years age group which constituted 150 (i.e. 25%) cases. Under 5 years aged children constituted 500 (83.33%) cases. Next most common age group admitted was 5 years to 10 years with 85 (i.e. 14.16%) cases and 10 to 12 years age group constituted 40 (6.66%) cases. In this study, central nervous system was the commonest system involved (n=195, 32.5%). Other systems involved were: respiratory system (n=122, 20.33%), cardiovascular system (n=65, 10.83%), gastro-intestinal system (n=32, 5.33%), hematological (n=35, 5.83%) and renal system (n=23, 3.83%).   Other causes include infections (n=97, 16.16%), metabolic (n=17, 2.83%), down syndrome (n=7, 1.16%) and poisoning (n=7, 1.16%) etc.Conclusions: Out of the 600 patients admitted to PICU, 168 (28%) patients died. 315 (52.5%) cases improved.  117 (19.5%) cases constituted those who were shifted to higher centre or another department or were taken against medical advice.

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