Regulation of methionine-enkephalin on expression of interleukin-2 receptor α chain gene

Peptides ◽  
1995 ◽  
pp. 225-226
Author(s):  
Gang Li ◽  
Li-Chang Chen
Keyword(s):  
Interleukin 2 ◽  
Chain Gene ◽  
Methionine Enkephalin ◽  
Interleukin 2 Receptor ◽  
Α Chain

Interleukin 2 receptor α chain gene polymorphisms and risks of multiple sclerosis and neuromyelitis optica in southern Japanese

2014 ◽  
Vol 337 (1-2) ◽  
pp. 147-150 ◽  
Author(s):  
Gulibahaer Ainiding ◽  
Yuji Kawano ◽  
Shinya Sato ◽  
Noriko Isobe ◽  
Takuya Matsushita ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Neuromyelitis Optica ◽  
Gene Polymorphisms ◽  
Interleukin 2 ◽  
Chain Gene ◽  
Interleukin 2 Receptor ◽  
Α Chain

Mutation of Asp20of human interleukin-2 reveals a dual role of the p55 α chain of the interleukin-2 receptor

1993 ◽  
Vol 23 (4) ◽  
pp. 917-921 ◽  
Author(s):  
Claudia L. Flemming ◽  
Stephen J. Russell ◽  
Mary K. L. Collins
Keyword(s):  
Interleukin 2 ◽  
Dual Role ◽  
Interleukin 2 Receptor ◽  
Α Chain

Peptide nucleic acids directed to the promoter of the α-chain of the interleukin-2 receptor

1996 ◽  
Vol 1309 (3) ◽  
pp. 226-238 ◽  
Author(s):  
Danièle Praseuth ◽  
Mikhaïl Grigoriev ◽  
Anne-Laure Guieysse ◽  
Linda Louise Pritchard ◽  
Annick Harel-Bellan ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Interleukin 2 ◽  
Interleukin 2 Receptor ◽  
Α Chain

Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's

Science ◽  
1989 ◽  
Vol 244 (4904) ◽  
pp. 551-556 ◽  
Author(s):  
M Hatakeyama ◽  
M Tsudo ◽  
S Minamoto ◽  
T Kono ◽  
T Doi ◽  
...  
Keyword(s):  
Interleukin 2 ◽  
Chain Gene ◽  
Beta Chain ◽  
Interleukin 2 Receptor ◽  
Receptor Beta

scholarly journals Characterization of the human interleukin-2 receptor beta-chain gene promoter: regulation of promoter activity by ets gene products.

1993 ◽  
Vol 13 (10) ◽  
pp. 6201-6210 ◽  
Author(s):  
J X Lin ◽  
N K Bhat ◽  
S John ◽  
W S Queale ◽  
W J Leonard
Keyword(s):  
Binding Site ◽  
Phorbol Myristate Acetate ◽  
Promoter Activity ◽  
Interleukin 2 ◽  
Chain Gene ◽  
Beta Chain ◽  
Myristate Acetate ◽  
Interleukin 2 Receptor ◽  
Mg63 Cells ◽  
Beta Gene

The interleukin-2 receptor (IL-2R) beta chain (IL-2R beta) is an essential signaling component of high- and intermediate-affinity IL-2Rs. Our laboratory previously reported that a DNA fragment containing 857 bp of 5'-flanking sequence of the human IL-2R beta gene exhibited promoter activity. We have now further characterized the promoter and delineated cis-acting regulatory regions. The region downstream of -363 is critical for basal and phorbol myristate acetate-inducible IL-2R beta promoter activity and contains at least three enhancer-like regions. Among them, the -56 to -34 enhancer was the most potent and had high-level activity in two T-cell lines but not in nonlymphoid HeLaS3 and MG63 cells. This enhancer contains a GGAA Ets binding site which bound two Ets family proteins, Ets-1 and GA-binding protein in vitro. Mutation of the Ets motif strongly diminished both promoter and enhancer activities. We conclude that this Ets binding site plays a key role in regulating basal and phorbol myristate acetate-inducible IL-2R beta promoter activity and may also contribute to tissue-specific expression of the IL-2R beta gene.

Expression of Soluble Human Interleukin-2 Receptor α-Chain inEscherichia coli

1995 ◽  
Vol 6 (6) ◽  
pp. 737-747 ◽  
Author(s):  
Stella Dracheva ◽  
Robert E. Palermo ◽  
Gordon D. Powers ◽  
David S. Waugh
Keyword(s):  
Interleukin 2 ◽  
Inescherichia Coli ◽  
Interleukin 2 Receptor ◽  
Α Chain

Transcriptional regulation of the mouse interleukin-2 receptor β chain gene by Ets and Egr-1

2005 ◽  
Vol 329 (3) ◽  
pp. 1094-1101 ◽  
Author(s):  
Sang-Kyu Ye ◽  
Tack Joong Kim ◽  
Sung Sik Won ◽  
Taek Joon Yoon ◽  
Tae Kyu Park ◽  
...  
Keyword(s):  
Transcriptional Regulation ◽  
Interleukin 2 ◽  
Chain Gene ◽  
Interleukin 2 Receptor ◽  
Β Chain
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